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Luo CH, Rudy Y (1994) A dynamic model of the cardiac ventricular action potential. II. Afterdepolarizations, triggered activity, and potentiation. Circ Res 74:1097-113 [PubMed]

   Ventricular cell model (Luo Rudy dynamic model) (Luo Rudy 1994) used in (Wang et al 2006) (XPP)

   Ventricular cell model (Guinea-pig-type) (Luo, Rudy 1991, +11 other papers!) (C++)

References and models cited by this paper

References and models that cite this paper

Aronson RS (1981) Afterpotentials and triggered activity in hypertrophied myocardium from rats with renal hypertension. Circ Res 48:720-7 [PubMed]
Beeler GW, Reuter H (1977) Reconstruction of the action potential of ventricular myocardial fibres. J Physiol 268:177-210 [Journal] [PubMed]
   Mammalian Ventricular Cell (Beeler and Reuter 1977) [Model]
Berlin JR, Cannell MB, Lederer WJ (1989) Cellular origins of the transient inward current in cardiac myocytes. Role of fluctuations and waves of elevated intracellular calcium. Circ Res 65:115-26 [PubMed]
Cannell MB, Lederer WJ (1986) The arrhythmogenic current ITI in the absence of electrogenic sodium-calcium exchange in sheep cardiac Purkinje fibres. J Physiol 374:201-19 [PubMed]
Capogrossi MC, Houser SR, Bahinski A, Lakatta EG (1987) Synchronous occurrence of spontaneous localized calcium release from the sarcoplasmic reticulum generates action potentials in rat cardiac ventricular myocytes at normal resting membrane potential. Circ Res 61:498-503 [PubMed]
Capogrossi MC, Stern MD, Spurgeon HA, Lakatta EG (1988) Spontaneous Ca2+ release from the sarcoplasmic reticulum limits Ca2+-dependent twitch potentiation in individual cardiac myocytes. A mechanism for maximum inotropy in the myocardium. J Gen Physiol 91:133-55 [PubMed]
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Cranefield PF, Aronson RS (1988) Cardiac Arrhythmias: The Role of Triggered Activity and Other Mechanisms
Damiano BP, Rosen MR (1984) Effects of pacing on triggered activity induced by early afterdepolarizations. Circulation 69:1013-25 [PubMed]
Doerr T, Denger R, Doerr A, Trautwein W (1990) Ionic currents contributing to the action potential in single ventricular myocytes of the guinea pig studied with action potential clamp. Pflugers Arch 416:230-7 [PubMed]
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Fabiato A (1985) Simulated calcium current can both cause calcium loading in and trigger calcium release from the sarcoplasmic reticulum of a skinned canine cardiac Purkinje cell. J Gen Physiol 85:291-320 [PubMed]
Fedida D, Noble D, Rankin AC, Spindler AJ (1987) The arrhythmogenic transient inward current iTI and related contraction in isolated guinea-pig ventricular myocytes. J Physiol 392:523-42 [PubMed]
Giles W, Shimoni Y (1989) Comparison of sodium-calcium exchanger and transient inward currents in single cells from rabbit ventricle. J Physiol 417:465-81 [PubMed]
Hoffman BF, Rosen MR (1981) Cellular mechanisms for cardiac arrhythmias. Circ Res 49:1-15 [PubMed]
Isenberg G, Klöckner U (1982) Calcium currents of isolated bovine ventricular myocytes are fast and of large amplitude. Pflugers Arch 395:30-41 [PubMed]
January CT, Riddle JM (1989) Early afterdepolarizations: mechanism of induction and block. A role for L-type Ca2+ current. Circ Res 64:977-90 [PubMed]
Kass RS, Tsien RW, Weingart R (1978) Ionic basis of transient inward current induced by strophanthidin in cardiac Purkinje fibres. J Physiol 281:209-26 [PubMed]
Lipp P, Pott L (1988) Transient inward current in guinea-pig atrial myocytes reflects a change of sodium-calcium exchange current. J Physiol 397:601-30 [PubMed]
Luo CH, Rudy Y (1991) A model of the ventricular cardiac action potential. Depolarization, repolarization, and their interaction. Circ Res 68:1501-26 [PubMed]
   Ventricular cell model (Guinea-pig-type) (Luo, Rudy 1991, +11 other papers!) (C++) [Model]
   Cardiac action potential based on Luo-Rudy phase 1 model (Luo and Rudy 1991), (Wu 2004) [Model]
Luo CH, Rudy Y (1994) A dynamic model of the cardiac ventricular action potential. I. Simulations of ionic currents and concentration changes. Circ Res 74:1071-96 [PubMed]
