Citation Relationships

Legends: Link to a Model Reference cited by multiple papers


Sack JT, Aldrich RW (2006) Binding of a Gating Modifier Toxin Induces Intersubunit Cooperativity Early in the Shaker K Channel's Activation Pathway J. Gen. Physiol. 128(1):119-132

References and models cited by this paper

References and models that cite this paper

Baker OS, Larsson HP, Mannuzzu LM, Isacoff EY (1998) Three transmembrane conformations and sequence-dependent displacement of the S4 domain in shaker K+ channel gating. Neuron 20:1283-94 [PubMed]
Cherny VV, DeCoursey TE (1999) pH-dependent inhibition of voltage-gated H(+) currents in rat alveolar epithelial cells by Zn(2+) and other divalent cations. J Gen Physiol 114:819-38 [PubMed]
Doyle DA, Morais Cabral J, Pfuetzner RA, Kuo A, Gulbis JM, Cohen SL, Chait BT, MacKinnon R (1998) The structure of the potassium channel: molecular basis of K+ conduction and selectivity. Science 280:69-77 [PubMed]
Elinder F, Arhem P (2003) Metal ion effects on ion channel gating. Q Rev Biophys 36:373-427 [PubMed]
Eriksson MA, Roux B (2002) Modeling the structure of agitoxin in complex with the Shaker K+ channel: a computational approach based on experimental distance restraints extracted from thermodynamic mutant cycles. Biophys J 83:2595-609
Garcia ML, Garcia-Calvo M, Hidalgo P, Lee A, MacKinnon R (1994) Purification and characterization of three inhibitors of voltage-dependent K+ channels from Leiurus quinquestriatus var. hebraeus venom. Biochemistry 33:6834-9 [PubMed]
Gilly WF, Armstrong CM (1982) Divalent cations and the activation kinetics of potassium channels in squid giant axons. J Gen Physiol 79:965-96 [PubMed]
Gross A, MacKinnon R (1996) Agitoxin footprinting the shaker potassium channel pore. Neuron 16:399-406 [PubMed]
Heginbotham L, MacKinnon R (1992) The aromatic binding site for tetraethylammonium ion on potassium channels. Neuron 8:483-91 [PubMed]
Hidalgo P, MacKinnon R (1995) Revealing the architecture of a K+ channel pore through mutant cycles with a peptide inhibitor. Science 268:307-10 [PubMed]
Horn R, Ding S, Gruber HJ (2000) Immobilizing the moving parts of voltage-gated ion channels. J Gen Physiol 116:461-76 [PubMed]
Horrigan FT, Cui J, Aldrich RW (1999) Allosteric voltage gating of potassium channels I. Mslo ionic currents in the absence of Ca(2+). J Gen Physiol 114:277-304 [PubMed]
   Allosteric gating of K channels (Horrigan et al 1999) [Model]
Hoshi T, Zagotta WN, Aldrich RW (1990) Biophysical and molecular mechanisms of Shaker potassium channel inactivation. Science 250:533-8 [PubMed]
Kanevsky M, Aldrich RW (1999) Determinants of voltage-dependent gating and open-state stability in the S5 segment of Shaker potassium channels. J Gen Physiol 114:215-42 [PubMed]
Kelley WP, Wolters AM, Sack JT, Jockusch RA, Jurchen JC, Williams ER, Sweedler JV, Gilly WF (2003) Characterization of a novel gastropod toxin (6-bromo-2-mercaptotryptamine) that inhibits shaker K channel activity. J Biol Chem 278:34934-42 [Journal] [PubMed]
Krezel AM, Kasibhatla C, Hidalgo P, MacKinnon R, Wagner G (1995) Solution structure of the potassium channel inhibitor agitoxin 2: caliper for probing channel geometry. Protein Sci 4:1478-89 [Journal] [PubMed]
Ledwell JL, Aldrich RW (1999) Mutations in the S4 region isolate the final voltage-dependent cooperative step in potassium channel activation. J Gen Physiol 113:389-414 [PubMed]
