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Helfer P, Shultz TR (2018) Coupled feedback loops maintain synaptic long-term potentiation: A computational model arXiv

   PKMZ synthesis and AMPAR regulation in late long-term synaptic potentiation (Helfer & Shultz 2018)

References and models cited by this paper

References and models that cite this paper

Abraham WC (2003) How long will long-term potentiation last? Philos Trans R Soc Lond B Biol Sci 358:735-44 [Journal] [PubMed]
Ahmadian G, Ju W, Liu L, Wyszynski M, Lee SH, Dunah AW, Taghibiglou C, Wang Y, Lu J, Wong TP, Sheng M, Wang YT (2004) Tyrosine phosphorylation of GluR2 is required for insulin-stimulated AMPA receptor endocytosis and LTD. EMBO J 23:1040-50 [Journal] [PubMed]
Baldi E, Bucherelli C (2015) Brain sites involved in fear memory reconsolidation and extinction of rodents. Neurosci Biobehav Rev 53:160-90 [Journal] [PubMed]
Ben Mamou C, Gamache K, Nader K (2006) NMDA receptors are critical for unleashing consolidated auditory fear memories. Nat Neurosci 9:1237-9 [Journal] [PubMed]
Besnard A, Caboche J, Laroche S (2012) Reconsolidation of memory: a decade of debate. Prog Neurobiol 99:61-80 [Journal] [PubMed]
Bliss TV, Collingridge GL (1993) A synaptic model of memory: long-term potentiation in the hippocampus. Nature 361:31-9 [Journal] [PubMed]
Bliss TV, Lomo T (1973) Long-lasting potentiation of synaptic transmission in the dentate area of the anaesthetized rabbit following stimulation of the perforant path. J Physiol 232:331-56 [PubMed]
Bourtchouladze R, Abel T, Berman N, Gordon R, Lapidus K, Kandel ER (1998) Different training procedures recruit either one or two critical periods for contextual memory consolidation, each of which requires protein synthesis and PKA. Learn Mem 5:365-74 [PubMed]
Bramham CR, Wells DG (2007) Dendritic mRNA: transport, translation and function. Nat Rev Neurosci 8:776-89 [Journal] [PubMed]
Brebner K, Wong TP, Liu L, Liu Y, Campsall P, Gray S, Phelps L, Phillips AG, Wang YT (2005) Nucleus accumbens long-term depression and the expression of behavioral sensitization. Science 310:1340-3 [Journal] [PubMed]
Brebner K,Phillips AG,Wang YT,Wong TP (2006) Interference Peptides: A Novel Therapeutic Approach Targeting Synaptic Plasticity in Drug Addiction Molecular Mechanisms of Synaptogenesis :473-484 [Journal]
Cajal SRY (1894) The Croonian Lecture: La Fine Structure des Centres Nerveux Proc R Soc Lond. 55:444-468 [Journal]
Cao Y, Samuels DC (2009) Discrete stochastic simulation methods for chemically reacting systems. Methods Enzymol 454:115-40 [Journal] [PubMed]
Clem RL, Huganir RL (2010) Calcium-permeable AMPA receptor dynamics mediate fear memory erasure. Science 330:1108-12 [Journal] [PubMed]
Clopath C, Ziegler L, Vasilaki E, Büsing L, Gerstner W (2008) Tag-trigger-consolidation: a model of early and late long-term-potentiation and depression. PLoS Comput Biol 4:e1000248 [Journal] [PubMed]
   Tag Trigger Consolidation (Clopath and Ziegler et al. 2008) [Model]
Davis HP, Squire LR (1984) Protein synthesis and memory: a review. Psychol Bull 96:518-59 [PubMed]
Debiec J, LeDoux JE, Nader K (2002) Cellular and systems reconsolidation in the hippocampus. Neuron 36:527-38 [PubMed]
