Citation Relationships

Legends: Link to a Model Reference cited by multiple papers


Dougalis AG, Matthews GAC, Liss B, Ungless MA (2017) Ionic currents influencing spontaneous firing and pacemaker frequency in dopamine neurons of the ventrolateral periaqueductal gray and dorsal raphe nucleus (vlPAG/DRN): A voltage-clamp and computational modelling study. J Comput Neurosci 42:275-305 [PubMed]

  • Dopamine neuron of the vent. periaqu. gray and dors. raphe nucleus (vlPAG/DRN) (Dougalis et al 2017)

References and models cited by this paper

References and models that cite this paper

Beier KT, Steinberg EE, DeLoach KE, Xie S, Miyamichi K, Schwarz L, Gao XJ, Kremer EJ, Malenka RC, Luo L (2015) Circuit Architecture of VTA Dopamine Neurons Revealed by Systematic Input-Output Mapping. Cell 162:622-34 [Journal] [PubMed]
Bishop MW, Chakraborty S, Matthews GA, Dougalis A, Wood NW, Festenstein R, Ungless MA (2010) Hyperexcitable substantia nigra dopamine neurons in PINK1- and HtrA2/Omi-deficient mice. J Neurophysiol 104:3009-20 [Journal] [PubMed]
Branch SY, Sharma R, Beckstead MJ (2014) Aging decreases L-type calcium channel currents and pacemaker firing fidelity in substantia nigra dopamine neurons. J Neurosci 34:9310-8 [Journal] [PubMed]
Brevi S, de Curtis M, Magistretti J (2001) Pharmacological and biophysical characterization of voltage-gated calcium currents in the endopiriform nucleus of the guinea pig. J Neurophysiol 85:2076-87 [Journal] [PubMed]
Brown DA, Adams PR (1980) Muscarinic suppression of a novel voltage-sensitive K+ current in a vertebrate neurone. Nature 283:673-6 [PubMed]
Brown DA, Passmore GM (2009) Neural KCNQ (Kv7) channels. Br J Pharmacol 156:1185-95 [Journal] [PubMed]
Budde T, Meuth S, Pape HC (2002) Calcium-dependent inactivation of neuronal calcium channels. Nat Rev Neurosci 3:873-83 [Journal] [PubMed]
Catterall WA (2000) Structure and regulation of voltage-gated Ca2+ channels. Annu Rev Cell Dev Biol 16:521-55 [Journal] [PubMed]
Deignan J, Luján R, Bond C, Riegel A, Watanabe M, Williams JT, Maylie J, Adelman JP (2012) SK2 and SK3 expression differentially affect firing frequency and precision in dopamine neurons. Neuroscience 217:67-76 [Journal] [PubMed]
Ding S, Wei W, Zhou FM (2011) Molecular and functional differences in voltage-activated sodium currents between GABA projection neurons and dopamine neurons in the substantia nigra. J Neurophysiol 106:3019-34 [Journal] [PubMed]
Dougalis AG, Matthews GAC, Bishop MW, Brischoux F, Kobayashi K, Ungless MA (2012) Functional properties of dopamine neurons and co-expression of vasoactive intestinal polypeptide in the dorsal raphe nucleus and ventro-lateral periaqueductal grey. Eur J Neurosci 36:3322-3332 [Journal] [PubMed]
Drion G, Bonjean M, Waroux O, Scuvée-Moreau J, Liégeois JF, Sejnowski TJ, Sepulchre R, Seutin V (2010) M-type channels selectively control bursting in rat dopaminergic neurons. Eur J Neurosci 31:827-35 [Journal] [PubMed]
Drion G, Massotte L, Sepulchre R, Seutin V (2011) How modeling can reconcile apparently discrepant experimental results: the case of pacemaking in dopaminergic neurons. PLoS Comput Biol 7:e1002050 [Journal] [PubMed]
Edwards FA, Konnerth A, Sakmann B, Takahashi T (1989) A thin slice preparation for patch clamp recordings from neurones of the mammalian central nervous system. Pflugers Arch 414:600-12 [PubMed]
