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Powers RK, Elbasiouny SM, Rymer WZ, Heckman CJ (2012) Contribution of intrinsic properties and synaptic inputs to motoneuron discharge patterns: a simulation study. J Neurophysiol 107:808-23 [PubMed]

   Simulations of motor unit discharge patterns (Powers et al. 2011)

References and models cited by this paper

References and models that cite this paper

Alaburda A, Russo R, MacAulay N, Hounsgaard J (2005) Periodic high-conductance states in spinal neurons during scratch-like network activity in adult turtles. J Neurosci 25:6316-21 [Journal] [PubMed]
Ballou EW, Smith WB, Anelli R, Heckman CJ (2006) Measuring dendritic distribution of membrane proteins. J Neurosci Methods 156:257-66 [Journal] [PubMed]
Bean BP (2007) The action potential in mammalian central neurons. Nat Rev Neurosci 8:451-65 [Journal] [PubMed]
Bennett DJ, Hultborn H, Fedirchuk B, Gorassini M (1998) Synaptic activation of plateaus in hindlimb motoneurons of decerebrate cats. J Neurophysiol 80:2023-37 [Journal] [PubMed]
Berg RW, Alaburda A, Hounsgaard J (2007) Balanced inhibition and excitation drive spike activity in spinal half-centers. Science 315:390-3 [Journal] [PubMed]
Booth V, Rinzel J, Kiehn O (1997) Compartmental model of vertebrate motoneurons for Ca2+-dependent spiking and plateau potentials under pharmacological treatment. J Neurophysiol 78:3371-85 [Journal] [PubMed]
Bui TV, Grande G, Rose PK (2008) Relative location of inhibitory synapses and persistent inward currents determines the magnitude and mode of synaptic amplification in motoneurons. J Neurophysiol 99:583-94 [Journal] [PubMed]
Bui TV, Ter-Mikaelian M, Bedrossian D, Rose PK (2006) Computational estimation of the distribution of L-type Ca(2+) channels in motoneurons based on variable threshold of activation of persistent inward currents. J Neurophysiol 95:225-41 [Journal] [PubMed]
Carlin KP, Bui TV, Dai Y, Brownstone RM (2009) Staircase currents in motoneurons: insight into the spatial arrangement of calcium channels in the dendritic tree. J Neurosci 29:5343-53 [Journal] [PubMed]
Clements JD, Nelson PG, Redman SJ (1986) Intracellular tetraethylammonium ions enhance group Ia excitatory post-synaptic potentials evoked in cat motoneurones. J Physiol 377:267-82 [PubMed]
COOMBS JS, CURTIS DR, ECCLES JC (1957) The generation of impulses in motoneurones. J Physiol 139:232-49 [PubMed]
COOMBS JS, ECCLES JC, FATT P (1955) The electrical properties of the motoneurone membrane. J Physiol 130:291-325 [PubMed]
Crill WE (1996) Persistent sodium current in mammalian central neurons. Annu Rev Physiol 58:349-62 [Journal] [PubMed]
Cullheim S, Fleshman JW, Glenn LL, Burke RE (1987) Membrane area and dendritic structure in type-identified triceps surae alpha motoneurons. J Comp Neurol 255:68-81 [Journal] [PubMed]
De Luca CJ, LeFever RS, McCue MP, Xenakis AP (1982) Behaviour of human motor units in different muscles during linearly varying contractions. J Physiol 329:113-28 [PubMed]
Deng Z, Romer SH, Cope TC, Goss L, Nardelli P, Bullinger K, Fyffe RE (2007) Expression of small conductance Ca2-activated potassium (SK) channels in mammalian spinal motoneurons Soc Neurosci Abstr 408.417
Elbasiouny SM, Bennett DJ, Mushahwar VK (2005) Simulation of dendritic CaV1.3 channels in cat lumbar motoneurons: spatial distribution. J Neurophysiol 94:3961-74 [Journal] [PubMed]
Elbasiouny SM, Bennett DJ, Mushahwar VK (2006) Simulation of Ca2+ persistent inward currents in spinal motoneurones: mode of activation and integration of synaptic inputs. J Physiol 570:355-74 [Journal] [PubMed]
