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Faber GM, Rudy Y (2000) Action potential and contractility changes in [Na(+)](i) overloaded cardiac myocytes: a simulation study. Biophys J 78:2392-404 [PubMed]

   Ventricular cell model (Guinea-pig-type) (Luo, Rudy 1991, +11 other papers!) (C++)

References and models cited by this paper

References and models that cite this paper

Bennett PB, Yazawa K, Makita N, George AL (1995) Molecular mechanism for an inherited cardiac arrhythmia. Nature 376:683-5 [Journal] [PubMed]
Berlin JR, Cannell MB, Lederer WJ (1987) Regulation of twitch tension in sheep cardiac Purkinje fibers during calcium overload. Am J Physiol 253:H1540-7 [Journal] [PubMed]
Bers DM, Christensen DM, Nguyen TX (1988) Can Ca entry via Na-Ca exchange directly activate cardiac muscle contraction? J Mol Cell Cardiol 20:405-14 [PubMed]
Brill DM, Wasserstrom JA (1986) Intracellular sodium and the positive inotropic effect of veratridine and cardiac glycoside in sheep Purkinje fibers. Circ Res 58:109-19 [PubMed]
Carl SL, Felix K, Caswell AH, Brandt NR, Ball WJ, Vaghy PL, Meissner G, Ferguson DG (1995) Immunolocalization of sarcolemmal dihydropyridine receptor and sarcoplasmic reticular triadin and ryanodine receptor in rabbit ventricle and atrium. J Cell Biol 129:673-82 [PubMed]
Carmeliet E (1992) A fuzzy subsarcolemmal space for intracellular Na+ in cardiac cells? Cardiovasc Res 26:433-42 [PubMed]
Chandra R, Starmer CF, Grant AO (1998) Multiple effects of KPQ deletion mutation on gating of human cardiac Na+ channels expressed in mammalian cells. Am J Physiol 274:H1643-54 [Journal] [PubMed]
Clancy CE, Rudy Y (1999) Linking a genetic defect to its cellular phenotype in a cardiac arrhythmia. Nature 400:566-9 [Journal] [PubMed]
   Ventricular cell model (Guinea-pig-type) (Luo, Rudy 1991, +11 other papers!) (C++) [Model]
Cohen CJ, Fozzard HA, Sheu SS (1982) Increase in intracellular sodium ion activity during stimulation in mammalian cardiac muscle. Circ Res 50:651-62 [PubMed]
Cranefield PF, Aronson RS (1988) Cardiac Arrhythmias: The Role of Triggered Activity and Other Mechanisms
Dumaine R, Wang Q, Keating MT, Hartmann HA, Schwartz PJ, Brown AM, Kirsch GE (1996) Multiple mechanisms of Na+ channel--linked long-QT syndrome. Circ Res 78:916-24 [PubMed]
Ellis D (1977) The effects of external cations and ouabain on the intracellular sodium activity of sheep heart Purkinje fibres. J Physiol 273:211-40 [PubMed]
Ferrier GR, Howlett SE (1995) Contractions in guinea-pig ventricular myocytes triggered by a calcium-release mechanism separate from Na+ and L-currents. J Physiol 484 ( Pt 1):107-22 [PubMed]
Frank JS, Mottino G, Reid D, Molday RS, Philipson KD (1992) Distribution of the Na(+)-Ca2+ exchange protein in mammalian cardiac myocytes: an immunofluorescence and immunocolloidal gold-labeling study. J Cell Biol 117:337-45 [PubMed]
Gao T, Puri TS, Gerhardstein BL, Chien AJ, Green RD, Hosey MM (1997) Identification and subcellular localization of the subunits of L-type calcium channels and adenylyl cyclase in cardiac myocytes. J Biol Chem 272:19401-7 [PubMed]
Haigney MC, Lakatta EG, Stern MD, Silverman HS (1994) Sodium channel blockade reduces hypoxic sodium loading and sodium-dependent calcium loading. Circulation 90:391-9 [PubMed]
Harrison SM, McCall E, Boyett MR (1992) The relationship between contraction and intracellular sodium in rat and guinea-pig ventricular myocytes. J Physiol 449:517-50 [PubMed]
