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Venugopal S, Hamm TM, Crook SM, Jung R (2011) Modulation of inhibitory strength and kinetics facilitates regulation of persistent inward currents and motoneuron excitability following spinal cord injury. J Neurophysiol 106:2167-79 [PubMed]

   Inhibitory control of motoneuron excitability (Venugopal et al 2011)

References and models cited by this paper

References and models that cite this paper

Adams MM, Hicks AL (2005) Spasticity after spinal cord injury. Spinal Cord 43:577-86 [Journal] [PubMed]
Bareyre FM, Schwab ME (2003) Inflammation, degeneration and regeneration in the injured spinal cord: insights from DNA microarrays. Trends Neurosci 26:555-63 [Journal] [PubMed]
Bennett DJ, Hultborn H, Fedirchuk B, Gorassini M (1998) Synaptic activation of plateaus in hindlimb motoneurons of decerebrate cats. J Neurophysiol 80:2023-37 [Journal] [PubMed]
Bennett DJ, Li Y, Siu M (2001) Plateau potentials in sacrocaudal motoneurons of chronic spinal rats, recorded in vitro. J Neurophysiol 86:1955-71 [Journal] [PubMed]
Boorman GI, Lee RG, Becker WJ, Windhorst UR (1996) Impaired "natural reciprocal inhibition" in patients with spasticity due to incomplete spinal cord injury. Electroencephalogr Clin Neurophysiol 101:84-92 [Journal] [PubMed]
Booth V, Rinzel J (1995) A minimal, compartmental model for a dendritic origin of bistability of motoneuron firing patterns. J Comput Neurosci 2:299-312 [PubMed]
Booth V, Rinzel J, Kiehn O (1997) Compartmental model of vertebrate motoneurons for Ca2+-dependent spiking and plateau potentials under pharmacological treatment. J Neurophysiol 78:3371-85 [Journal] [PubMed]
Bose P, Parmer R, Reier PJ, Thompson FJ (2005) Morphological changes of the soleus motoneuron pool in chronic midthoracic contused rats. Exp Neurol 191:13-23 [Journal] [PubMed]
Boulenguez P, Liabeuf S, Bos R, Bras H, Jean-Xavier C, Brocard C, Stil A, Darbon P, Cattaert D, Delpire E, Marsala M, Vinay L (2010) Down-regulation of the potassium-chloride cotransporter KCC2 contributes to spasticity after spinal cord injury. Nat Med 16:302-7 [Journal] [PubMed]
BROOKS VB, WILSON VJ (1958) Localization of stretch reflexes by recurrent inhibition. Science 127:472-3 [Journal] [PubMed]
Bui TV, Grande G, Rose PK (2008) Multiple modes of amplification of synaptic inhibition to motoneurons by persistent inward currents. J Neurophysiol 99:571-82 [Journal] [PubMed]
Bui TV, Grande G, Rose PK (2008) Relative location of inhibitory synapses and persistent inward currents determines the magnitude and mode of synaptic amplification in motoneurons. J Neurophysiol 99:583-94 [Journal] [PubMed]
Carlin KP, Jones KE, Jiang Z, Jordan LM, Brownstone RM (2000) Dendritic L-type calcium currents in mouse spinal motoneurons: implications for bistability. Eur J Neurosci 12:1635-46 [PubMed]
   Dendritic L-type Ca currents in motoneurons (Carlin et al 2000) [Model]
Chen XY, Wolpaw JR (1994) Triceps surae motoneuron morphology in the rat: a quantitative light microscopic study. J Comp Neurol 343:143-57 [Journal] [PubMed]
Cullheim S, Kellerth JO (1981) Two kinds of recurrent inhibition of cat spinal alpha-motoneurones as differentiated pharmacologically. J Physiol 312:209-24 [PubMed]
Dourado M, Sargent PB (2002) Properties of nicotinic receptors underlying Renshaw cell excitation by alpha-motor neurons in neonatal rat spinal cord. J Neurophysiol 87:3117-25 [Journal] [PubMed]
Elbasiouny SM, Bennett DJ, Mushahwar VK (2006) Simulation of Ca2+ persistent inward currents in spinal motoneurones: mode of activation and integration of synaptic inputs. J Physiol 570:355-74 [Journal] [PubMed]
Ermentrout GB (2002) Simulating, Analyzing, and Animating Dynamical System: A Guide to XPPAUT for Researchers and Students Society for Industrial and Applied Mathematics (SIAM)
