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Anderson WD, Makadia HK, Greenhalgh AD, Schwaber JS, David S, Vadigepalli R (2015) Computational modeling of cytokine signaling in microglia. Mol Biosyst 11:3332-46 [PubMed]

   Microglial cytokine network (Anderson et al., 2015)

References and models cited by this paper

References and models that cite this paper

Agarwal D, Dange RB, Raizada MK, Francis J (2013) Angiotensin II causes imbalance between pro- and anti-inflammatory cytokines by modulating GSK-3ß in neuronal culture. Br J Pharmacol 169:860-74 [Journal] [PubMed]
Ajmone-Cat MA, Nicolini A, Minghetti L (2003) Prolonged exposure of microglia to lipopolysaccharide modifies the intracellular signaling pathways and selectively promotes prostaglandin E2 synthesis. J Neurochem 87:1193-203 [PubMed]
Amor S, Puentes F, Baker D, van der Valk P (2010) Inflammation in neurodegenerative diseases. Immunology 129:154-69 [Journal] [PubMed]
An GC, Faeder JR (2009) Detailed qualitative dynamic knowledge representation using a BioNetGen model of TLR-4 signaling and preconditioning. Math Biosci 217:53-63 [Journal] [PubMed]
Anastasio TJ (2015) Temporal-logic analysis of microglial phenotypic conversion with exposure to amyloid-ß. Mol Biosyst 11:434-53 [Journal] [PubMed]
Anastasio TJ (2015) Computational identification of potential multi-drug combinations for reduction of microglial inflammation in Alzheimer disease. Front Pharmacol 6:116 [Journal] [PubMed]
Azhar N, Ziraldo C, Barclay D, Rudnick DA, Squires RH, Vodovotz Y, Pediatric Acute Liver Failure Study Group (2013) Analysis of serum inflammatory mediators identifies unique dynamic networks associated with death and spontaneous survival in pediatric acute liver failure. PLoS One 8:e78202 [Journal] [PubMed]
Barone FC, Feuerstein GZ (1999) Inflammatory mediators and stroke: new opportunities for novel therapeutics. J Cereb Blood Flow Metab 19:819-34 [Journal] [PubMed]
Barzel B, Barabási AL (2013) Universality in network dynamics. Nat Phys [Journal] [PubMed]
Behar M, Hao N, Dohlman HG, Elston TC (2007) Mathematical and computational analysis of adaptation via feedback inhibition in signal transduction pathways. Biophys J 93:806-21 [Journal] [PubMed]
Bell MT, Puskas F, Agoston VA, Cleveland JC, Freeman KA, Gamboni F, Herson PS, Meng X, Smith PD, Weyant MJ, Fullerton DA, Reece TB (2013) Toll-like receptor 4-dependent microglial activation mediates spinal cord ischemia-reperfusion injury. Circulation 128:S152-6 [Journal] [PubMed]
Bezbradica JS, Rosenstein RK, DeMarco RA, Brodsky I, Medzhitov R (2014) A role for the ITAM signaling module in specifying cytokine-receptor functions. Nat Immunol 15:333-42 [Journal] [PubMed]
Bilbo SD, Biedenkapp JC, Der-Avakian A, Watkins LR, Rudy JW, Maier SF (2005) Neonatal infection-induced memory impairment after lipopolysaccharide in adulthood is prevented via caspase-1 inhibition. J Neurosci 25:8000-9 [Journal] [PubMed]
Bogdan C, Nathan C (1993) Modulation of macrophage function by transforming growth factor beta, interleukin-4, and interleukin-10. Ann N Y Acad Sci 685:713-39 [PubMed]
Bogdan C, Paik J, Vodovotz Y, Nathan C (1992) Contrasting mechanisms for suppression of macrophage cytokine release by transforming growth factor-beta and interleukin-10. J Biol Chem 267:23301-8 [PubMed]
Cai S, Zhou P, Liu Z (2013) Functional characteristics of a double negative feedback loop mediated by microRNAs. Cogn Neurodyn 7:417-29 [Journal] [PubMed]