Irisawa H, Sato R (1986) Intra- and extracellular actions of proton on the calcium current of isolated guinea pig ventricular cells. Circ Res 59:348-55 [PubMed]
Kameyama M, Kakei M, Sato R, Shibasaki T, Matsuda H, Irisawa H (1984) Intracellular Na+ activates a K+ channel in mammalian cardiac cells. Nature 309:354-6 [PubMed]
Karmazyn M (1996) The sodium-hydrogen exchange system in the heart: its role in ischemic and reperfusion injury and therapeutic implications. Can J Cardiol 12:1074-82 [PubMed]
Kieval RS, Bloch RJ, Lindenmayer GE, Ambesi A, Lederer WJ (1992) Immunofluorescence localization of the Na-Ca exchanger in heart cells. Am J Physiol 263:C545-50 [Journal] [PubMed]
Kohomoto O, Levi AJ, Bridge JH (1994) Relation between reverse sodium-calcium exchange and sarcoplasmic reticulum calcium release in guinea pig ventricular cells. Circ Res 74:550-4 [PubMed]
Leblanc N, Hume JR (1990) Sodium current-induced release of calcium from cardiac sarcoplasmic reticulum. Science 248:372-6 [PubMed]
Levesque PC, Leblanc N, Hume JR (1994) Release of calcium from guinea pig cardiac sarcoplasmic reticulum induced by sodium-calcium exchange. Cardiovasc Res 28:370-8 [PubMed]
Levi AJ (1991) The effect of strophanthidin on action potential, calcium current and contraction in isolated guinea-pig ventricular myocytes. J Physiol 443:1-23 [PubMed]
Levi AJ (1993) A role for sodium/calcium exchange in the action potential shortening caused by strophanthidin in guinea pig ventricular myocytes. Cardiovasc Res 27:471-81 [PubMed]
Levi AJ, Dalton GR, Hancox JC, Mitcheson JS, Issberner J, Bates JA, Evans SJ, Howarth FC, Hobai IA, Jones JV (1997) Role of intracellular sodium overload in the genesis of cardiac arrhythmias. J Cardiovasc Electrophysiol 8:700-21 [PubMed]
Levi AJ, Spitzer KW, Kohmoto O, Bridge JH (1994) Depolarization-induced Ca entry via Na-Ca exchange triggers SR release in guinea pig cardiac myocytes. Am J Physiol 266:H1422-33 [Journal] [PubMed]
Litwin S, Kohmoto O, Levi AJ, Spitzer KW, Bridge JH (1996) Evidence that reverse Na-Ca exchange can trigger SR calcium release. Ann N Y Acad Sci 779:451-63 [PubMed]
Litwin SE, Bridge JH (1997) Enhanced Na(+)-Ca2+ exchange in the infarcted heart. Implications for excitation-contraction coupling. Circ Res 81:1083-93 [PubMed]
Litwin SE, Li J, Bridge JH (1998) Na-Ca exchange and the trigger for sarcoplasmic reticulum Ca release: studies in adult rabbit ventricular myocytes. Biophys J 75:359-71 [Journal] [PubMed]
Lu HR, De Clerck F (1993) R 56 865, a Na+/Ca(2+)-overload inhibitor, protects against aconitine-induced cardiac arrhythmias in vivo. J Cardiovasc Pharmacol 22:120-5 [PubMed]
Luk HN, Carmeliet E (1990) Na(+)-activated K+ current in cardiac cells: rectification, open probability, block and role in digitalis toxicity. Pflugers Arch 416:766-8 [PubMed]
Luo CH, Rudy Y (1994) A dynamic model of the cardiac ventricular action potential. II. Afterdepolarizations, triggered activity, and potentiation. Circ Res 74:1097-113 [PubMed]
   Ventricular cell model (Luo Rudy dynamic model) (Luo Rudy 1994) used in (Wang et al 2006) (XPP) [Model]
   Ventricular cell model (Guinea-pig-type) (Luo, Rudy 1991, +11 other papers!) (C++) [Model]
Luo CH, Rudy Y (1994) A dynamic model of the cardiac ventricular action potential. I. Simulations of ionic currents and concentration changes. Circ Res 74:1071-96 [PubMed]
   Ventricular cell model (Guinea-pig-type) (Luo, Rudy 1991, +11 other papers!) (C++) [Model]
