Citation Relationships

Legends: Link to a Model Reference cited by multiple papers

Viswanathan PC, Rudy Y (1999) Pause induced early afterdepolarizations in the long QT syndrome: a simulation study. Cardiovasc Res 42:530-42 [PubMed]

   Ventricular cell model (Guinea-pig-type) (Luo, Rudy 1991, +11 other papers!) (C++)

References and models cited by this paper

References and models that cite this paper

Ackerman MJ (1998) The long QT syndrome: ion channel diseases of the heart. Mayo Clin Proc 73:250-69 [Journal] [PubMed]
An RH, Wang XL, Kerem B, Benhorin J, Medina A, Goldmit M, Kass RS (1998) Novel LQT-3 mutation affects Na+ channel activity through interactions between alpha- and beta1-subunits. Circ Res 83:141-6 [PubMed]
Antzelevitch C, Sicouri S (1994) Clinical relevance of cardiac arrhythmias generated by afterdepolarizations. Role of M cells in the generation of U waves, triggered activity and torsade de pointes. J Am Coll Cardiol 23:259-77 [PubMed]
Bennett PB, Yazawa K, Makita N, George AL (1995) Molecular mechanism for an inherited cardiac arrhythmia. Nature 376:683-5 [Journal] [PubMed]
Bers DM (1993) Control of cardiac contraction by SR Ca release and sarcolemmal Ca fluxes Excitation contraction coupling and cardiac contractile force, Bers DM, ed. pp.149
Brugada P, Wellens HJ (1985) Early afterdepolarizations: role in conduction block, "prolonged repolarization-dependent reexcitation," and tachyarrhythmias in the human heart. Pacing Clin Electrophysiol 8:889-96 [PubMed]
Burashnikov A, Antzelevitch C (1998) Acceleration-induced action potential prolongation and early afterdepolarizations. J Cardiovasc Electrophysiol 9:934-48 [PubMed]
Chandra R, Starmer CF, Grant AO (1998) Multiple effects of KPQ deletion mutation on gating of human cardiac Na+ channels expressed in mammalian cells. Am J Physiol 274:H1643-54 [Journal] [PubMed]
Compton SJ, Lux RL, Ramsey MR, Strelich KR, Sanguinetti MC, Green LS, Keating MT, Mason JW (1996) Genetically defined therapy of inherited long-QT syndrome. Correction of abnormal repolarization by potassium. Circulation 94:1018-22 [PubMed]
Cranefield FP, Aronson RS (1988) The long QT syndrome and Torsade de Pointes Cardiac arrhythmias: the role of triggered activity and other mechanisms Futura, Cranefield FP:Aronson RS, ed. pp.553
Deal KK, England SK, Tamkun MM (1996) Molecular physiology of cardiac potassium channels. Physiol Rev 76:49-67 [Journal] [PubMed]
Dessertenne F (1966) [Ventricular tachycardia with 2 variable opposing foci]. Arch Mal Coeur Vaiss 59:263-72 [PubMed]
Drouin E, Charpentier F, Gauthier C, Laurent K, Le Marec H (1995) Electrophysiologic characteristics of cells spanning the left ventricular wall of human heart: evidence for presence of M cells. J Am Coll Cardiol 26:185-92 [PubMed]
el-Sherif N, Caref EB, Yin H, Restivo M (1996) The electrophysiological mechanism of ventricular arrhythmias in the long QT syndrome. Tridimensional mapping of activation and recovery patterns. Circ Res 79:474-92 [PubMed]
Eldar M, Griffin JC, Van Hare GF, Witherell C, Bhandari A, Benditt D, Scheinman MM (1992) Combined use of beta-adrenergic blocking agents and long-term cardiac pacing for patients with the long QT syndrome. J Am Coll Cardiol 20:830-7 [PubMed]
Habbab MA, el-Sherif N (1990) Drug-induced torsades de pointes: role of early afterdepolarizations and dispersion of repolarization. Am J Med 89:241-6 [PubMed]
Jackman WM, Friday KJ, Anderson JL, Aliot EM, Clark M, Lazzara R (1988) The long QT syndromes: a critical review, new clinical observations and a unifying hypothesis. Prog Cardiovasc Dis 31:115-72 [PubMed]
January CT, Riddle JM (1989) Early afterdepolarizations: mechanism of induction and block. A role for L-type Ca2+ current. Circ Res 64:977-90 [PubMed]