ElBasiouny SM, Schuster JE, Heckman CJ (2010) Persistent inward currents in spinal motoneurons: important for normal function but potentially harmful after spinal cord injury and in amyotrophic lateral sclerosis. Clin Neurophysiol 121:1669-79 [Journal] [PubMed]
Fleidervish IA, Friedman A, Gutnick MJ (1996) Slow inactivation of Na+ current and slow cumulative spike adaptation in mouse and guinea-pig neocortical neurones in slices. J Physiol 493 ( Pt 1):83-97 [PubMed]
Fleshman JW, Segev I, Burke RB (1988) Electrotonic architecture of type-identified alpha-motoneurons in the cat spinal cord. J Neurophysiol 60:60-85 [Journal] [PubMed]
Fuglevand AJ, Dutoit AP, Johns RK, Keen DA (2006) Evaluation of plateau-potential-mediated 'warm up' in human motor units. J Physiol 571:683-93 [Journal] [PubMed]
Gorassini M, Yang JF, Siu M, Bennett DJ (2002) Intrinsic activation of human motoneurons: possible contribution to motor unit excitation. J Neurophysiol 87:1850-8 [Journal] [PubMed]
Gorassini MA, Knash ME, Harvey PJ, Bennett DJ, Yang JF (2004) Role of motoneurons in the generation of muscle spasms after spinal cord injury. Brain 127:2247-58 [Journal] [PubMed]
Grande G, Bui TV, Rose PK (2007) Estimates of the location of L-type Ca2+ channels in motoneurons of different sizes: a computational study. J Neurophysiol 97:4023-35 [Journal] [PubMed]
Heckman CJ, Hyngstrom AS, Johnson MD (2008) Active properties of motoneurone dendrites: diffuse descending neuromodulation, focused local inhibition. J Physiol 586:1225-31 [Journal] [PubMed]
Heckman CJ, Johnson M, Mottram C, Schuster J (2008) Persistent inward currents in spinal motoneurons and their influence on human motoneuron firing patterns. Neuroscientist 14:264-75 [Journal] [PubMed]
Heckmann CJ, Gorassini MA, Bennett DJ (2005) Persistent inward currents in motoneuron dendrites: implications for motor output. Muscle Nerve 31:135-56 [Journal] [PubMed]
Hines M (1989) A program for simulation of nerve equations with branching geometries. Int J Biomed Comput 24:55-68 [PubMed]
Hornby TG, McDonagh JC, Reinking RM, Stuart DG (2002) Motoneurons: A preferred firing range across vertebrate species? Muscle Nerve 25:632-48 [Journal] [PubMed]
Hultborn H, Brownstone RB, Toth TI, Gossard JP (2004) Key mechanisms for setting the input-output gain across the motoneuron pool. Prog Brain Res 143:77-95 [PubMed]
Hyngstrom AS, Johnson MD, Miller JF, Heckman CJ (2007) Intrinsic electrical properties of spinal motoneurons vary with joint angle. Nat Neurosci 10:363-9 [Journal] [PubMed]
Ito M, Oshima T (1965) Electrical behaviour of the motoneurone membrane during intracellularly applied current steps. J Physiol 180:607-35 [PubMed]
Johnson MD, Heckman CJ (2010) Interactions between focused synaptic inputs and diffuse neuromodulation in the spinal cord. Ann N Y Acad Sci 1198:35-41 [Journal] [PubMed]
Jones SM, Lee RH (2006) Fast amplification of dynamic synaptic inputs in spinal motoneurons in vivo. J Neurophysiol 96:2200-6 [Journal] [PubMed]
Kiehn O, Eken T (1997) Prolonged firing in motor units: evidence of plateau potentials in human motoneurons? J Neurophysiol 78:3061-8 [Journal] [PubMed]
Kim H, Jones KE (2011) Asymmetric electrotonic coupling between the soma and dendrites alters the bistable firing behaviour of reduced models. J Comput Neurosci 30:659-74 [Journal] [PubMed]
Kuo CC, Bean BP (1994) Na+ channels must deactivate to recover from inactivation. Neuron 12:819-29 [PubMed]
Kuo JJ, Lee RH, Zhang L, Heckman CJ (2006) Essential role of the persistent sodium current in spike initiation during slowly rising inputs in mouse spinal neurones. J Physiol 574:819-34 [Journal] [PubMed]