Caldwell AB, Cheng Z, Vargas JD, Birnbaum HA, Hoffmann A (2014) Network dynamics determine the autocrine and paracrine signaling functions of TNF. Genes Dev 28:2120-33 [Journal] [PubMed]
Cambier S, Gline S, Mu D, Collins R, Araya J, Dolganov G, Einheber S, Boudreau N, Nishimura SL (2005) Integrin alpha(v)beta8-mediated activation of transforming growth factor-beta by perivascular astrocytes: an angiogenic control switch. Am J Pathol 166:1883-94 [PubMed]
Caso JR, Pradillo JM, Hurtado O, Lorenzo P, Moro MA, Lizasoain I (2007) Toll-like receptor 4 is involved in brain damage and inflammation after experimental stroke. Circulation 115:1599-608 [Journal] [PubMed]
Chao CC, Hu S, Close K, Choi CS, Molitor TW, Novick WJ, Peterson PK (1992) Cytokine release from microglia: differential inhibition by pentoxifylline and dexamethasone. J Infect Dis 166:847-53 [PubMed]
Chao CC, Hu S, Sheng WS, Peterson PK (1995) Tumor necrosis factor-alpha production by human fetal microglial cells: regulation by other cytokines. Dev Neurosci 17:97-105 [Journal] [PubMed]
Chao CC, Hu S, Sheng WS, Tsang M, Peterson PK (1995) Tumor necrosis factor-alpha mediates the release of bioactive transforming growth factor-beta in murine microglial cell cultures. Clin Immunol Immunopathol 77:358-65 [PubMed]
Chen CJ, Ou YC, Chang CY, Pan HC, Liao SL, Chen SY, Raung SL, Lai CY (2012) Glutamate released by Japanese encephalitis virus-infected microglia involves TNF-a signaling and contributes to neuronal death. Glia 60:487-501 [Journal] [PubMed]
Chen Z, Jalabi W, Hu W, Park HJ, Gale JT, Kidd GJ, Bernatowicz R, Gossman ZC, Chen JT, Dutta R, Trapp BD (2014) Microglial displacement of inhibitory synapses provides neuroprotection in the adult brain. Nat Commun 5:4486 [Journal] [PubMed]
Cheng CS, Feldman KE, Lee J, Verma S, Huang DB, Huynh K, Chang M, Ponomarenko JV, Sun SC, Benedict CA, Ghosh G, Hoffmann A (2011) The specificity of innate immune responses is enforced by repression of interferon response elements by NF-?B p50. Sci Signal 4:ra11 [Journal] [PubMed]
Cilfone NA, Perry CR, Kirschner DE, Linderman JJ (2013) Multi-scale modeling predicts a balance of tumor necrosis factor-a and interleukin-10 controls the granuloma environment during Mycobacterium tuberculosis infection. PLoS One 8:e68680 [Journal] [PubMed]
Correnti JM, Cook D, Aksamitiene E, Swarup A, Ogunnaike B, Vadigepalli R, Hoek JB (2015) Adiponectin fine-tuning of liver regeneration dynamics revealed through cellular network modelling. J Physiol 593:365-83 [Journal] [PubMed]
Dai W,Bansal L,Hahn J,Word D (2014) Parameter set selection for dynamic systems under uncertainty via dynamic optimization and hierarchical clustering AIChE Journal 60:181-192
Daun S, Rubin J, Vodovotz Y, Roy A, Parker R, Clermont G (2008) An ensemble of models of the acute inflammatory response to bacterial lipopolysaccharide in rats: results from parameter space reduction. J Theor Biol 253:843-53 [Journal] [PubMed]
David S, Kroner A (2011) Repertoire of microglial and macrophage responses after spinal cord injury. Nat Rev Neurosci 12:388-99 [Journal] [PubMed]
Dean CB, Nielsen JD (2007) Generalized linear mixed models: a review and some extensions. Lifetime Data Anal 13:497-512 [Journal] [PubMed]
Dong Y, Benveniste EN (2001) Immune function of astrocytes. Glia 36:180-90 [PubMed]