Jurkiewicz NK, Sanguinetti MC (1993) Rate-dependent prolongation of cardiac action potentials by a methanesulfonanilide class III antiarrhythmic agent. Specific block of rapidly activating delayed rectifier K+ current by dofetilide. Circ Res 72:75-83 [PubMed]
Kay GN, Plumb VJ, Arciniegas JG, Henthorn RW, Waldo AL (1983) Torsade de pointes: the long-short initiating sequence and other clinical features: observations in 32 patients. J Am Coll Cardiol 2:806-17 [PubMed]
Laurita KR, Girouard SD, Rosenbaum DS (1996) Modulation of ventricular repolarization by a premature stimulus. Role of epicardial dispersion of repolarization kinetics demonstrated by optical mapping of the intact guinea pig heart. Circ Res 79:493-503 [PubMed]
Leclercq JF, Maisonblanche P, Cauchemez B, Coumel P (1988) Respective role of sympathetic tone and of cardiac pauses in the genesis of 62 cases of ventricular fibrillation recorded during Holter monitoring. Eur Heart J 9:1276-83 [PubMed]
Liu DW, Antzelevitch C (1995) Characteristics of the delayed rectifier current (IKr and IKs) in canine ventricular epicardial, midmyocardial, and endocardial myocytes. A weaker IKs contributes to the longer action potential of the M cell. Circ Res 76:351-65 [PubMed]
Locati EH, Maison-Blanche P, Dejode P, Cauchemez B, Coumel P (1995) Spontaneous sequences of onset of torsade de pointes in patients with acquired prolonged repolarization: quantitative analysis of Holter recordings. J Am Coll Cardiol 25:1564-75 [PubMed]
Luo CH, Rudy Y (1994) A dynamic model of the cardiac ventricular action potential. II. Afterdepolarizations, triggered activity, and potentiation. Circ Res 74:1097-113 [PubMed]
   Ventricular cell model (Luo Rudy dynamic model) (Luo Rudy 1994) used in (Wang et al 2006) (XPP) [Model]
   Ventricular cell model (Guinea-pig-type) (Luo, Rudy 1991, +11 other papers!) (C++) [Model]
Luo CH, Rudy Y (1994) A dynamic model of the cardiac ventricular action potential. I. Simulations of ionic currents and concentration changes. Circ Res 74:1071-96 [PubMed]
   Ventricular cell model (Guinea-pig-type) (Luo, Rudy 1991, +11 other papers!) (C++) [Model]
Marban E, Robinson SW, Wier WG (1986) Mechanisms of arrhythmogenic delayed and early afterdepolarizations in ferret ventricular muscle. J Clin Invest 78:1185-92 [Journal] [PubMed]
Nitta J, Furukawa T, Marumo F, Sawanobori T, Hiraoka M (1994) Subcellular mechanism for Ca(2+)-dependent enhancement of delayed rectifier K+ current in isolated membrane patches of guinea pig ventricular myocytes. Circ Res 74:96-104 [PubMed]
Qin D, Zhang ZH, Caref EB, Boutjdir M, Jain P, el-Sherif N (1996) Cellular and ionic basis of arrhythmias in postinfarction remodeled ventricular myocardium. Circ Res 79:461-73 [PubMed]
Restivo M, Caref EB, Choi BR, Salama G (1997) Bradycardia dependent non-uniform repolarization gradients in a guinea-pig model of long QT syndrome Circulation 96:554
Roden DM (1993) Early after-depolarizations and torsade de pointes: implications for the control of cardiac arrhythmias by prolonging repolarization. Eur Heart J 14 Suppl H:56-61 [PubMed]
Roden DM, Thompson KA, Hoffman BF, Woosley RL (1986) Clinical features and basic mechanisms of quinidine-induced arrhythmias. J Am Coll Cardiol 8:73A-78A [PubMed]
Romey G, Attali B, Chouabe C, Abitbol I, Guillemare E, Barhanin J, Lazdunski M (1997) Molecular mechanism and functional significance of the MinK control of the KvLQT1 channel activity. J Biol Chem 272:16713-6 [PubMed]
Shimizu W, Antzelevitch C (1997) Sodium channel block with mexiletine is effective in reducing dispersion of repolarization and preventing torsade des pointes in LQT2 and LQT3 models of the long-QT syndrome. Circulation 96:2038-47 [PubMed]
Shimizu W, Kurita T, Matsuo K, Suyama K, Aihara N, Kamakura S, Towbin JA, Shimomura K (1998) Improvement of repolarization abnormalities by a K+ channel opener in the LQT1 form of congenital long-QT syndrome. Circulation 97:1581-8 [PubMed]