Matsuoka S, Hilgemann DW (1992) Steady-state and dynamic properties of cardiac sodium-calcium exchange. Ion and voltage dependencies of the transport cycle. J Gen Physiol 100:963-1001 [PubMed]
Nagatomo T, Fan Z, Ye B, Tonkovich GS, January CT, Kyle JW, Makielski JC (1998) Temperature dependence of early and late currents in human cardiac wild-type and long Q-T DeltaKPQ Na+ channels. Am J Physiol 275:H2016-24 [Journal] [PubMed]
Nakao M, Gadsby DC (1989) [Na] and [K] dependence of the Na/K pump current-voltage relationship in guinea pig ventricular myocytes. J Gen Physiol 94:539-65 [PubMed]
Nuss HB, Houser SR (1992) Sodium-calcium exchange-mediated contractions in feline ventricular myocytes. Am J Physiol 263:H1161-9 [Journal] [PubMed]
Radford NB, Makos JD, Ramasamy R, Sherry AD, Malloy CR (1998) Dissociation of intracellular sodium from contractile state in guinea-pig hearts treated with ouabain. J Mol Cell Cardiol 30:639-47 [Journal] [PubMed]
Ravens U, Himmel HM (1999) Drugs preventing Na+ and Ca2+ overload. Pharmacol Res 39:167-74 [Journal] [PubMed]
Sanguinetti MC (1990) Na+-activated and ATP-sensitive K+ channels in the heart Potassium Channels: Basic Function and Therapeutic Aspects, Colatsky TJ, ed. pp.85
Shaw RM, Rudy Y (1997) Electrophysiologic effects of acute myocardial ischemia: a theoretical study of altered cell excitability and action potential duration. Cardiovasc Res 35:256-72 [PubMed]
   Ventricular cell model (Guinea-pig-type) (Luo, Rudy 1991, +11 other papers!) (C++) [Model]
Sipido KR, Maes M, Van de Werf F (1997) Low efficiency of Ca2+ entry through the Na(+)-Ca2+ exchanger as trigger for Ca2+ release from the sarcoplasmic reticulum. A comparison between L-type Ca2+ current and reverse-mode Na(+)-Ca2+ exchange. Circ Res 81:1034-44 [PubMed]
Smith TW, Antman EM, Friedman PL, Blatt CM, Marsh JD (1984) Digitalis glycosides: mechanisms and manifestations of toxicity. Part I. Prog Cardiovasc Dis 26:413-58 [PubMed]
Tani M, Neely JR (1990) Na+ accumulation increases Ca2+ overload and impairs function in anoxic rat heart. J Mol Cell Cardiol 22:57-72 [PubMed]
van Echteld CJ, Kirkels JH, Eijgelshoven MH, van der Meer P, Ruigrok TJ (1991) Intracellular sodium during ischemia and calcium-free perfusion: a 23Na NMR study. J Mol Cell Cardiol 23:297-307 [PubMed]
Varghese A, Sell GR (1997) A conservation principle and its effect on the formulation of Na-Ca exchanger current in cardiac cells. J Theor Biol 189:33-40 [Journal] [PubMed]
Veldkamp MW, Vereecke J, Carmeliet E (1994) Effects of intracellular sodium and hydrogen ion on the sodium activated potassium channel in isolated patches from guinea pig ventricular myocytes. Cardiovasc Res 28:1036-41 [PubMed]
Viswanathan PC, Shaw RM, Rudy Y (1999) Effects of IKr and IKs heterogeneity on action potential duration and its rate dependence: a simulation study. Circulation 99:2466-74 [PubMed]
   Ventricular cell model (Guinea-pig-type) (Luo, Rudy 1991, +11 other papers!) (C++) [Model]
Vornanen M, Shepherd N, Isenberg G (1994) Tension-voltage relations of single myocytes reflect Ca release triggered by Na/Ca exchange at 35 degrees C but not 23 degrees C. Am J Physiol 267:C623-32 [Journal] [PubMed]
Wang DY, Chae SW, Gong QY, Lee CO (1988) Role of aiNa in positive force-frequency staircase in guinea pig papillary muscle. Am J Physiol 255:C798-807 [Journal] [PubMed]
Wang Z, Kimitsuki T, Noma A (1991) Conductance properties of the Na(+)-activated K+ channel in guinea-pig ventricular cells. J Physiol 433:241-57 [PubMed]
