Citation Relationships

Legends: Link to a Model Reference cited by multiple papers


Kager H, Wadman WJ, Somjen GG (2000) Simulated seizures and spreading depression in a neuron model incorporating interstitial space and ion concentrations. J Neurophysiol 84:495-512 [PubMed]

References and models cited by this paper

References and models that cite this paper

Albrecht D, Heinemann U (1989) Low calcium-induced epileptiform activity in hippocampal slices from infant rats. Brain Res Dev Brain Res 48:316-20 [PubMed]
Barchi RL (1995) Molecular pathology of the skeletal muscle sodium channel. Annu Rev Physiol 57:355-85 [Journal] [PubMed]
Basarsky TA, Duffy SN, Andrew RD, MacVicar BA (1998) Imaging spreading depression and associated intracellular calcium waves in brain slices. J Neurosci 18:7189-99 [PubMed]
Basarsky TA, Feighan D, MacVicar BA (1999) Glutamate release through volume-activated channels during spreading depression. J Neurosci 19:6439-45 [PubMed]
Benveniste H, Drejer J, Schousboe A, Diemer NH (1984) Elevation of the extracellular concentrations of glutamate and aspartate in rat hippocampus during transient cerebral ischemia monitored by intracerebral microdialysis. J Neurochem 43:1369-74 [PubMed]
Borck C, Jefferys JG (1999) Seizure-like events in disinhibited ventral slices of adult rat hippocampus. J Neurophysiol 82:2130-42 [Journal] [PubMed]
Borg-graham L (1999) Interpretations of data and mechanisms for hippocampal pyramidal cell models Cerebral Cortex cortical Models, Jones E:Ulinski P:Peters A, ed. pp.19
Brown TH, Fricke RA, Perkel DH (1981) Passive electrical constants in three classes of hippocampal neurons. J Neurophysiol 46:812-27 [Journal] [PubMed]
Bure J, Bureov O, Kivnek J (1974) The Mechanism And Applications Of Leos Spreading Depression Of Electroencephalographic Activity
Bures J, Buresová O, Krivánek J (1984) The meaning and significance of Leão's spreading depression. An Acad Bras Cienc 56:385-400 [PubMed]
Cannon RC, Turner DA, Pyapali GK, Wheal HV (1998) An on-line archive of reconstructed hippocampal neurons. J Neurosci Methods 84:49-54 [PubMed]
Crowder JM, Croucher MJ, Bradford HF, Collins JF (1987) Excitatory amino acid receptors and depolarization-induced Ca2+ influx into hippocampal slices. J Neurochem 48:1917-24 [PubMed]
Czéh G, Aitken PG, Somjen GG (1993) Membrane currents in CA1 pyramidal cells during spreading depression (SD) and SD-like hypoxic depolarization. Brain Res 632:195-208 [PubMed]
Dietzel I, Heinemann U (1986) Dynamic variations of the brain cell microenvironment in relation to neuronal hyperactivity. Ann N Y Acad Sci 481:72-86 [PubMed]
do Carmo RJ, Martins-Ferreira H (1984) Spreading depression of Leão probed with ion-selective microelectrodes in isolated chick retina. An Acad Bras Cienc 56:401-21 [PubMed]
Drejer J, Benveniste H, Diemer NH, Schousboe A (1985) Cellular origin of ischemia-induced glutamate release from brain tissue in vivo and in vitro. J Neurochem 45:145-51 [PubMed]
Dudek FE, Obenaus A, Tasker JG (1990) Osmolality-induced changes in extracellular volume alter epileptiform bursts independent of chemical synapses in the rat: importance of non-synaptic mechanisms in hippocampal epileptogenesis. Neurosci Lett 120:267-70 [PubMed]
Fertziger AP, Ranck JB (1970) Potassium accumulation in interstitial space during epileptiform seizures. Exp Neurol 26:571-85 [PubMed]