Engl HW, Flamm C, Kugler P, Lu J, Muller S, Schuster P (2009) Inverse problems in systems biology Inverse Problems 25:123014
Furchtgott LA, Chow CC, Periwal V (2009) A model of liver regeneration. Biophys J 96:3926-35 [Journal] [PubMed]
Greenhalgh AD, David S (2014) Differences in the phagocytic response of microglia and peripheral macrophages after spinal cord injury and its effects on cell death. J Neurosci 34:6316-22 [Journal] [PubMed]
Gutenkunst RN, Waterfall JJ, Casey FP, Brown KS, Myers CR, Sethna JP (2007) Universally sloppy parameter sensitivities in systems biology models. PLoS Comput Biol 3:1871-78 [Journal] [PubMed]
Hanisch UK (2002) Microglia as a source and target of cytokines. Glia 40:140-55 [Journal] [PubMed]
Heneka MT, Kummer MP, Latz E (2014) Innate immune activation in neurodegenerative disease. Nat Rev Immunol 14:463-77 [Journal] [PubMed]
Hickman SE, Kingery ND, Ohsumi TK, Borowsky ML, Wang LC, Means TK, El Khoury J (2013) The microglial sensome revealed by direct RNA sequencing. Nat Neurosci 16:1896-905 [Journal] [PubMed]
Hines ML, Morse T, Migliore M, Carnevale NT, Shepherd GM (2004) ModelDB: A Database to Support Computational Neuroscience. J Comput Neurosci 17:7-11 [Journal] [PubMed]
Hoffmann A, Levchenko A, Scott ML, Baltimore D (2002) The IkappaB-NF-kappaB signaling module: temporal control and selective gene activation. Science 298:1241-5 [Journal] [PubMed]
Hopp SC, Royer S, Brothers HM, Kaercher RM, D'Angelo H, Bardou I, Wenk GL (2014) Age-associated alterations in the time-dependent profile of pro- and anti-inflammatory proteins within the hippocampus in response to acute exposure to interleukin-1ß. J Neuroimmunol 267:86-91 [Journal] [PubMed]
Hornig M, Weissenböck H, Horscroft N, Lipkin WI (1999) An infection-based model of neurodevelopmental damage. Proc Natl Acad Sci U S A 96:12102-7 [PubMed]
Janes KA, Lauffenburger DA (2006) A biological approach to computational models of proteomic networks. Curr Opin Chem Biol 10:73-80 [Journal] [PubMed]
Joyce ME, Roberts AB, Sporn MB, Bolander ME (1990) Transforming growth factor-beta and the initiation of chondrogenesis and osteogenesis in the rat femur. J Cell Biol 110:2195-207 [PubMed]
Kettenmann H, Hanisch UK, Noda M, Verkhratsky A (2011) Physiology of microglia. Physiol Rev 91:461-553 [Journal] [PubMed]
Kholodenko BN, Kiyatkin A, Bruggeman FJ, Sontag E, Westerhoff HV, Hoek JB (2002) Untangling the wires: a strategy to trace functional interactions in signaling and gene networks. Proc Natl Acad Sci U S A 99:12841-6 [Journal] [PubMed]
Kigerl KA, Lai W, Rivest S, Hart RP, Satoskar AR, Popovich PG (2007) Toll-like receptor (TLR)-2 and TLR-4 regulate inflammation, gliosis, and myelin sparing after spinal cord injury. J Neurochem 102:37-50 [Journal] [PubMed]
Kilic U, Kilic E, Matter CM, Bassetti CL, Hermann DM (2008) TLR-4 deficiency protects against focal cerebral ischemia and axotomy-induced neurodegeneration. Neurobiol Dis 31:33-40 [Journal] [PubMed]
Kroner A, Greenhalgh AD, Zarruk JG, Passos Dos Santos R, Gaestel M, David S (2014) TNF and increased intracellular iron alter macrophage polarization to a detrimental M1 phenotype in the injured spinal cord. Neuron 83:1098-116 [Journal] [PubMed]
Le Y, Iribarren P, Gong W, Cui Y, Zhang X, Wang JM (2004) TGF-beta1 disrupts endotoxin signaling in microglial cells through Smad3 and MAPK pathways. J Immunol 173:962-8 [PubMed]