Kurian M, Crook SM, Jung R (2011) Motoneuron model of self-sustained firing after spinal cord injury. J Comput Neurosci 31:625-45 [Journal] [PubMed]
   Motoneuron model of self-sustained firing after spinal cord injury (Kurian et al. 2011) [Model]
Larkman PM, Kelly JS (1992) Ionic mechanisms mediating 5-hydroxytryptamine- and noradrenaline-evoked depolarization of adult rat facial motoneurones. J Physiol 456:473-90 [PubMed]
Lee RH, Heckman CJ (1998) Bistability in spinal motoneurons in vivo: systematic variations in rhythmic firing patterns. J Neurophysiol 80:572-82 [Journal] [PubMed]
Lee RH, Heckman CJ (1998) Bistability in spinal motoneurons in vivo: systematic variations in persistent inward currents. J Neurophysiol 80:583-93 [Journal] [PubMed]
Lee RH, Heckman CJ (1999) Enhancement of bistability in spinal motoneurons in vivo by the noradrenergic alpha1 agonist methoxamine. J Neurophysiol 81:2164-74 [Journal] [PubMed]
Lee RH, Kuo JJ, Jiang MC, Heckman CJ (2003) Influence of active dendritic currents on input-output processing in spinal motoneurons in vivo. J Neurophysiol 89:27-39 [Journal] [PubMed]
Li X, Bennett DJ (2007) Apamin-sensitive calcium-activated potassium currents (SK) are activated by persistent calcium currents in rat motoneurons. J Neurophysiol 97:3314-30 [Journal] [PubMed]
Li Y, Gorassini MA, Bennett DJ (2004) Role of persistent sodium and calcium currents in motoneuron firing and spasticity in chronic spinal rats. J Neurophysiol 91:767-83 [Journal] [PubMed]
Lorincz A, Nusser Z (2008) Cell-type-dependent molecular composition of the axon initial segment. J Neurosci 28:14329-40 [Journal] [PubMed]
Manuel M, Meunier C, Donnet M, Zytnicki D (2007) Resonant or not, two amplification modes of proprioceptive inputs by persistent inward currents in spinal motoneurons. J Neurosci 27:12977-88 [Journal] [PubMed]
Migliore M, Hoffman DA, Magee JC, Johnston D (1999) Role of an A-type K+ conductance in the back-propagation of action potentials in the dendrites of hippocampal pyramidal neurons. J Comput Neurosci 7:5-15 [PubMed]
   CA1 pyramidal neuron (Migliore et al 1999) [Model]
Monster AW, Chan H (1977) Isometric force production by motor units of extensor digitorum communis muscle in man. J Neurophysiol 40:1432-43 [Journal] [PubMed]
Mottram CJ, Suresh NL, Heckman CJ, Gorassini MA, Rymer WZ (2009) Origins of abnormal excitability in biceps brachii motoneurons of spastic-paretic stroke survivors. J Neurophysiol 102:2026-38 [Journal] [PubMed]
Mottram CJ, Wallace CL, Chikando CN, Rymer WZ (2010) Origins of spontaneous firing of motor units in the spastic-paretic biceps brachii muscle of stroke survivors. J Neurophysiol 104:3168-79 [Journal] [PubMed]
Oya T, Riek S, Cresswell AG (2009) Recruitment and rate coding organisation for soleus motor units across entire range of voluntary isometric plantar flexions. J Physiol 587:4737-48 [Journal] [PubMed]
Person RS, Kudina LP (1972) Discharge frequency and discharge pattern of human motor units during voluntary contraction of muscle. Electroencephalogr Clin Neurophysiol 32:471-83 [PubMed]
Powers RK, Binder MD (2001) Input-output functions of mammalian motoneurons. Rev Physiol Biochem Pharmacol 143:137-263 [PubMed]
Royeck M, Horstmann MT, Remy S, Reitze M, Yaari Y, Beck H (2008) Role of axonal NaV1.6 sodium channels in action potential initiation of CA1 pyramidal neurons. J Neurophysiol 100:2361-80 [Journal] [PubMed]
   Axonal NaV1.6 Sodium Channels in AP Initiation of CA1 Pyramidal Neurons (Royeck et al. 2008) [Model]