FRANKENHAEUSER B, HODGKIN AL (1956) The after-effects of impulses in the giant nerve fibres of Loligo. J Physiol 131:341-76 [PubMed]
Fraser DD, MacVicar BA (1996) Cholinergic-dependent plateau potential in hippocampal CA1 pyramidal neurons. J Neurosci 16:4113-28 [PubMed]
French CR, Sah P, Buckett KJ, Gage PW (1990) A voltage-dependent persistent sodium current in mammalian hippocampal neurons. J Gen Physiol 95:1139-57 [PubMed]
Fujikawa DG, Kim JS, Daniels AH, Alcaraz AF, Sohn TB (1996) In vivo elevation of extracellular potassium in the rat amygdala increases extracellular glutamate and aspartate and damages neurons. Neuroscience 74:695-706 [PubMed]
Fujimura N, Tanaka E, Yamamoto S, Shigemori M, Higashi H (1997) Contribution of ATP-sensitive potassium channels to hypoxic hyperpolarization in rat hippocampal CA1 neurons in vitro. J Neurophysiol 77:378-85 [Journal] [PubMed]
Fujiwara N, Higashi H, Shimoji K, Yoshimura M (1987) Effects of hypoxia on rat hippocampal neurones in vitro. J Physiol 384:131-51 [PubMed]
GLOOR P, SPERTI L, VERA CL (1964) A CONSIDERATION OF FEEDBACK MECHANISMS IN THE GENESIS AND MAINTENANCE OF HIPPOCAMPAL SEIZURE ACTIVITY. Epilepsia 5:213-38 [PubMed]
GLOOR P, VERA CL, SPERTI L, RAY SN (1961) Investigations on the mechanism of epileptic discharge in the hippocampus. (A preliminary report). Epilepsia 2:42-62 [PubMed]
GRAFSTEIN B (1956) Mechanism of spreading cortical depression. J Neurophysiol 19:154-71 [Journal] [PubMed]
Grafstein B (1963) Neuronal release of potassium during spreading depression Brain Function Cortical Excitability And Steady Potentials, Brazier MAB, ed. pp.87
GREEN JD (1964) THE HIPPOCAMPUS. Physiol Rev 44:561-608 [Journal] [PubMed]
Hammarstrom AK, Gage PW (1998) Inhibition of oxidative metabolism increases persistent sodium current in rat CA1 hippocampal neurons. J Physiol 510 ( Pt 3):735-41 [PubMed]
Hansen AJ, Lauritzen M (1984) The role of spreading depression in acute brain disorders. An Acad Bras Cienc 56:457-79 [PubMed]
Hansen AJ, Olsen CE (1980) Brain extracellular space during spreading depression and ischemia. Acta Physiol Scand 108:355-65 [Journal] [PubMed]
Hansen AJ, Zeuthen T (1981) Extracellular ion concentrations during spreading depression and ischemia in the rat brain cortex. Acta Physiol Scand 113:437-45 [Journal] [PubMed]
Heinemann U, Gutnick MJ (1979) Relation between extracellular potassium concentration and neuronal activities in cat thalamus (VPL) during projection of cortical epileptiform discharge. Electroencephalogr Clin Neurophysiol 47:345-7 [PubMed]
Heinemann U, Lux HD (1975) Undershoots following stimulus-induced rises of extracellular potassium concentration in cerebral cortex of cat. Brain Res 93:63-76 [PubMed]
Heinemann U, Lux HD (1977) Ceiling of stimulus induced rises in extracellular potassium concentration in the cerebral cortex of cat. Brain Res 120:231-49 [PubMed]
Heinemann U, Lux HD, Gutnick MJ (1978) Changes in extracellular free calcium and potassium activity in the somatosensory cortex of cats Abnormal Neuronal Discharges, Chalazonitis N:Boisson M, ed. pp.329
Hernándéz-Cáceres J, Macias-González R, Brozek G, Bures J (1987) Systemic ketamine blocks cortical spreading depression but does not delay the onset of terminal anoxic depolarization in rats. Brain Res 437:360-4 [PubMed]