   Ventricular cell model (Guinea-pig-type) (Luo, Rudy 1991, +11 other papers!) (C++) [Model]
Marban E, Robinson SW, Wier WG (1986) Mechanisms of arrhythmogenic delayed and early afterdepolarizations in ferret ventricular muscle. J Clin Invest 78:1185-92 [Journal] [PubMed]
Matsuda H, Noma A, Kurachi Y, Irisawa H (1982) Transient depolarization and spontaneous voltage fluctuations in isolated single cells from guinea pig ventricles. Calcium-mediated membrane potential fluctuations. Circ Res 51:142-51 [PubMed]
Mulder BJ, de Tombe PP, ter Keurs HE (1989) Spontaneous and propagated contractions in rat cardiac trabeculae. J Gen Physiol 93:943-61 [PubMed]
Nordin C, Aronson RS (1987) Interaction of oscillatory currents andsteady-state membrane conductance in isolated cardiac myocytes:experimental description and preliminary modeling of syncytialeffects Activation, Metabolism and Perfusion of the Heart, Sideman S:Beyar R, ed. pp.151
Priori SG, Corr PB (1990) Mechanisms underlying early and delayed afterdepolarizations induced by catecholamines. Am J Physiol 258:H1796-805 [Journal] [PubMed]
Rosen MR (1990) The concept of afterdepolarization Cardiac Electrophysiology: A Textbook, Rosen MR:Janse MJ:Wit AL, ed. pp.267
Stern MD, Capogrossi MC, Lakatta EG (1988) Spontaneous calcium release from the sarcoplasmic reticulum in myocardial cells: mechanisms and consequences. Cell Calcium 9:247-56 [PubMed]
Vassalle M (1990) Overdrive suppression and overdrive excitation Cardiac Electrophysiology: A Textbook, Rosen MR:Janse MJ:Wit AL, ed. pp.175
Wier WG, Yue DT (1986) Intracellular calcium transients underlying the short-term force-interval relationship in ferret ventricular myocardium. J Physiol 376:507-30 [PubMed]
Yue DT, Burkhoff D, Franz MR, Hunter WC, Sagawa K (1985) Postextrasystolic potentiation of the isolated canine left ventricle. Relationship to mechanical restitution. Circ Res 56:340-50 [PubMed]
Clancy CE, Rudy Y (1999) Linking a genetic defect to its cellular phenotype in a cardiac arrhythmia. Nature 400:566-9 [Journal] [PubMed]
   Ventricular cell model (Guinea-pig-type) (Luo, Rudy 1991, +11 other papers!) (C++) [Model]
Faber GM, Rudy Y (2000) Action potential and contractility changes in [Na(+)](i) overloaded cardiac myocytes: a simulation study. Biophys J 78:2392-404 [Journal] [PubMed]
   Ventricular cell model (Guinea-pig-type) (Luo, Rudy 1991, +11 other papers!) (C++) [Model]
Luo CH, Rudy Y (1994) A dynamic model of the cardiac ventricular action potential. I. Simulations of ionic currents and concentration changes. Circ Res 74:1071-96 [PubMed]
   Ventricular cell model (Guinea-pig-type) (Luo, Rudy 1991, +11 other papers!) (C++) [Model]
Shaw RM, Rudy Y (1997) Electrophysiologic effects of acute myocardial ischemia: a theoretical study of altered cell excitability and action potential duration. Cardiovasc Res 35:256-72 [PubMed]
   Ventricular cell model (Guinea-pig-type) (Luo, Rudy 1991, +11 other papers!) (C++) [Model]
Viswanathan PC, Rudy Y (1999) Pause induced early afterdepolarizations in the long QT syndrome: a simulation study. Cardiovasc Res 42:530-42 [PubMed]
   Ventricular cell model (Guinea-pig-type) (Luo, Rudy 1991, +11 other papers!) (C++) [Model]
Viswanathan PC, Shaw RM, Rudy Y (1999) Effects of IKr and IKs heterogeneity on action potential duration and its rate dependence: a simulation study. Circulation 99:2466-74 [PubMed]
   Ventricular cell model (Guinea-pig-type) (Luo, Rudy 1991, +11 other papers!) (C++) [Model]
Zeng J, Laurita KR, Rosenbaum DS, Rudy Y (1995) Two components of the delayed rectifier K+ current in ventricular myocytes of the guinea pig type. Theoretical formulation and their role in repolarization. Circ Res 77:140-52 [PubMed]
   Ventricular cell model (Guinea-pig-type) (Luo, Rudy 1991, +11 other papers!) (C++) [Model]
Zeng J, Rudy Y (1995) Early afterdepolarizations in cardiac myocytes: mechanism and rate dependence. Biophys J 68:949-64 [Journal] [PubMed]
   Ventricular cell model (Guinea-pig-type) (Luo, Rudy 1991, +11 other papers!) (C++) [Model]
(40 refs)