Livak KJ, Schmittgen TD (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25:402-8 [Journal] [PubMed]
Lodge PA, Sriram S (1996) Regulation of microglial activation by TGF-beta, IL-10, and CSF-1. J Leukoc Biol 60:502-8 [PubMed]
Longbrake EE, Lai W, Ankeny DP, Popovich PG (2007) Characterization and modeling of monocyte-derived macrophages after spinal cord injury. J Neurochem 102:1083-94 [Journal] [PubMed]
Ma W, Trusina A, El-Samad H, Lim WA, Tang C (2009) Defining network topologies that can achieve biochemical adaptation. Cell 138:760-73 [Journal] [PubMed]
Machta BB, Chachra R, Transtrum MK, Sethna JP (2013) Parameter space compression underlies emergent theories and predictive models. Science 342:604-7 [Journal] [PubMed]
Maiti S,Dai W,Alaniz R,Hahn J,Jayaraman A (2015) S. Maiti, W. Dai, R. Alaniz, J. Hahn, and A. Jayaraman. Mathematical Modeling of Pro- and Anti-Inflammatory Signaling in Macrophages Processes 3(1):1-18
Marino S, Cilfone NA, Mattila JT, Linderman JJ, Flynn JL, Kirschner DE (2015) Macrophage polarization drives granuloma outcome during Mycobacterium tuberculosis infection. Infect Immun 83:324-38 [Journal] [PubMed]
McCoy MK, Tansey MG (2008) TNF signaling inhibition in the CNS: implications for normal brain function and neurodegenerative disease. J Neuroinflammation 5:45 [Journal] [PubMed]
Meyer-Hermann M, Figge MT, Straub RH (2009) Mathematical modeling of the circadian rhythm of key neuroendocrine-immune system players in rheumatoid arthritis: a systems biology approach. Arthritis Rheum 60:2585-94 [Journal] [PubMed]
Miller GM, Ogunnaike BA, Schwaber JS, Vadigepalli R (2010) Robust dynamic balance of AP-1 transcription factors in a neuronal gene regulatory network. BMC Syst Biol 4:171 [Journal] [PubMed]
   Activator protein 1(AP-1) transcriptional regulatory model in brainstem neurons (Makadia et al 2015) [Model]
Minogue AM, Barrett JP, Lynch MA (2012) LPS-induced release of IL-6 from glia modulates production of IL-1ß in a JAK2-dependent manner. J Neuroinflammation 9:126 [Journal] [PubMed]
Mocellin S, Panelli MC, Wang E, Nagorsen D, Marincola FM (2003) The dual role of IL-10. Trends Immunol 24:36-43 [PubMed]
Morgan TE, Rozovsky I, Sarkar DK, Young-Chan CS, Nichols NR, Laping NJ, Finch CE (2000) Transforming growth factor-beta1 induces transforming growth factor-beta1 and transforming growth factor-beta receptor messenger RNAs and reduces complement C1qB messenger RNA in rat brain microglia. Neuroscience 101:313-21 [PubMed]
Morris MK, Saez-Rodriguez J, Clarke DC, Sorger PK, Lauffenburger DA (2011) Training signaling pathway maps to biochemical data with constrained fuzzy logic: quantitative analysis of liver cell responses to inflammatory stimuli. PLoS Comput Biol 7:e1001099 [Journal] [PubMed]
Moya C, Huang Z, Cheng P, Jayaraman A, Hahn J (2011) Investigation of IL-6 and IL-10 signalling via mathematical modelling. IET Syst Biol 5:15 [Journal] [PubMed]
Naiki Y, Michelsen KS, Zhang W, Chen S, Doherty TM, Arditi M (2005) Transforming growth factor-beta differentially inhibits MyD88-dependent, but not TRAM- and TRIF-dependent, lipopolysaccharide-induced TLR4 signaling. J Biol Chem 280:5491-5 [Journal] [PubMed]
Neher JJ, Brown GC (2007) Neurodegeneration in models of Gram-positive bacterial infections of the central nervous system. Biochem Soc Trans 35:1166-7 [Journal] [PubMed]