Herreras O, Somjen GG (1993) Analysis of potential shifts associated with recurrent spreading depression and prolonged unstable spreading depression induced by microdialysis of elevated K+ in hippocampus of anesthetized rats. Brain Res 610:283-94 [PubMed]
Herreras O, Somjen GG (1993) Propagation of spreading depression among dendrites and somata of the same cell population. Brain Res 610:276-82 [PubMed]
Hestrin S, Nicoll RA, Perkel DJ, Sah P (1990) Analysis of excitatory synaptic action in pyramidal cells using whole-cell recording from rat hippocampal slices. J Physiol 422:203-25 [PubMed]
Hille B (1992) Potassium channels and chloride channels Ionic Channels of Excitable Membrane, Hille B, ed. pp.115
Hines ML, Carnevale NT (1997) The NEURON simulation environment. Neural Comput 9:1179-209 [PubMed]
Hoffman EP, Lehmann-Horn F, Rüdel R (1995) Overexcited or inactive: ion channels in muscle disease. Cell 80:681-6 [PubMed]
Jing J, Aitken PG, Somjen GG (1994) Interstitial volume changes during spreading depression (SD) and SD-like hypoxic depolarization in hippocampal tissue slices. J Neurophysiol 71:2548-51 [Journal] [PubMed]
Kawasaki H, Palmieri C, Avoli M (1999) Muscarinic receptor activation induces depolarizing plateau potentials in bursting neurons of the rat subiculum. J Neurophysiol 82:2590-601 [Journal] [PubMed]
Kraig RP, Nicholson C (1978) Extracellular ionic variations during spreading depression. Neuroscience 3:1045-59 [PubMed]
Leo AAP (1944) Spreading depression of activity in the cerebral cortex J Neurophysiol 7:359-390 [Journal]
Luger P (1991) Electrogenic Ion Pumps
Magee JC, Johnston D (1995) Characterization of single voltage-gated Na+ and Ca2+ channels in apical dendrites of rat CA1 pyramidal neurons. J Physiol 487:67-90 [PubMed]
Marrannes R, Prins DEE, Fransen J, Clincke G (1993) Neuropharmcology of spreading depression Migraine: Basic Mechanisms And Treatment, Lehmenkhler A:Grotemeyer K-H:Tegtmeier F, ed. pp.431
Marrannes R, Prins DEE, Willems R, Wauquier A (1988) NMDA antagonists inhibit cortical spreading depression, but accelerate the onset of neuronal depolarization induced by asphyxia Mechanisms Of Cerebral Hypoxia And Stroke, Somjen G, ed. pp.303
MARSHALL WH (1959) Spreading cortical depression of Leao. Physiol Rev 39:239-79 [Journal] [PubMed]
Mazel T, Simonová Z, Syková E (1998) Diffusion heterogeneity and anisotropy in rat hippocampus. Neuroreport 9:1299-304 [PubMed]
McBain CJ, Traynelis SF, Dingledine R (1990) Regional variation of extracellular space in the hippocampus. Science 249:674-7 [PubMed]
Mittmann T, Linton SM, Schwindt P, Crill W (1997) Evidence for persistent Na+ current in apical dendrites of rat neocortical neurons from imaging of Na+-sensitive dye. J Neurophysiol 78:1188-92 [Journal] [PubMed]
Müller M (2000) Effects of chloride transport inhibition and chloride substitution on neuron function and on hypoxic spreading-depression-like depolarization in rat hippocampal slices. Neuroscience 97:33-45 [PubMed]
Müller M, Somjen GG (1998) Inhibition of major cationic inward currents prevents spreading depression-like hypoxic depolarization in rat hippocampal tissue slices. Brain Res 812:1-13 [PubMed]
Müller M, Somjen GG (2000) Na(+) and K(+) concentrations, extra- and intracellular voltages, and the effect of TTX in hypoxic rat hippocampal slices. J Neurophysiol 83:735-45 [Journal] [PubMed]