Doyle M, Kiebler MA (2011) Mechanisms of dendritic mRNA transport and its role in synaptic tagging. EMBO J 30:3540-52 [Journal] [PubMed]
Dudai Y (2004) The neurobiology of consolidations, or, how stable is the engram? Annu Rev Psychol 55:51-86 [Journal] [PubMed]
Fonseca R, Nägerl UV, Bonhoeffer T (2006) Neuronal activity determines the protein synthesis dependence of long-term potentiation. Nat Neurosci 9:478-80 [Journal] [PubMed]
Frankland PW, Bontempi B (2005) The organization of recent and remote memories. Nat Rev Neurosci 6:119-30 [Journal] [PubMed]
Frey U, Huang YY, Kandel ER (1993) Effects of cAMP simulate a late stage of LTP in hippocampal CA1 neurons. Science 260:1661-4 [PubMed]
Frey U, Krug M, Reymann KG, Matthies H (1988) Anisomycin, an inhibitor of protein synthesis, blocks late phases of LTP phenomena in the hippocampal CA1 region in vitro. Brain Res 452:57-65 [PubMed]
Frey U, Morris RG (1997) Synaptic tagging and long-term potentiation. Nature 385:533-6 [Journal] [PubMed]
Gillespie DT (1977) Exact stochastic simulation of coupled chemical reactions. Journal Of Physical Chemistry 81:2340-2361
Gonze D, Abou-Jaoudé W, Ouattara DA, Halloy J (2011) How molecular should your molecular model be? On the level of molecular detail required to simulate biological networks in systems and synthetic biology. Methods Enzymol 487:171-215 [Journal] [PubMed]
Hardt O, Nader K, Wang YT (2014) GluA2-dependent AMPA receptor endocytosis and the decay of early and late long-term potentiation: possible mechanisms for forgetting of short- and long-term memories. Philos Trans R Soc Lond B Biol Sci 369:20130141 [Journal] [PubMed]
Harris EW, Ganong AH, Cotman CW (1984) Long-term potentiation in the hippocampus involves activation of N-methyl-D-aspartate receptors. Brain Res 323:132-7 [PubMed]
Helfer P,Shultz TR (2018) A Computational Model of Systems Memory Reconsolidation and Extinction. Manuscript submitted for publication
Henley JM, Barker EA, Glebov OO (2011) Routes, destinations and delays: recent advances in AMPA receptor trafficking. Trends Neurosci 34:258-68 [Journal] [PubMed]
Henley JM, Wilkinson KA (2013) AMPA receptor trafficking and the mechanisms underlying synaptic plasticity and cognitive aging. Dialogues Clin Neurosci 15:11-27 [PubMed]
Hernández AI, Oxberry WC, Crary JF, Mirra SS, Sacktor TC (2014) Cellular and subcellular localization of PKM?. Philos Trans R Soc Lond B Biol Sci 369:20130140 [Journal] [PubMed]
Hong I, Kim J, Kim J, Lee S, Ko HG, Nader K, Kaang BK, Tsien RW, Choi S (2013) AMPA receptor exchange underlies transient memory destabilization on retrieval. Proc Natl Acad Sci U S A 110:8218-23 [Journal] [PubMed]
Huang YY, Li XC, Kandel ER (1994) cAMP contributes to mossy fiber LTP by initiating both a covalently mediated early phase and macromolecular synthesis-dependent late phase. Cell 79:69-79 [PubMed]
Huganir RL, Nicoll RA (2013) AMPARs and synaptic plasticity: the last 25 years. Neuron 80:704-17 [Journal] [PubMed]
Isaac JT, Ashby MC, McBain CJ (2007) The role of the GluR2 subunit in AMPA receptor function and synaptic plasticity. Neuron 54:859-71 [Journal] [PubMed]
Jalil SJ, Sacktor TC, Shouval HZ (2015) Atypical PKCs in memory maintenance: the roles of feedback and redundancy. Learn Mem 22:344-53 [Journal] [PubMed]