Flores JA, El Banoua F, Galán-Rodríguez B, Fernandez-Espejo E (2004) Opiate anti-nociception is attenuated following lesion of large dopamine neurons of the periaqueductal grey: critical role for D1 (not D2) dopamine receptors. Pain 110:205-14 [Journal] [PubMed]
Flores JA, Galan-Rodriguez B, Ramiro-Fuentes S, Fernandez-Espejo E (2006) Role for dopamine neurons of the rostral linear nucleus and periaqueductal gray in the rewarding and sensitizing properties of heroin. Neuropsychopharmacology 31:1475-88 [Journal] [PubMed]
Giannattasio B, Jones SW, Scarpa A (1991) Calcium currents in the A7r5 smooth muscle-derived cell line. Calcium-dependent and voltage-dependent inactivation. J Gen Physiol 98:987-1003 [PubMed]
Grace AA, Bunney BS (1983) Intracellular and extracellular electrophysiology of nigral dopaminergic neurons--2. Action potential generating mechanisms and morphological correlates. Neuroscience 10:317-31 [PubMed]
Grace AA, Bunney BS (1983) Intracellular and extracellular electrophysiology of nigral dopaminergic neurons--1. Identification and characterization. Neuroscience 10:301-15 [PubMed]
Grace AA, Bunney BS (1984) The control of firing pattern in nigral dopamine neurons: single spike firing. J Neurosci 4:2866-76 [PubMed]
Grace AA, Bunney BS (1984) The control of firing pattern in nigral dopamine neurons: burst firing. J Neurosci 4:2877-90 [PubMed]
Grace AA, Bunney BS, Moore H, Todd CL (1997) Dopamine-cell depolarization block as a model for the therapeutic actions of antipsychotic drugs. Trends Neurosci 20:31-7 [Journal] [PubMed]
Grace AA, Onn SP (1989) Morphology and electrophysiological properties of immunocytochemically identified rat dopamine neurons recorded in vitro. J Neurosci 9:3463-81 [PubMed]
Guzman JN, Sánchez-Padilla J, Chan CS, Surmeier DJ (2009) Robust pacemaking in substantia nigra dopaminergic neurons. J Neurosci 29:11011-9 [Journal] [PubMed]
Guzman JN, Sanchez-Padilla J, Wokosin D, Kondapalli J, Ilijic E, Schumacker PT, Surmeier DJ (2010) Oxidant stress evoked by pacemaking in dopaminergic neurons is attenuated by DJ-1. Nature 468:696-700 [Journal] [PubMed]
Haack JA, Rosenberg RL (1994) Calcium-dependent inactivation of L-type calcium channels in planar lipid bilayers. Biophys J 66:1051-60 [Journal] [PubMed]
Hadley JK, Noda M, Selyanko AA, Wood IC, Abogadie FC, Brown DA (2000) Differential tetraethylammonium sensitivity of KCNQ1-4 potassium channels. Br J Pharmacol 129:413-5 [Journal] [PubMed]
Hansen HH, Ebbesen C, Mathiesen C, Weikop P, Rønn LC, Waroux O, Scuvée-Moreau J, Seutin V, Mikkelsen JD (2006) The KCNQ channel opener retigabine inhibits the activity of mesencephalic dopaminergic systems of the rat. J Pharmacol Exp Ther 318:1006-19 [Journal] [PubMed]
Hille B (2001) Ionic Channels of Excitable Membranes
Hines ML, Carnevale NT (1997) The NEURON simulation environment. Neural Comput 9:1179-209 [PubMed]
Hokfelt T,Martensson R,Bjorklund A,Kleinau S,Goldstein M (1984) Distribution of tyrosine-hydroxylaseimmunoreactive neurons in the rat brain Handbook of chemical neuroanatomy, Bjorklund A:Hokfelt T, ed. pp.277
Itri JN, Michel S, Vansteensel MJ, Meijer JH, Colwell CS (2005) Fast delayed rectifier potassium current is required for circadian neural activity. Nat Neurosci 8:650-6 [Journal] [PubMed]