Nicholson C (1984) Comparative neurophysiology of spreading depression in the cerebellum. An Acad Bras Cienc 56:481-94 [PubMed]
Pérez-Pinzón MA, Tao L, Nicholson C (1995) Extracellular potassium, volume fraction, and tortuosity in rat hippocampal CA1, CA3, and cortical slices during ischemia. J Neurophysiol 74:565-73 [Journal] [PubMed]
Poolos NP, Kocsis JD (1990) Elevated extracellular potassium concentration enhances synaptic activation of N-methyl-D-aspartate receptors in hippocampus. Brain Res 508:7-12 [PubMed]
Pyapali GK, Sik A, Penttonen M, Buzsaki G, Turner DA (1998) Dendritic properties of hippocampal CA1 pyramidal neurons in the rat: intracellular staining in vivo and in vitro. J Comp Neurol 391:335-52 [PubMed]
Rall W, Burke RE, Holmes WR, Jack JJ, Redman SJ, Segev I (1992) Matching dendritic neuron models to experimental data. Physiol Rev 72:S159-86 [Journal] [PubMed]
Reggia JA, Montgomery D (1996) A computational model of visual hallucinations in migraine. Comput Biol Med 26:133-41 [PubMed]
Revett K, Ruppin E, Goodall S, Reggia JA (1998) Spreading depression in focal ischemia: a computational study. J Cereb Blood Flow Metab 18:998-1007 [Journal] [PubMed]
Sah P, Gibb AJ, Gage PW (1988) The sodium current underlying action potentials in guinea pig hippocampal CA1 neurons. J Gen Physiol 91:373-98 [PubMed]
Schwartzkroin PA (1984) Epileptogenesis in the immature central nervous system Electrophysiology Of Epilepsy, Schwartzkroin PA:Wheal HV, ed. pp.389
Schwartzkroin PA, Mueller AL (1987) Electrophysiology of hippocampal neurons Cereb Cortex 6:295-343
Shapiro BE (1999) Leo's spreading depression and gap junctions: an electro-diffusion model of the voltage shift, ionic movement and osmotic volume changes Soc Neurosci Abstr 25:315
Snow RW, Taylor CP, Dudek FE (1983) Electrophysiological and optical changes in slices of rat hippocampus during spreading depression. J Neurophysiol 50:561-72 [Journal] [PubMed]
Somjen GG (1987) Functions of glial cells in the cerebral cortex Cereb Cortex 6:1-39
Somjen GG (1995) Electrophysiology of mammalian glial cells in situ Neuroglial Cells, Kettenmann H:Ransom BR, ed. pp.319
Somjen GG (2000) Intracellular fluorescence and elevated [K+]o potentiate persistent sodium current in isolated hippocampal neurons Faseb J 14:107
Somjen GG, Aitken PG (1984) The ionic and metabolic responses associated with neuronal depression of Leão's type in cerebral cortex and in hippocampal formation. An Acad Bras Cienc 56:495-504 [PubMed]
Somjen GG, Aitken PG, Giacchino JL, McNamara JO (1985) Sustained potential shifts and paroxysmal discharges in hippocampal formation. J Neurophysiol 53:1079-97 [Journal] [PubMed]
Somjen GG, Aitken PG, Giacchino JL, McNamara JO (1986) Interstitial ion concentrations and paroxysmal discharges in hippocampal formation and spinal cord. Adv Neurol 44:663-80 [PubMed]
Somjen GG, Giacchino JL (1985) Potassium and calcium concentrations in interstitial fluid of hippocampal formation during paroxysmal responses. J Neurophysiol 53:1098-108 [Journal] [PubMed]
Somjen GG, Kager H, Wadman WJ (In press) Simulated seizures and spreading depression 2nd Meet Fed Eur Neurosci Soc
Szerb JC (1991) Glutamate release and spreading depression in the fascia dentata in response to microdialysis with high K+: role of glia. Brain Res 542:259-65 [PubMed]