Judge ME, Quartermain D (1982) Characteristics of retrograde amnesia following reactivation of memory in mice. Physiol Behav 28:585-90 [PubMed]
Kandel ER (2000) Cellular mechanisms of learning and the biological basis of individuality Principles of neural science. 4th ed :1247-1279
Kandel ER, Dudai Y, Mayford MR (2014) The molecular and systems biology of memory. Cell 157:163-86 [Journal] [PubMed]
Kelly MT, Crary JF, Sacktor TC (2007) Regulation of protein kinase Mzeta synthesis by multiple kinases in long-term potentiation. J Neurosci 27:3439-44 [Journal] [PubMed]
Kelly MT, Yao Y, Sondhi R, Sacktor TC (2007) Actin polymerization regulates the synthesis of PKMzeta in LTP. Neuropharmacology 52:41-5 [Journal] [PubMed]
Kessels HW, Malinow R (2009) Synaptic AMPA receptor plasticity and behavior. Neuron 61:340-50 [Journal] [PubMed]
Krug M, Lössner B, Ott T (1984) Anisomycin blocks the late phase of long-term potentiation in the dentate gyrus of freely moving rats. Brain Res Bull 13:39-42 [PubMed]
Kwapis JL, Jarome TJ, Gilmartin MR, Helmstetter FJ (2012) Intra-amygdala infusion of the protein kinase Mzeta inhibitor ZIP disrupts foreground context fear memory. Neurobiol Learn Mem 98:148-53 [Journal] [PubMed]
Ling DS, Benardo LS, Sacktor TC (2006) Protein kinase Mzeta enhances excitatory synaptic transmission by increasing the number of active postsynaptic AMPA receptors. Hippocampus 16:443-52 [Journal] [PubMed]
Malenka RC, Bear MF (2004) LTP and LTD: an embarrassment of riches. Neuron 44:5-21 [Journal] [PubMed]
Malinow R, Malenka RC (2002) AMPA receptor trafficking and synaptic plasticity. Annu Rev Neurosci 25:103-26 [Journal] [PubMed]
Maren S, Tocco G, Standley S, Baudry M, Thompson RF (1993) Postsynaptic factors in the expression of long-term potentiation (LTP): increased glutamate receptor binding following LTP induction in vivo. Proc Natl Acad Sci U S A 90:9654-8 [PubMed]
Matsuzaki M, Ellis-Davies GC, Nemoto T, Miyashita Y, Iino M, Kasai H (2001) Dendritic spine geometry is critical for AMPA receptor expression in hippocampal CA1 pyramidal neurons. Nat Neurosci 4:1086-92 [Journal] [PubMed]
Mayer ML, Armstrong N (2004) Structure and function of glutamate receptor ion channels. Annu Rev Physiol 66:161-81 [Journal] [PubMed]
Meldrum BS (2000) Glutamate as a neurotransmitter in the brain: review of physiology and pathology. J Nutr 130:1007S-15S [Journal] [PubMed]
Migues PV, Hardt O, Wu DC, Gamache K, Sacktor TC, Wang YT, Nader K (2010) PKMzeta maintains memories by regulating GluR2-dependent AMPA receptor trafficking. Nat Neurosci 13:630-4 [Journal] [PubMed]
Migues PV, Liu L, Archbold GE, Einarsson EÖ, Wong J, Bonasia K, Ko SH, Wang YT, Hardt O (2016) Blocking Synaptic Removal of GluA2-Containing AMPA Receptors Prevents the Natural Forgetting of Long-Term Memories. J Neurosci 36:3481-94 [Journal] [PubMed]
Misanin JR, Miller RR, Lewis DJ (1968) Retrograde amnesia produced by electroconvulsive shock after reactivation of a consolidated memory trace. Science 160:554-5 [PubMed]
Muslimov IA, Nimmrich V, Hernandez AI, Tcherepanov A, Sacktor TC, Tiedge H (2004) Dendritic transport and localization of protein kinase Mzeta mRNA: implications for molecular memory consolidation. J Biol Chem 279:52613-22 [Journal] [PubMed]