Wasserstrom JA, Vites AM (1999) Activation of contraction in cat ventricular myocytes: effects of low Cd(2+) concentration and temperature. Am J Physiol 277:H488-98 [Journal] [PubMed]
Wendt-Gallitelli MF, Voigt T, Isenberg G (1993) Microheterogeneity of subsarcolemmal sodium gradients. Electron probe microanalysis in guinea-pig ventricular myocytes. J Physiol 472:33-44 [PubMed]
Wier WG, Hess P (1984) Excitation-contraction coupling in cardiac Purkinje fibers. Effects of cardiotonic steroids on the intracellular [Ca2+] transient, membrane potential, and contraction. J Gen Physiol 83:395-415
Zeng J, Laurita KR, Rosenbaum DS, Rudy Y (1995) Two components of the delayed rectifier K+ current in ventricular myocytes of the guinea pig type. Theoretical formulation and their role in repolarization. Circ Res 77:140-52 [PubMed]
   Ventricular cell model (Guinea-pig-type) (Luo, Rudy 1991, +11 other papers!) (C++) [Model]
Zeng J, Rudy Y (1995) Early afterdepolarizations in cardiac myocytes: mechanism and rate dependence. Biophys J 68:949-64 [Journal] [PubMed]
   Ventricular cell model (Guinea-pig-type) (Luo, Rudy 1991, +11 other papers!) (C++) [Model]
Clancy CE, Rudy Y (2001) Cellular consequences of HERG mutations in the long QT syndrome: precursors to sudden cardiac death. Cardiovasc Res 50:301-13 [PubMed]
   Consequences of HERG mutations in the long QT syndrome (Clancy, Rudy 2001) [Model]
Flaim SN, Giles WR, McCulloch AD (2006) Contributions of sustained INa and IKv43 to transmural heterogeneity of early repolarization and arrhythmogenesis in canine left ventricular myocytes. Am J Physiol Heart Circ Physiol 291:H2617-29 [Journal] [PubMed]
   INa and IKv4.3 heterogeneity in canine LV myocytes (Flaim et al 2006) [Model]
Greenstein JL, Hinch R, Winslow RL (2006) Mechanisms of excitation-contraction coupling in an integrative model of the cardiac ventricular myocyte. Biophys J 90:77-91 [Journal] [PubMed]
   Excitation-contraction coupling in an integrative heart cell model (Greenstein et al 2006) [Model]
Greenstein JL, Winslow RL (2002) An integrative model of the cardiac ventricular myocyte incorporating local control of Ca2+ release. Biophys J 83:2918-45 [Journal] [PubMed]
Gurkiewicz M, Korngreen A, Waxman SG, Lampert A (2011) Kinetic modeling of Nav1.7 provides insight into erythromelalgia-associated F1449V mutation. J Neurophysiol 105:1546-57 [Journal] [PubMed]
   HMM of Nav1.7 WT and F1449V (Gurkiewicz et al. 2011) [Model]
Hinch R, Greenstein JL, Tanskanen AJ, Xu L, Winslow RL (2004) A simplified local control model of calcium-induced calcium release in cardiac ventricular myocytes. Biophys J 87:3723-36 [Journal] [PubMed]
Iyer V, Mazhari R, Winslow RL (2004) A computational model of the human left-ventricular epicardial myocyte. Biophys J 87:1507-25 [Journal] [PubMed]
Severi S, Corsi C, Rocchetti M, Zaza A (2009) Mechanisms of beta-adrenergic modulation of I(Ks) in the guinea-pig ventricle: insights from experimental and model-based analysis. Biophys J 96:3862-72 [Journal] [PubMed]
   A model of beta-adrenergic modulation of IKs in the guinea-pig ventricle (Severi et al. 2009) [Model]
Sung RJ, Wu SN, Wu JS, Chang HD, Luo CH (2006) Electrophysiological mechanisms of ventricular arrhythmias in relation to Andersen-Tawil syndrome under conditions of reduced IK1: a simulation study. Am J Physiol Heart Circ Physiol 291:H2597-605 [Journal] [PubMed]
   Simulation study of Andersen-Tawil syndrome (Sung et al 2006) [Model]
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