Nguyen TT, Calvano SE, Lowry SF, Androulakis IP (2013) An agent-based model of cellular dynamics and circadian variability in human endotoxemia. PLoS One 8:e55550 [Journal] [PubMed]
Nimmerjahn A, Kirchhoff F, Helmchen F (2005) Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo. Science 308:1314-8 [Journal] [PubMed]
Nørgaard P, Spang-Thomsen M, Poulsen HS (1996) Expression and autoregulation of transforming growth factor beta receptor mRNA in small-cell lung cancer cell lines. Br J Cancer 73:1037-43 [PubMed]
Olson JK, Miller SD (2004) Microglia initiate central nervous system innate and adaptive immune responses through multiple TLRs. J Immunol 173:3916-24 [PubMed]
Pan H, Ding E, Hu M, Lagoo AS, Datto MB, Lagoo-Deenadayalan SA (2010) SMAD4 is required for development of maximal endotoxin tolerance. J Immunol 184:5502-9 [Journal] [PubMed]
Parakalan R, Jiang B, Nimmi B, Janani M, Jayapal M, Lu J, Tay SS, Ling EA, Dheen ST (2012) Transcriptome analysis of amoeboid and ramified microglia isolated from the corpus callosum of rat brain. BMC Neurosci 13:64 [Journal] [PubMed]
Park KM, Bowers WJ (2010) Tumor necrosis factor-alpha mediated signaling in neuronal homeostasis and dysfunction. Cell Signal 22:977-83 [Journal] [PubMed]
Parkhurst CN, Yang G, Ninan I, Savas JN, Yates JR, Lafaille JJ, Hempstead BL, Littman DR, Gan WB (2013) Microglia promote learning-dependent synapse formation through brain-derived neurotrophic factor. Cell 155:1596-609 [Journal] [PubMed]
Perry VH, Cunningham C, Holmes C (2007) Systemic infections and inflammation affect chronic neurodegeneration. Nat Rev Immunol 7:161-7 [Journal] [PubMed]
Pickering M, Cumiskey D, O'Connor JJ (2005) Actions of TNF-alpha on glutamatergic synaptic transmission in the central nervous system. Exp Physiol 90:663-70 [Journal] [PubMed]
Pribiag H, Stellwagen D (2013) TNF-a downregulates inhibitory neurotransmission through protein phosphatase 1-dependent trafficking of GABA(A) receptors. J Neurosci 33:15879-93 [Journal] [PubMed]
Puri IK, Li L (2010) Mathematical modeling for the pathogenesis of Alzheimer's disease. PLoS One 5:e15176 [Journal] [PubMed]
Raue A, Karlsson J, Saccomani MP, Jirstrand M, Timmer J (2014) Comparison of approaches for parameter identifiability analysis of biological systems. Bioinformatics 30:1440-8 [Journal] [PubMed]
Ray JC, Wang J, Chan J, Kirschner DE (2008) The timing of TNF and IFN-gamma signaling affects macrophage activation strategies during Mycobacterium tuberculosis infection. J Theor Biol 252:24-38 [Journal] [PubMed]
Reynolds A, Rubin J, Clermont G, Day J, Vodovotz Y, Bard Ermentrout G (2006) A reduced mathematical model of the acute inflammatory response: I. Derivation of model and analysis of anti-inflammation. J Theor Biol 242:220-36 [Journal] [PubMed]
Riazi K, Galic MA, Kuzmiski JB, Ho W, Sharkey KA, Pittman QJ (2008) Microglial activation and TNFalpha production mediate altered CNS excitability following peripheral inflammation. Proc Natl Acad Sci U S A 105:17151-6 [Journal] [PubMed]
Rock RB, Gekker G, Hu S, Sheng WS, Cheeran M, Lokensgard JR, Peterson PK (2004) Role of microglia in central nervous system infections. Clin Microbiol Rev 17:942-64, table of contents [Journal] [PubMed]
Rodriguez-Fernandez M, Grosman B, Yuraszeck TM, Helwig BG, Leon LR, Doyle FJ (2013) Modeling the intra- and extracellular cytokine signaling pathway under heat stroke in the liver. PLoS One 8:e73393 [Journal] [PubMed]