Jackson AC, Yao GL, Bean BP (2004) Mechanism of spontaneous firing in dorsomedial suprachiasmatic nucleus neurons. J Neurosci 24:7985-98 [Journal] [PubMed]
Kang Y, Kitai ST (1993) A whole cell patch-clamp study on the pacemaker potential in dopaminergic neurons of rat substantia nigra compacta. Neurosci Res 18:209-21 [PubMed]
Kang Y, Kitai ST (1993) Calcium spike underlying rhythmic firing in dopaminergic neurons of the rat substantia nigra. Neurosci Res 18:195-207 [PubMed]
Keja JA, Stoof JC, Kits KS (1992) Dopamine D2 receptor stimulation differentially affects voltage-activated calcium channels in rat pituitary melanotropic cells. J Physiol 450:409-35 [PubMed]
Khaliq ZM, Bean BP (2008) Dynamic, nonlinear feedback regulation of slow pacemaking by A-type potassium current in ventral tegmental area neurons. J Neurosci 28:10905-17 [Journal] [PubMed]
Khaliq ZM, Bean BP (2010) Pacemaking in dopaminergic ventral tegmental area neurons: depolarizing drive from background and voltage-dependent sodium conductances. J Neurosci 30:7401-13 [Journal] [PubMed]
Kimm T, Bean BP (2014) Inhibition of A-type potassium current by the peptide toxin SNX-482. J Neurosci 34:9182-9 [Journal] [PubMed]
Kimm T, Khaliq ZM, Bean BP (2015) Differential Regulation of Action Potential Shape and Burst-Frequency Firing by BK and Kv2 Channels in Substantia Nigra Dopaminergic Neurons. J Neurosci 35:16404-17 [Journal] [PubMed]
Koyama S, Appel SB (2006) Characterization of M-current in ventral tegmental area dopamine neurons. J Neurophysiol 96:535-43 [Journal] [PubMed]
Koyama S, Appel SB (2006) A-type K+ current of dopamine and GABA neurons in the ventral tegmental area. J Neurophysiol 96:544-54 [Journal] [PubMed]
Koyama S, Brodie MS, Appel SB (2007) Ethanol inhibition of m-current and ethanol-induced direct excitation of ventral tegmental area dopamine neurons. J Neurophysiol 97:1977-85 [Journal] [PubMed]
Koyama S, Kanemitsu Y, Weight FF (2005) Spontaneous activity and properties of two types of principal neurons from the ventral tegmental area of rat. J Neurophysiol 93:3282-93 [Journal] [PubMed]
Lacey MG, Mercuri NB, North RA (1989) Two cell types in rat substantia nigra zona compacta distinguished by membrane properties and the actions of dopamine and opioids. J Neurosci 9:1233-41 [PubMed]
Lammel S, Hetzel A, Häckel O, Jones I, Liss B, Roeper J (2008) Unique properties of mesoprefrontal neurons within a dual mesocorticolimbic dopamine system. Neuron 57:760-73 [Journal] [PubMed]
Lammel S, Ion DI, Roeper J, Malenka RC (2011) Projection-specific modulation of dopamine neuron synapses by aversive and rewarding stimuli. Neuron 70:855-62 [Journal] [PubMed]
Lerner TN, Shilyansky C, Davidson TJ, Evans KE, Beier KT, Zalocusky KA, Crow AK, Malenka RC, Luo L, Tomer R, Deisseroth K (2015) Intact-Brain Analyses Reveal Distinct Information Carried by SNc Dopamine Subcircuits. Cell 162:635-47 [Journal] [PubMed]
Li C, McCall NM, Lopez AJ, Kash TL (2013) Alcohol effects on synaptic transmission in periaqueductal gray dopamine neurons. Alcohol 47:279-87 [Journal] [PubMed]
Li C, Sugam JA, Lowery-Gionta EG, McElligott ZA, McCall NM, Lopez AJ, McKlveen JM, Pleil KE, Kash TL (2016) Mu Opioid Receptor Modulation of Dopamine Neurons in the Periaqueductal Gray/Dorsal Raphe: A Role in Regulation of Pain. Neuropsychopharmacology 41:2122-32 [Journal] [PubMed]