Ermentrout GB, Terman DH (2010) Mathematical Foundations of Neuroscience Interdisciplinary Applied Mathematics, Antman SS:Marsden JE:Sirovich L:Wiggins, ed. pp.1 [Journal]
   Mathematical Foundations of Neuroscience (Ermentrout and Terman 2010) [Model]
Fyffe RE (1991) Spatial distribution of recurrent inhibitory synapses on spinal motoneurons in the cat. J Neurophysiol 65:1134-49 [Journal] [PubMed]
Gazula VR, Roberts M, Luzzio C, Jawad AF, Kalb RG (2004) Effects of limb exercise after spinal cord injury on motor neuron dendrite structure. J Comp Neurol 476:130-45 [Journal] [PubMed]
Gorassini MA, Knash ME, Harvey PJ, Bennett DJ, Yang JF (2004) Role of motoneurons in the generation of muscle spasms after spinal cord injury. Brain 127:2247-58 [Journal] [PubMed]
Gracies JM, Nance P, Elovic E, McGuire J, Simpson DM (1997) Traditional pharmacological treatments for spasticity. Part II: General and regional treatments. Muscle Nerve Suppl 6:S92-120 [PubMed]
Graham J, Booth V, Jung R (2005) Modeling motoneurons after spinal cord injury: Persistent inward currents and plateau potentials Neurocomputing 65-66:719-726
Granit R, Haase J, Rutledge LT (1960) Recurrent inhibition in relation to frequency of firing and limitation of discharge rate of extensor motoneurones. J Physiol 154:308-28 [Journal] [PubMed]
Hamm TM, Sasaki S, Stuart DG, Windhorst U, Yuan CS (1987) The measurement of single motor-axon recurrent inhibitory post-synaptic potentials in the cat. J Physiol 388:631-51
Harvey PJ, Li X, Li Y, Bennett DJ (2006) 5-HT2 receptor activation facilitates a persistent sodium current and repetitive firing in spinal motoneurons of rats with and without chronic spinal cord injury. J Neurophysiol 96:1158-70 [Journal] [PubMed]
Harvey PJ, Li X, Li Y, Bennett DJ (2006) Endogenous monoamine receptor activation is essential for enabling persistent sodium currents and repetitive firing in rat spinal motoneurons. J Neurophysiol 96:1171-86 [Journal] [PubMed]
Heckman CJ (1994) Alterations in synaptic input to motoneurons during partial spinal cord injury. Med Sci Sports Exerc 26:1480-90 [PubMed]
Hounsgaard J, Hultborn H, Jespersen B, Kiehn O (1988) Bistability of alpha-motoneurones in the decerebrate cat and in the acute spinal cat after intravenous 5-hydroxytryptophan. J Physiol 405:345-67 [PubMed]
Hultborn H, Denton ME, Wienecke J, Nielsen JB (2003) Variable amplification of synaptic input to cat spinal motoneurones by dendritic persistent inward current. J Physiol 552:945-52 [Journal] [PubMed]
Jean-Xavier C, Mentis GZ, O'Donovan MJ, Cattaert D, Vinay L (2007) Dual personality of GABA/glycine-mediated depolarizations in immature spinal cord. Proc Natl Acad Sci U S A 104:11477-82 [Journal] [PubMed]
Jonas P, Bischofberger J, Sandkühler J (1998) Corelease of two fast neurotransmitters at a central synapse. Science 281:419-24 [PubMed]
Kakinohana O, Hefferan MP, Nakamura S, Kakinohana M, Galik J, Tomori Z, Marsala J, Yaksh TL, Marsala M (2006) Development of GABA-sensitive spasticity and rigidity in rats after transient spinal cord ischemia: a qualitative and quantitative electrophysiological and histopathological study. Neuroscience 141:1569-83 [Journal] [PubMed]
Katz R (1999) Presynaptic inhibition in humans: a comparison between normal and spastic patients. J Physiol Paris 93:379-85 [PubMed]
Katz R, Pierrot-Deseilligny E (1999) Recurrent inhibition in humans. Prog Neurobiol 57:325-55 [PubMed]
Khristy W,Ali NJ,Bravo AB,de Leon R,Roy RR,Zhong H,London NJ,Edgerton VR,Tillakaratne NJ (2009) Changes in GABAA receptor subunit gamma 2 in extensor and flexor motoneurons and astrocytes after spinal cord transection and motor training Brain Res 1273:9-17