Saez-Rodriguez J, Alexopoulos LG, Epperlein J, Samaga R, Lauffenburger DA, Klamt S, Sorger PK (2009) Discrete logic modelling as a means to link protein signalling networks with functional analysis of mammalian signal transduction. Mol Syst Biol 5:331 [Journal] [PubMed]
Saijo K, Glass CK (2011) Microglial cell origin and phenotypes in health and disease. Nat Rev Immunol 11:775-87 [Journal] [PubMed]
Saltelli A (2008) Global Sensitivity Analysis: The Primer
Savageau MA (1969) Biochemical systems analysis. II. The steady-state solutions for an n-pool system using a power-law approximation. J Theor Biol 25:370-9 [PubMed]
Schafer DP, Lehrman EK, Stevens B (2013) The "quad-partite" synapse: microglia-synapse interactions in the developing and mature CNS. Glia 61:24-36 [Journal] [PubMed]
Shao H, He Y, Li KC, Zhou X (2013) A system mathematical model of a cell-cell communication network in amyotrophic lateral sclerosis. Mol Biosyst 9:398-406 [Journal] [PubMed]
Sheng WS, Hu S, Kravitz FH, Peterson PK, Chao CC (1995) Tumor necrosis factor alpha upregulates human microglial cell production of interleukin-10 in vitro. Clin Diagn Lab Immunol 2:604-8 [PubMed]
Sheppard PW, Sun X, Emery JF, Giffard RG, Khammash M (2011) Quantitative characterization and analysis of the dynamic NF-?B response in microglia. BMC Bioinformatics 12:276 [Journal] [PubMed]
Sheppard PW, Sun X, Khammash M, Giffard RG (2014) Overexpression of heat shock protein 72 attenuates NF-?B activation using a combination of regulatory mechanisms in microglia. PLoS Comput Biol 10:e1003471 [Journal] [PubMed]
Stellwagen D, Malenka RC (2006) Synaptic scaling mediated by glial TNF-alpha. Nature 440:1054-9 [Journal] [PubMed]
Szretter KJ, Samuel MA, Gilfillan S, Fuchs A, Colonna M, Diamond MS (2009) The immune adaptor molecule SARM modulates tumor necrosis factor alpha production and microglia activation in the brainstem and restricts West Nile Virus pathogenesis. J Virol 83:9329-38 [Journal] [PubMed]
Tang SC, Arumugam TV, Xu X, Cheng A, Mughal MR, Jo DG, Lathia JD, Siler DA, Chigurupati S, Ouyang X, Magnus T, Camandola S, Mattson MP (2007) Pivotal role for neuronal Toll-like receptors in ischemic brain injury and functional deficits. Proc Natl Acad Sci U S A 104:13798-803 [Journal] [PubMed]
Tarantola A (2006) Popper, Bayes and the inverse problem Nature Physics 2:492-494
Tarantola S,Becker W,Zeitz D (2012) On the Performance of quasi-Monte Carlo and Latin Supercube sampling in global sensitivity analysis Computer Physics Communications 183:1061-1072
Tellinghuisen J (2008) Chapter 23. Stupid Statistics! Methods in Cell Biology, Correia IJJ:William Detrich H, ed. pp.737
Trapp BD, Wujek JR, Criste GA, Jalabi W, Yin X, Kidd GJ, Stohlman S, Ransohoff R (2007) Evidence for synaptic stripping by cortical microglia. Glia 55:360-8 [Journal] [PubMed]
Valeyev NV, Hundhausen C, Umezawa Y, Kotov NV, Williams G, Clop A, Ainali C, Ouzounis C, Tsoka S, Nestle FO (2010) A systems model for immune cell interactions unravels the mechanism of inflammation in human skin. PLoS Comput Biol 6:e1001024 [Journal] [PubMed]
Van Obberghen-Schilling E, Roche NS, Flanders KC, Sporn MB, Roberts AB (1988) Transforming growth factor beta 1 positively regulates its own expression in normal and transformed cells. J Biol Chem 263:7741-6 [PubMed]