Liss B, Franz O, Sewing S, Bruns R, Neuhoff H, Roeper J (2001) Tuning pacemaker frequency of individual dopaminergic neurons by Kv4.3L and KChip3.1 transcription. EMBO J 20:5715-24 [Journal] [PubMed]
Lu J, Jhou TC, Saper CB (2006) Identification of wake-active dopaminergic neurons in the ventral periaqueductal gray matter. J Neurosci 26:193-202 [Journal] [PubMed]
Magistretti J, Castelli L, Forti L, D'Angelo E (2006) Kinetic and functional analysis of transient, persistent and resurgent sodium currents in rat cerebellar granule cells in situ: an electrophysiological and modelling study. J Physiol 573:83-106 [Journal] [PubMed]
Malin SA, Nerbonne JM (2002) Delayed rectifier K+ currents, IK, are encoded by Kv2 alpha-subunits and regulate tonic firing in mammalian sympathetic neurons. J Neurosci 22:10094-105 [PubMed]
Margolis EB, Lock H, Hjelmstad GO, Fields HL (2006) The ventral tegmental area revisited: is there an electrophysiological marker for dopaminergic neurons? J Physiol 577:907-24 [Journal] [PubMed]
Mercuri NB, Bonci A, Calabresi P, Stratta F, Stefani A, Bernardi G (1994) Effects of dihydropyridine calcium antagonists on rat midbrain dopaminergic neurones. Br J Pharmacol 113:831-8 [PubMed]
Milescu LS, Bean BP, Smith JC (2010) Isolation of somatic Na+ currents by selective inactivation of axonal channels with a voltage prepulse. J Neurosci 30:7740-8 [Journal] [PubMed]
Mosharov EV, Larsen KE, Kanter E, Phillips KA, Wilson K, Schmitz Y, Krantz DE, Kobayashi K, Edwards RH, Sulzer D (2009) Interplay between cytosolic dopamine, calcium, and alpha-synuclein causes selective death of substantia nigra neurons. Neuron 62:218-29 [Journal] [PubMed]
Nedergaard S, Flatman JA, Engberg I (1993) Nifedipine- and omega-conotoxin-sensitive Ca2+ conductances in guinea-pig substantia nigra pars compacta neurones. J Physiol 466:727-47 [PubMed]
Neuhoff H, Neu A, Liss B, Roeper J (2002) I(h) channels contribute to the different functional properties of identified dopaminergic subpopulations in the midbrain. J Neurosci 22:1290-302 [PubMed]
Philippart F, Destreel G, Merino-Sepúlveda P, Henny P, Engel D, Seutin V (2016) Differential Somatic Ca2+ Channel Profile in Midbrain Dopaminergic Neurons. J Neurosci 36:7234-45 [Journal] [PubMed]
Pignatelli A, Kobayashi K, Okano H, Belluzzi O (2005) Functional properties of dopaminergic neurones in the mouse olfactory bulb. J Physiol 564:501-14 [Journal] [PubMed]
Poetschke C, Dragicevic E, Duda J, Benkert J, Dougalis A, DeZio R, Snutch TP, Striessnig J, Liss B (2015) Compensatory T-type Ca2+ channel activity alters D2-autoreceptor responses of Substantia nigra dopamine neurons from Cav1.3 L-type Ca2+ channel KO mice. Sci Rep 5:13688 [Journal] [PubMed]
Pollack AE (2001) Anatomy, physiology, and pharmacology of the basal ganglia. Neurol Clin 19:523-34, v [PubMed]
Poulin JF, Zou J, Drouin-Ouellet J, Kim KY, Cicchetti F, Awatramani RB (2014) Defining midbrain dopaminergic neuron diversity by single-cell gene expression profiling. Cell Rep 9:930-43 [Journal] [PubMed]
Puopolo M, Raviola E, Bean BP (2007) Roles of subthreshold calcium current and sodium current in spontaneous firing of mouse midbrain dopamine neurons. J Neurosci 27:645-56 [Journal] [PubMed]