Nader K (2003) Memory traces unbound. Trends Neurosci 26:65-72 [Journal] [PubMed]
Nader K, Einarsson EO (2010) Memory reconsolidation: an update. Ann N Y Acad Sci 1191:27-41 [Journal] [PubMed]
Nader K, Schafe GE, Le Doux JE (2000) Fear memories require protein synthesis in the amygdala for reconsolidation after retrieval. Nature 406:722-6 [Journal] [PubMed]
Nguyen PV, Kandel ER (1996) A macromolecular synthesis-dependent late phase of long-term potentiation requiring cAMP in the medial perforant pathway of rat hippocampal slices. J Neurosci 16:3189-98 [PubMed]
Ogasawara H, Kawato M (2010) The protein kinase M? network as a bistable switch to store neuronal memory. BMC Syst Biol 4:181 [Journal] [PubMed]
Osten P, Valsamis L, Harris A, Sacktor TC (1996) Protein synthesis-dependent formation of protein kinase Mzeta in long-term potentiation. J Neurosci 16:2444-51 [PubMed]
Palida SF, Butko MT, Ngo JT, Mackey MR, Gross LA, Ellisman MH, Tsien RY (2015) PKM?, but not PKC?, is rapidly synthesized and degraded at the neuronal synapse. J Neurosci 35:7736-49 [Journal] [PubMed]
Pastalkova E, Serrano P, Pinkhasova D, Wallace E, Fenton AA, Sacktor TC (2006) Storage of spatial information by the maintenance mechanism of LTP. Science 313:1141-4 [Journal] [PubMed]
Plant K, Pelkey KA, Bortolotto ZA, Morita D, Terashima A, McBain CJ, Collingridge GL, Isaac JT (2006) Transient incorporation of native GluR2-lacking AMPA receptors during hippocampal long-term potentiation. Nat Neurosci 9:602-4 [Journal] [PubMed]
Przybyslawski J, Sara SJ (1997) Reconsolidation of memory after its reactivation. Behav Brain Res 84:241-6 [PubMed]
Rao CV,Arkin AP (2003) Stochastic chemical kinetics and the quasi-steady-state assumption: Application to the Gillespie algorithm J Chem Phys 118:4999-5010 [Journal]
Rao-Ruiz P, Rotaru DC, van der Loo RJ, Mansvelder HD, Stiedl O, Smit AB, Spijker S (2011) Retrieval-specific endocytosis of GluA2-AMPARs underlies adaptive reconsolidation of contextual fear. Nat Neurosci 14:1302-8 [Journal] [PubMed]
Raymond CR (2007) LTP forms 1, 2 and 3: different mechanisms for the "long" in long-term potentiation. Trends Neurosci 30:167-75 [Journal] [PubMed]
Ren SQ, Yan JZ, Zhang XY, Bu YF, Pan WW, Yao W, Tian T, Lu W (2013) PKC? is critical in AMPA receptor phosphorylation and synaptic incorporation during LTP. EMBO J 32:1365-80 [Journal] [PubMed]
Rudy JW (2015) Variation in the persistence of memory: An interplay between actin dynamics and AMPA receptors. Brain Res 1621:29-37 [Journal] [PubMed]
Sacktor TC (2008) PKMzeta, LTP maintenance, and the dynamic molecular biology of memory storage. Prog Brain Res 169:27-40 [Journal] [PubMed]
Sacktor TC (2010) PINing for things past. Sci Signal 3:pe9 [Journal] [PubMed]
Sacktor TC (2011) How does PKM? maintain long-term memory? Nat Rev Neurosci 12:9-15 [Journal] [PubMed]
Sacktor TC (2012) Memory maintenance by PKM?--an evolutionary perspective. Mol Brain 5:31 [Journal] [PubMed]
Sacktor TC, Osten P, Valsamis H, Jiang X, Naik MU, Sublette E (1993) Persistent activation of the zeta isoform of protein kinase C in the maintenance of long-term potentiation. Proc Natl Acad Sci U S A 90:8342-6 [PubMed]