Shimizu W, Ohe T, Kurita T, Kawade M, Arakaki Y, Aihara N, Kamakura S, Kamiya T, Shimomura K (1995) Effects of verapamil and propranolol on early afterdepolarizations and ventricular arrhythmias induced by epinephrine in congenital long QT syndrome. J Am Coll Cardiol 26:1299-309 [Journal] [PubMed]
Sicouri S, Antzelevitch C (1991) A subpopulation of cells with unique electrophysiological properties in the deep subepicardium of the canine ventricle. The M cell. Circ Res 68:1729-41 [PubMed]
Sicouri S, Quist M, Antzelevitch C (1996) Evidence for the presence of M cells in the guinea pig ventricle. J Cardiovasc Electrophysiol 7:503-11 [PubMed]
Surawicz B (1989) Electrophysiologic substrate of torsade de pointes: dispersion of repolarization or early afterdepolarizations? J Am Coll Cardiol 14:172-84 [PubMed]
Verduyn SC, Vos MA, van der Zande J, van der Hulst FF, Wellens HJ (1997) Role of interventricular dispersion of repolarization in acquired torsade-de-pointes arrhythmias: reversal by magnesium. Cardiovasc Res 34:453-63 [PubMed]
Vincent GM (1998) The molecular genetics of the long QT syndrome: genes causing fainting and sudden death. Annu Rev Med 49:263-74 [Journal] [PubMed]
Viswanathan PC, Rudy Y (1997) Differential sensitivity of ventricular cell types to class III antiarrhythmic agents Biophys J 72:48
Viswanathan PC, Shaw RM, Rudy Y (1999) Effects of IKr and IKs heterogeneity on action potential duration and its rate dependence: a simulation study. Circulation 99:2466-74 [PubMed]
   Ventricular cell model (Guinea-pig-type) (Luo, Rudy 1991, +11 other papers!) (C++) [Model]
Vos MA, Verduyn SC, Gorgels AP, Lipcsei GC, Wellens HJ (1995) Reproducible induction of early afterdepolarizations and torsade de pointes arrhythmias by d-sotalol and pacing in dogs with chronic atrioventricular block. Circulation 91:864-72 [PubMed]
Wang DW, Yazawa K, Makita N, George AL, Bennett PB (1997) Pharmacological targeting of long QT mutant sodium channels. J Clin Invest 99:1714-20 [Journal] [PubMed]
Wang Q, Chen Q, Towbin JA (1998) Genetics, molecular mechanisms and management of long QT syndrome. Ann Med 30:58-65 [PubMed]
Zabel M, Hohnloser SH, Behrens S, Li YG, Woosley RL, Franz MR (1997) Electrophysiologic features of torsades de pointes: insights from a new isolated rabbit heart model. J Cardiovasc Electrophysiol 8:1148-58 [PubMed]
Zeng J (1997) A dynamic model of a cardiac ventricular action potential Thesis
Zeng J, Laurita KR, Rosenbaum DS, Rudy Y (1995) Two components of the delayed rectifier K+ current in ventricular myocytes of the guinea pig type. Theoretical formulation and their role in repolarization. Circ Res 77:140-52 [PubMed]
   Ventricular cell model (Guinea-pig-type) (Luo, Rudy 1991, +11 other papers!) (C++) [Model]
Zeng J, Rudy Y (1995) Early afterdepolarizations in cardiac myocytes: mechanism and rate dependence. Biophys J 68:949-64 [Journal] [PubMed]
   Ventricular cell model (Guinea-pig-type) (Luo, Rudy 1991, +11 other papers!) (C++) [Model]
Zhou JT, Zheng LR, Liu WY (1992) Role of early afterdepolarization in familial long QTU syndrome and torsade de pointes. Pacing Clin Electrophysiol 15:2164-8 [PubMed]
Clancy CE, Rudy Y (2001) Cellular consequences of HERG mutations in the long QT syndrome: precursors to sudden cardiac death. Cardiovasc Res 50:301-13 [PubMed]
   Consequences of HERG mutations in the long QT syndrome (Clancy, Rudy 2001) [Model]
Clancy CE, Rudy Y (2002) Na(+) channel mutation that causes both Brugada and long-QT syndrome phenotypes: a simulation study of mechanism. Circulation 105:1208-13 [PubMed]
   Markovian model for cardiac sodium channel (Clancy, Rudy 2002) [Model]
Viswanathan PC, Rudy Y (2000) Cellular arrhythmogenic effects of congenital and acquired long-QT syndrome in the heterogeneous myocardium. Circulation 101:1192-8 [PubMed]
   Ventricular cell model (Guinea-pig-type) (Luo, Rudy 1991, +11 other papers!) (C++) [Model]
(54 refs)