Vereyken EJ, Heijnen PD, Baron W, de Vries EH, Dijkstra CD, Teunissen CE (2011) Classically and alternatively activated bone marrow derived macrophages differ in cytoskeletal functions and migration towards specific CNS cell types. J Neuroinflammation 8:58 [Journal] [PubMed]
Villiger PM, Kusari AB, ten Dijke P, Lotz M (1993) IL-1 beta and IL-6 selectively induce transforming growth factor-beta isoforms in human articular chondrocytes. J Immunol 151:3337-44 [PubMed]
Vincent VA, Tilders FJ, Van Dam AM (1998) Production, regulation and role of nitric oxide in glial cells. Mediators Inflamm 7:239-55 [Journal] [PubMed]
Vitkovic L, Konsman JP, Bockaert J, Dantzer R, Homburger V, Jacque C (2000) Cytokine signals propagate through the brain. Mol Psychiatry 5:604-15 [PubMed]
Vodovotz Y, Bogdan C, Paik J, Xie QW, Nathan C (1993) Mechanisms of suppression of macrophage nitric oxide release by transforming growth factor beta. J Exp Med 178:605-13 [PubMed]
Vodovotz Y, Chesler L, Chong H, Kim SJ, Simpson JT, DeGraff W, Cox GW, Roberts AB, Wink DA, Barcellos-Hoff MH (1999) Regulation of transforming growth factor beta1 by nitric oxide. Cancer Res 59:2142-9 [PubMed]
Wang W, Hu D, Xiong H (2008) Macrophage attenuation of neuronal excitability: implications for pathogenesis of neurodegenerative disorders. Glia 56:241-6 [Journal] [PubMed]
Welser-Alves JV, Milner R (2013) Microglia are the major source of TNF-a and TGF-ß1 in postnatal glial cultures; regulation by cytokines, lipopolysaccharide, and vitronectin. Neurochem Int 63:47-53 [Journal] [PubMed]
Werner SL, Barken D, Hoffmann A (2005) Stimulus specificity of gene expression programs determined by temporal control of IKK activity. Science 309:1857-61 [Journal] [PubMed]
Whitney NP, Eidem TM, Peng H, Huang Y, Zheng JC (2009) Inflammation mediates varying effects in neurogenesis: relevance to the pathogenesis of brain injury and neurodegenerative disorders. J Neurochem 108:1343-59 [Journal] [PubMed]
Williamson LL, Sholar PW, Mistry RS, Smith SH, Bilbo SD (2011) Microglia and memory: modulation by early-life infection. J Neurosci 31:15511-21 [Journal] [PubMed]
Wu KL, Chan SH, Chan JY (2012) Neuroinflammation and oxidative stress in rostral ventrolateral medulla contribute to neurogenic hypertension induced by systemic inflammation. J Neuroinflammation 9:212 [Journal] [PubMed]
Yang (2011) Convergence and uncertainty analyses in Monte-Carlo based sensitivity analysis Environ. Modell. Softw. 26:444-457
Yiu HH, Graham AL, Stengel RF (2012) Dynamics of a cytokine storm. PLoS One 7:e45027 [Journal] [PubMed]
Zhang Y, Chen K, Sloan SA, Bennett ML, Scholze AR, O'Keeffe S, Phatnani HP, Guarnieri P, Caneda C, Ruderisch N, Deng S, Liddelow SA, Zhang C, Daneman R, Maniatis T, Barres BA, Wu JQ (2014) An RNA-sequencing transcriptome and splicing database of glia, neurons, and vascular cells of the cerebral cortex. J Neurosci 34:11929-47 [Journal] [PubMed]
Ziraldo C, Mi Q, An G, Vodovotz Y (2013) Computational Modeling of Inflammation and Wound Healing. Adv Wound Care (New Rochelle) 2:527-537 [Journal] [PubMed]
Zoppoli P, Morganella S, Ceccarelli M (2010) TimeDelay-ARACNE: Reverse engineering of gene networks from time-course data by an information theoretic approach. BMC Bioinformatics 11:154 [Journal] [PubMed]
Zubcevic J, Waki H, Raizada MK, Paton JF (2011) Autonomic-immune-vascular interaction: an emerging concept for neurogenic hypertension. Hypertension 57:1026-33 [Journal] [PubMed]
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