Sah P (1992) Role of calcium influx and buffering in the kinetics of Ca(2+)-activated K+ current in rat vagal motoneurons. J Neurophysiol 68:2237-47 [Journal] [PubMed]
Shapiro NP, Lee RH (2007) Synaptic amplification versus bistability in motoneuron dendritic processing: a top-down modeling approach. J Neurophysiol 97:3948-60 [Journal] [PubMed]
Stephenson JL, Maluf KS (2011) Dependence of the paired motor unit analysis on motor unit discharge characteristics in the human tibialis anterior muscle. J Neurosci Methods 198:84-92 [Journal] [PubMed]
Udina E, D'Amico J, Bergquist AJ, Gorassini MA (2010) Amphetamine increases persistent inward currents in human motoneurons estimated from paired motor-unit activity. J Neurophysiol 103:1295-303 [Journal] [PubMed]
Umemiya M, Berger AJ (1994) Properties and function of low- and high-voltage-activated Ca2+ channels in hypoglossal motoneurons. J Neurosci 14:5652-60 [PubMed]
Viana F, Bayliss DA, Berger AJ (1993) Multiple potassium conductances and their role in action potential repolarization and repetitive firing behavior of neonatal rat hypoglossal motoneurons. J Neurophysiol 69:2150-63 [Journal] [PubMed]
Wienecke J, Zhang M, Hultborn H (2009) A prolongation of the postspike afterhyperpolarization following spike trains can partly explain the lower firing rates at derecruitment than those at recruitment. J Neurophysiol 102:3698-710 [Journal] [PubMed]
Zhao EY, Neuber-hess M, Fenrich KK, Maratta R, Rose PK (2010) Mapping the distribution of HCN1 channels on neck motoneurons Soc Neurosci Abstr 685.611
Allen JM, Elbasiouny SM (2018) The effects of model composition design choices on high-fidelity simulations of motoneuron recruitment and firing behaviors. J Neural Eng 15:036024 [Journal] [PubMed]
Balbi P, Martinoia S, Colombo R, Massobrio P (2014) Modelling recurrent discharge in the spinal a-motoneuron: reappraisal of the F wave. Clin Neurophysiol 125:427-9 [Journal] [PubMed]
   Recurrent discharge in a reduced model of cat spinal motoneuron (Balbi et al, 2013) [Model]
Balbi P, Martinoia S, Massobrio P (2015) Axon-somatic back-propagation in detailed models of spinal alpha motoneurons. Front Comput Neurosci 9:15 [Journal] [PubMed]
   Axon-somatic back-propagation in a detailed model of cat spinal motoneuron (Balbi et al, 2015) [Model]
Kim H (2017) Impact of the localization of dendritic calcium persistent inward current on the input-output properties of spinal motoneuron pool: a computational study. J Appl Physiol (1985) 123:1166-1187 [Journal] [PubMed]
   Locational influence of dendritic PIC on input-output properties of spinal motoneurons (Kim 2017) [Model]
Kuck A, Stegeman DF, van Asseldonk EHF (2017) Modeling trans-spinal direct current stimulation for the modulation of the lumbar spinal motor pathways J Neural Eng. 14(5):056014 [Journal] [PubMed]
Le Masson G, Przedborski S, Abbott LF (2014) A computational model of motor neuron degeneration. Neuron 83:975-88 [Journal] [PubMed]
Powers RK, Heckman CJ (2015) Contribution of intrinsic motoneuron properties to discharge hysteresis and its estimation based on paired motor unit recordings: a simulation study. J Neurophysiol 114:184-98 [Journal] [PubMed]
   Discharge hysteresis in motoneurons (Powers & Heckman 2015) [Model]
Powers RK, Heckman CJ (2017) Synaptic control of the shape of the motoneuron pool input-output function. J Neurophysiol 117:1171-1184 [Journal] [PubMed]
   Motoneuron pool input-output function (Powers & Heckman 2017) [Model]
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