Traub RD, Jefferys JG, Miles R, Whittington MA, Tóth K (1994) A branching dendritic model of a rodent CA3 pyramidal neurone. J Physiol 481 ( Pt 1):79-95 [PubMed]
Tuckwell HC, Miura RM (1978) A mathematical model for spreading cortical depression. Biophys J 23:257-76 [Journal] [PubMed]
Van Harreveld A (1978) Two mechanisms for spreading depression in the chicken retina. J Neurobiol 9:419-31 [Journal] [PubMed]
Van Harreveld A, Fifková E (1970) Glutamate release from the retina during spreading depression. J Neurobiol 2:13-29 [Journal] [PubMed]
VAN HARREVELD A, STAMM JS (1953) Spreading cortical convulsions and depressions. J Neurophysiol 16:352-66 [Journal] [PubMed]
Vreugdenhil M, Faas GC, Wadman WJ (1998) Sodium currents in isolated rat CA1 neurons after kindling epileptogenesis. Neuroscience 86:99-107 [PubMed]
Wadman WJ, Juta AJ, Kamphuis W, Somjen GG (1992) Current source density of sustained potential shifts associated with electrographic seizures and with spreading depression in rat hippocampus. Brain Res 570:85-91 [PubMed]
Young JN, Somjen GG (1992) Suppression of presynaptic calcium currents by hypoxia in hippocampal tissue slices. Brain Res 573:70-6 [PubMed]
Barreto E, Cressman JR (2011) Ion concentration dynamics as a mechanism for neuronal bursting. J Biol Phys 37:361-73 [Journal] [PubMed]
   Ion concentration dynamics as a mechanism for neuronal bursting (Barreto & Cressman 2011) [Model]
Buchin A, Chizhov A, Huberfeld G, Miles R, Gutkin BS (2016) Reduced Efficacy of the KCC2 Cotransporter Promotes Epileptic Oscillations in a Subiculum Network Model. J Neurosci 36:11619-11633 [Journal] [PubMed]
   Subiculum network model with dynamic chloride/potassium homeostasis (Buchin et al 2016) [Model]
Carnevale NT, Morse TM (1996-2009) Research reports that have used NEURON Web published citations at the NEURON website [Journal]
Conte C, Lee R, Sarkar M, Terman D (2018) A mathematical model of recurrent spreading depolarizations. J Comput Neurosci 44:203-217 [Journal] [PubMed]
   A model for recurrent spreading depolarizations (Conte et al. 2017) [Model]
Cressman JR, Ullah G, Ziburkus J, Schiff SJ, Barreto E (2009) The influence of sodium and potassium dynamics on excitability, seizures, and the stability of persistent states: I. Single neuron dynamics. J Comput Neurosci 26:159-70 [Journal] [PubMed]
   Single neuron with dynamic ion concentrations (Cressman et al. 2009) [Model]
Dahlem MA, Schumacher J, Hübel N (2014) Linking a genetic defect in migraine to spreading depression in a computational model. PeerJ 2:e379 [Journal] [PubMed]
   Spreading depression model for FHM3 with Nav1.1 mutation (Dahlem et al. 2014) [Model]
Gentiletti D, Suffczynski P, Gnatkovsky V, de Curtis M (2017) Changes of Ionic Concentrations During Seizure Transitions - A Modeling Study. Int J Neural Syst 27:1750004 [Journal] [PubMed]
   Changes of ionic concentrations during seizure transitions (Gentiletti et al. 2016) [Model]
Hines ML, Carnevale NT (2003) Personal Communication of NEURON bibliography
Ho ECY, Truccolo W (2016) Interaction between Synaptic Inhibition and Glial-Potassium Dynamics leads to Diverse Seizure Transition Modes in Biophysical Models of Human Focal Seizures J Comput Neurosci [Journal]
   Inhibition and glial-K+ interaction leads to diverse seizure transition modes (Ho & Truccolo 2016) [Model]