Sajikumar S, Navakkode S, Sacktor TC, Frey JU (2005) Synaptic tagging and cross-tagging: the role of protein kinase Mzeta in maintaining long-term potentiation but not long-term depression. J Neurosci 25:5750-6 [Journal] [PubMed]
Sara SJ (2000) Retrieval and reconsolidation: toward a neurobiology of remembering. Learn Mem 7:73-84 [PubMed]
Schafe GE, LeDoux JE (2000) Memory consolidation of auditory pavlovian fear conditioning requires protein synthesis and protein kinase A in the amygdala. J Neurosci 20:RC96 [PubMed]
Schwartz JH,Westbrook GL (2000) The cytology of neurons Principles of neural science :67-87
Serrano P, Yao Y, Sacktor TC (2005) Persistent phosphorylation by protein kinase Mzeta maintains late-phase long-term potentiation. J Neurosci 25:1979-84 [Journal] [PubMed]
Shema R, Sacktor TC, Dudai Y (2007) Rapid erasure of long-term memory associations in the cortex by an inhibitor of PKM zeta. Science 317:951-3 [Journal] [PubMed]
Smolen P, Baxter DA, Byrne JH (2012) Molecular constraints on synaptic tagging and maintenance of long-term potentiation: a predictive model. PLoS Comput Biol 8:e1002620 [Journal] [PubMed]
Sossin WS, Lacaille JC, Castellucci VF, Belleville S (2008) The Essence of Memory. Preface. Prog Brain Res 169:ix-x [Journal] [PubMed]
Sweatt JD (1999) Toward a molecular explanation for long-term potentiation. Learn Mem 6:399-416 [PubMed]
Takumi Y, Matsubara A, Rinvik E, Ottersen OP (1999) The arrangement of glutamate receptors in excitatory synapses. Ann N Y Acad Sci 868:474-82 [PubMed]
Walker DL, Davis M (2002) The role of amygdala glutamate receptors in fear learning, fear-potentiated startle, and extinction. Pharmacol Biochem Behav 71:379-92 [PubMed]
Wanisch K, Wotjak CT (2008) Time course and efficiency of protein synthesis inhibition following intracerebral and systemic anisomycin treatment. Neurobiol Learn Mem 90:485-94 [Journal] [PubMed]
Westmark PR, Westmark CJ, Wang S, Levenson J, O'Riordan KJ, Burger C, Malter JS (2010) Pin1 and PKMzeta sequentially control dendritic protein synthesis. Sci Signal 3:ra18 [Journal] [PubMed]
Xue YX, Luo YX, Wu P, Shi HS, Xue LF, Chen C, Zhu WL, Ding ZB, Bao YP, Shi J, Epstein DH, Shaham Y, Lu L (2012) A memory retrieval-extinction procedure to prevent drug craving and relapse. Science 336:241-5 [Journal] [PubMed]
Yao Y, Kelly MT, Sajikumar S, Serrano P, Tian D, Bergold PJ, Frey JU, Sacktor TC (2008) PKM zeta maintains late long-term potentiation by N-ethylmaleimide-sensitive factor/GluR2-dependent trafficking of postsynaptic AMPA receptors. J Neurosci 28:7820-7 [Journal] [PubMed]
Yu YJ, Chang CH, Gean PW (2013) AMPA receptor endocytosis in the amygdala is involved in the disrupted reconsolidation of Methamphetamine-associated contextual memory. Neurobiol Learn Mem 103:72-81 [Journal] [PubMed]
Yu YJ, Huang CH, Chang CH, Gean PW (2016) Involvement of protein phosphatases in the destabilization of methamphetamine-associated contextual memory. Learn Mem 23:486-93 [Journal] [PubMed]
Zhang Y, Smolen P, Baxter DA, Byrne JH (2010) The sensitivity of memory consolidation and reconsolidation to inhibitors of protein synthesis and kinases: computational analysis. Learn Mem 17:428-39 [Journal] [PubMed]
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