Kiehn O, Kjaerulff O, Tresch MC, Harris-Warrick RM (2000) Contributions of intrinsic motor neuron properties to the production of rhythmic motor output in the mammalian spinal cord. Brain Res Bull 53:649-59 [PubMed]
Kitzman P (2005) Alteration in axial motoneuronal morphology in the spinal cord injured spastic rat. Exp Neurol 192:100-8 [Journal] [PubMed]
Kjaerulff O, Kiehn O (2001) 5-HT modulation of multiple inward rectifiers in motoneurons in intact preparations of the neonatal rat spinal cord. J Neurophysiol 85:580-93 [Journal] [PubMed]
Knopp A, Frahm C, Fidzinski P, Witte OW, Behr J (2008) Loss of GABAergic neurons in the subiculum and its functional implications in temporal lobe epilepsy. Brain 131:1516-27 [Journal] [PubMed]
Kurian M, Crook SM, Jung R (2011) Motoneuron model of self-sustained firing after spinal cord injury. J Comput Neurosci 31:625-45 [Journal] [PubMed]
   Motoneuron model of self-sustained firing after spinal cord injury (Kurian et al. 2011) [Model]
Lee RH, Heckman CJ (1998) Bistability in spinal motoneurons in vivo: systematic variations in persistent inward currents. J Neurophysiol 80:583-93 [Journal] [PubMed]
Lee RH, Heckman CJ (2000) Adjustable amplification of synaptic input in the dendrites of spinal motoneurons in vivo. J Neurosci 20:6734-40 [PubMed]
Li X, Bennett DJ (2007) Apamin-sensitive calcium-activated potassium currents (SK) are activated by persistent calcium currents in rat motoneurons. J Neurophysiol 97:3314-30 [Journal] [PubMed]
Li X, Murray K, Harvey PJ, Ballou EW, Bennett DJ (2007) Serotonin facilitates a persistent calcium current in motoneurons of rats with and without chronic spinal cord injury. J Neurophysiol 97:1236-46 [Journal] [PubMed]
Li Y, Bennett DJ (2003) Persistent sodium and calcium currents cause plateau potentials in motoneurons of chronic spinal rats. J Neurophysiol 90:857-69 [Journal] [PubMed]
Li Y, Gorassini MA, Bennett DJ (2004) Role of persistent sodium and calcium currents in motoneuron firing and spasticity in chronic spinal rats. J Neurophysiol 91:767-83 [Journal] [PubMed]
Li Y, Harvey PJ, Li X, Bennett DJ (2004) Spastic long-lasting reflexes of the chronic spinal rat studied in vitro. J Neurophysiol 91:2236-46 [Journal] [PubMed]
Lindsay AD, Binder MD (1991) Distribution of effective synaptic currents underlying recurrent inhibition in cat triceps surae motoneurons. J Neurophysiol 65:168-77 [Journal] [PubMed]
Maltenfort MG, McCurdy ML, Phillips CA, Turkin VV, Hamm TM (2004) Location and magnitude of conductance changes produced by Renshaw recurrent inhibition in spinal motoneurons. J Neurophysiol 92:1417-32 [Journal] [PubMed]
Mazzocchio R, Rossi A (1997) Involvement of spinal recurrent inhibition in spasticity. Further insight into the regulation of Renshaw cell activity. Brain 120 ( Pt 6):991-1003 [Journal] [PubMed]
McCurdy ML, Hamm TM (1994) Topography of recurrent inhibitory postsynaptic potentials between individual motoneurons in the cat. J Neurophysiol 72:214-26 [Journal] [PubMed]
Murray KC, Nakae A, Stephens MJ, Rank M, D'Amico J, Harvey PJ, Li X, Harris RL, Ballou EW, Anelli R, Heckman CJ, Mashimo T, Vavrek R, Sanelli L, Gorassini MA, Bennett DJ, Fouad K (2010) Recovery of motoneuron and locomotor function after spinal cord injury depends on constitutive activity in 5-HT2C receptors. Nat Med 16:694-700 [Journal] [PubMed]
Nielsen JB, Crone C, Hultborn H (2007) The spinal pathophysiology of spasticity--from a basic science point of view. Acta Physiol (Oxf) 189:171-80 [Journal] [PubMed]
Norton JA, Bennett DJ, Knash ME, Murray KC, Gorassini MA (2008) Changes in sensory-evoked synaptic activation of motoneurons after spinal cord injury in man. Brain 131:1478-91 [Journal] [PubMed]