Hübel N, Andrew RD, Ullah G (2016) Large extracellular space leads to neuronal susceptibility to ischemic injury in a Na+/K+ pumps-dependent manner. J Comput Neurosci 40:177-92 [Journal] [PubMed]
   Anoxic depolarization, recovery: effect of brain regions and extracellular space (Hubel et al. 2016) [Model]
Hübel N, Dahlem MA (2014) Dynamics from seconds to hours in Hodgkin-Huxley model with time-dependent ion concentrations and buffer reservoirs. PLoS Comput Biol 10:e1003941 [Journal] [PubMed]
   Hodgkin-Huxley with dynamic ion concentrations (Hubel and Dahlem, 2014) [Model]
Hübel N, Hosseini-Zare MS, Žiburkus J, Ullah G (2017) The role of glutamate in neuronal ion homeostasis: A case study of spreading depolarization. PLoS Comput Biol 13:e1005804 [Journal] [PubMed]
   The role of glutamate in neuronal ion homeostasis: spreading depolarization (Hubel et al 2017) [Model]
Joos B, Barlow BM, Morris CE (2018) Calculating the Consequences of Left-Shifted Nav Channel Activity in Sick Excitable Cells. Handb Exp Pharmacol 246:401-422 [Journal] [PubMed]
   Calculating the consequences of left-shifted Nav channel activity in sick cells (Joos et al 2018) [Model]
Kager H, Wadman WJ, Somjen GG (2002) Conditions for the triggering of spreading depression studied with computer simulations. J Neurophysiol 88:2700-12 [Journal] [PubMed]
Kager H, Wadman WJ, Somjen GG (2007) Seizure-like afterdischarges simulated in a model neuron. J Comput Neurosci 22:105-28 [Journal] [PubMed]
Krishnan GP, Filatov G, Shilnikov A, Bazhenov M (2015) Electrogenic properties of the Na?/K? ATPase control transitions between normal and pathological brain states. J Neurophysiol 113:3356-74 [Journal] [PubMed]
   Single cell model with variable ion concentrations and Na+/K+ ATPase (Krishnan et al. 2015) [Model]
Lewin N, Aksay E, Clancy CE (2012) Computational modeling reveals dendritic origins of GABA(A)-mediated excitation in CA1 pyramidal neurons. PLoS One 7:e47250 [Journal] [PubMed]
   Paradoxical GABA-mediated excitation (Lewin et al. 2012) [Model]
Øyehaug L, Østby I, Lloyd CM, Omholt SW, Einevoll GT (2012) Dependence of spontaneous neuronal firing and depolarisation block on astroglial membrane transport mechanisms. J Comput Neurosci 32:147-65 [Journal] [PubMed]
   Dependence of neuronal firing on astroglial membrane transport mechanisms (Oyehaug et al 2012) [Model]
Somjen GG (2001) Mechanisms of spreading depression and hypoxic spreading depression-like depolarization. Physiol Rev 81:1065-96 [Journal] [PubMed]
Somjen GG, Kager H, Wadman WJ (2008) Computer simulations of neuron-glia interactions mediated by ion flux. J Comput Neurosci 25:349-65 [Journal] [PubMed]
   Computer simulations of neuron-glia interactions mediated by ion flux (Somjen et al. 2008) [Model]
Somjen GG, Kager H, Wadman WJ (2009) Calcium sensitive non-selective cation current promotes seizure-like discharges and spreading depression in a model neuron. J Comput Neurosci 26:139-47 [Journal] [PubMed]
Ullah G, Cressman JR, Barreto E, Schiff SJ (2009) The influence of sodium and potassium dynamics on excitability, seizures, and the stability of persistent states. II. Network and glial dynamics. J Comput Neurosci 26:171-83 [Journal] [PubMed]
   Network model with dynamic ion concentrations (Ullah et al. 2009) [Model]
(113 refs)