Putzier I, Kullmann PH, Horn JP, Levitan ES (2009) Cav1.3 channel voltage dependence, not Ca2+ selectivity, drives pacemaker activity and amplifies bursts in nigral dopamine neurons. J Neurosci 29:15414-9 [Journal] [PubMed]
Schultz W (1998) Predictive reward signal of dopamine neurons. J Neurophysiol 80:1-27 [Journal] [PubMed]
Seutin V, Massotte L, Renette MF, Dresse A (2001) Evidence for a modulatory role of Ih on the firing of a subgroup of midbrain dopamine neurons. Neuroreport 12:255-8 [PubMed]
Shah MM, Migliore M, Brown DA (2011) Differential effects of Kv7 (M-) channels on synaptic integration in distinct subcellular compartments of rat hippocampal pyramidal neurons. J Physiol 589:6029-38 [Journal] [PubMed]
  • CA1 pyramidal neurons: effects of Kv7 (M-) channels on synaptic integration (Shah et al. 2011) [Model]
Silva NL, Pechura CM, Barker JL (1990) Postnatal rat nigrostriatal dopaminergic neurons exhibit five types of potassium conductances. J Neurophysiol 64:262-72 [Journal] [PubMed]
Stuart GJ, Dodt HU, Sakmann B (1993) Patch-clamp recordings from the soma and dendrites of neurons in brain slices using infrared video microscopy. Pflugers Arch 423:511-8 [PubMed]
Subramaniam M, Althof D, Gispert S, Schwenk J, Auburger G, Kulik A, Fakler B, Roeper J (2014) Mutant a-synuclein enhances firing frequencies in dopamine substantia nigra neurons by oxidative impairment of A-type potassium channels. J Neurosci 34:13586-99 [Journal] [PubMed]
Surmeier DJ, Guzman JN, Sanchez-Padilla J, Schumacker PT (2011) The role of calcium and mitochondrial oxidant stress in the loss of substantia nigra pars compacta dopaminergic neurons in Parkinson's disease. Neuroscience 198:221-31 [Journal] [PubMed]
Surmeier DJ, Schumacker PT (2013) Calcium, bioenergetics, and neuronal vulnerability in Parkinson's disease. J Biol Chem 288:10736-41 [Journal] [PubMed]
Tucker KR, Huertas MA, Horn JP, Canavier CC, Levitan ES (2012) Pacemaker rate and depolarization block in nigral dopamine neurons: a somatic sodium channel balancing act. J Neurosci 32:14519-31 [Journal] [PubMed]
Wilson CJ, Callaway JC (2000) Coupled oscillator model of the dopaminergic neuron of the substantia nigra. J Neurophysiol 83:3084-100 [Journal] [PubMed]
Wladyka CL, Kunze DL (2006) KCNQ/M-currents contribute to the resting membrane potential in rat visceral sensory neurons. J Physiol 575:175-89 [Journal] [PubMed]
Wolfart J, Neuhoff H, Franz O, Roeper J (2001) Differential expression of the small-conductance, calcium-activated potassium channel SK3 is critical for pacemaker control in dopaminergic midbrain neurons. J Neurosci 21:3443-56 [PubMed]
Wolfart J, Roeper J (2002) Selective coupling of T-type calcium channels to SK potassium channels prevents intrinsic bursting in dopaminergic midbrain neurons. J Neurosci 22:3404-13 [Journal] [PubMed]
Xiao J, Cai Y, Yen J, Steffen M, Baxter DA, Feigenspan A, Marshak D (2004) Voltage-clamp analysis and computational model of dopaminergic neurons from mouse retina. Vis Neurosci 21:835-49 [Journal] [PubMed]
Zhao S, Maxwell S, Jimenez-Beristain A, Vives J, Kuehner E, Zhao J, O'Brien C, de Felipe C, Semina E, Li M (2004) Generation of embryonic stem cells and transgenic mice expressing green fluorescence protein in midbrain dopaminergic neurons. Eur J Neurosci 19:1133-40 [Journal] [PubMed]
(85 refs)