Powers RK (1993) A variable-threshold motoneuron model that incorporates time- and voltage-dependent potassium and calcium conductances. J Neurophysiol 70:246-62 [Journal] [PubMed]
Prather JF, Powers RK, Cope TC (2001) Amplification and linear summation of synaptic effects on motoneuron firing rate. J Neurophysiol 85:43-53 [Journal] [PubMed]
Robinson GA, Goldberger ME (1986) The development and recovery of motor function in spinal cats. II. Pharmacological enhancement of recovery. Exp Brain Res 62:387-400 [Journal] [PubMed]
Ross HG, Cleveland S, Haase J (1976) Quantitative relation between discharge frequencies of a Renshaw cell and an intracellularly depolarized motoneuron. Neurosci Lett 3:129-32 [PubMed]
Russier M, Kopysova IL, Ankri N, Ferrand N, Debanne D (2002) GABA and glycine co-release optimizes functional inhibition in rat brainstem motoneurons in vitro. J Physiol 541:123-37 [PubMed]
Rybak IA, Shevtsova NA, Ptak K, McCrimmon DR (2004) Intrinsic bursting activity in the pre-Bötzinger complex: role of persistent sodium and potassium currents. Biol Cybern 90:59-74 [Journal] [PubMed]
Sadlaoud K, Tazerart S, Brocard C, Jean-Xavier C, Portalier P, Brocard F, Vinay L, Bras H (2010) Differential plasticity of the GABAergic and glycinergic synaptic transmission to rat lumbar motoneurons after spinal cord injury. J Neurosci 30:3358-69 [Journal] [PubMed]
Schneider SP, Fyffe RE (1992) Involvement of GABA and glycine in recurrent inhibition of spinal motoneurons. J Neurophysiol 68:397-406 [Journal] [PubMed]
Schwindt P, Crill W (1984) In Membrane properties of cat spinal motoneurons Handbook Of The Spinal Cord, Dairdoff RH, ed.
Shapiro S (1997) Neurotransmission by neurons that use serotonin, noradrenaline, glutamate, glycine, and gamma-aminobutyric acid in the normal and injured spinal cord. Neurosurgery 40:168-76; discussion 177 [Journal] [PubMed]
Shefner JM, Berman SA, Sarkarati M, Young RR (1992) Recurrent inhibition is increased in patients with spinal cord injury. Neurology 42:2162-8 [Journal] [PubMed]
Turkin VV, O'Neill D, Jung R, Iarkov A, Hamm TM (2010) Characteristics and organization of discharge properties in rat hindlimb motoneurons. J Neurophysiol 104:1549-65 [Journal] [PubMed]
Van Keulen L (1981) Autogenetic recurrent inhibition of individual spinal motoneurones of the cat. Neurosci Lett 21:297-300 [PubMed]
Venugopal S, Travers JB, Terman DH (2007) A computational model for motor pattern switching between taste-induced ingestion and rejection oromotor behaviors. J Comput Neurosci 22:223-38 [Journal] [PubMed]
Venugopal S,Crook SM,Hamm TM,Jung R (2009) A computational study of the interaction between persistent inward currents and recurrent inhibition of alpha motoneurons before and after spinal cord injury (Abstract) Soc Neurosci Abstr 657.10
Venugopal S,Crook SM,Hamm TM,Jung R (2009) A computational study of the interaction between persistent inward currents and recurrent inhibition of alpha motoneurons before and after spinal cord injury (Abstract) Soc Neurosci Abstr 657.10
Venugopal S,Crook SM,Kurian M,Jung R (2009) Role of inhibition in the suppression of alpha motoneuron hyper-excitability following chronic incomplete spinal cord injury BMC Neurosci 10 10(suppl 1):158
Venugopal S,Crook SM,Kurian M,Jung R (2009) Role of inhibition in the suppression of alpha motoneuron hyper-excitability following chronic incomplete spinal cord injury BMC Neurosci 10 10(suppl 1):158
Venugopal S,Hamm TM,Jung R (2010) Role of low and high-voltage activated Ca2 dependent K currents in the control of alpha-motoneuron discharge and its implication in hyperreflexia BMC Neurosci 11 11(Suppl 1):158
Young RR (1994) Spasticity: a review Neurology 44:S12-S20
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