Lenaeus MJ, Vamvouka M, Focia PJ, Gross A (2005) Structural basis of TEA blockade in a model potassium channel. Nat Struct Mol Biol 12:454-9 [Journal] [PubMed]
Long SB, Campbell EB, Mackinnon R (2005) Crystal structure of a mammalian voltage-dependent Shaker family K+ channel. Science 309:897-903 [Journal] [PubMed]
Long SB, Campbell EB, Mackinnon R (2005) Voltage sensor of Kv1.2: structural basis of electromechanical coupling. Science 309:903-8 [Journal] [PubMed]
López-Barneo J, Hoshi T, Heinemann SH, Aldrich RW (1993) Effects of external cations and mutations in the pore region on C-type inactivation of Shaker potassium channels. Receptors Channels 1:61-71 [PubMed]
Lu Z, Klem AM, Ramu Y (2001) Ion conduction pore is conserved among potassium channels. Nature 413:809-13 [Journal] [PubMed]
MacKinnon R (1991) Determination of the subunit stoichiometry of a voltage-activated potassium channel. Nature 350:232-5 [Journal] [PubMed]
MacKinnon R, Yellen G (1990) Mutations affecting TEA blockade and ion permeation in voltage-activated K+ channels. Science 250:276-9 [PubMed]
Mannuzzu LM, Isacoff EY (2000) Independence and cooperativity in rearrangements of a potassium channel voltage sensor revealed by single subunit fluorescence. J Gen Physiol 115:257-68 [PubMed]
Murata Y, Iwasaki H, Sasaki M, Inaba K, Okamura Y (2005) Phosphoinositide phosphatase activity coupled to an intrinsic voltage sensor. Nature 435:1239-43 [Journal] [PubMed]
Pathak M, Kurtz L, Tombola F, Isacoff E (2005) The cooperative voltage sensor motion that gates a potassium channel. J Gen Physiol 125:57-69 [Journal] [PubMed]
Ramsey IS, Moran MM, Chong JA, Clapham DE (2006) A voltage-gated proton-selective channel lacking the pore domain. Nature 440:1213-6 [Journal] [PubMed]
Ranganathan R, Lewis JH, MacKinnon R (1996) Spatial localization of the K+ channel selectivity filter by mutant cycle-based structure analysis. Neuron 16:131-9
Root MJ, MacKinnon R (1994) Two identical noninteracting sites in an ion channel revealed by proton transfer. Science 265:1852-6
Sack JT, Aldrich RW, Gilly WF (2004) A gastropod toxin selectively slows early transitions in the Shaker K channel's activation pathway. J Gen Physiol 123:685-96
Schoppa NE, Sigworth FJ (1998) Activation of shaker potassium channels. I. Characterization of voltage-dependent transitions. J Gen Physiol 111:271-94 [PubMed]
Schoppa NE, Sigworth FJ (1998) Activation of Shaker potassium channels. II. Kinetics of the V2 mutant channel. J Gen Physiol 111:295-311 [PubMed]
Schoppa NE, Sigworth FJ (1998) Activation of Shaker potassium channels. III. An activation gating model for wild-type and V2 mutant channels. J Gen Physiol 111:313-42 [PubMed]
Schumacher MA, Rivard AF, Bächinger HP, Adelman JP (2001) Structure of the gating domain of a Ca2+-activated K+ channel complexed with Ca2+/calmodulin. Nature 410:1120-4 [Journal] [PubMed]
Smith-Maxwell CJ, Ledwell JL, Aldrich RW (1998) Role of the S4 in cooperativity of voltage-dependent potassium channel activation. J Gen Physiol 111:399-420
Smith-Maxwell CJ, Ledwell JL, Aldrich RW (1998) Uncharged S4 residues and cooperativity in voltage-dependent potassium channel activation. J Gen Physiol 111:421-39 [PubMed]
Sokolova O, Kolmakova-Partensky L, Grigorieff N (2001) Three-dimensional structure of a voltage-gated potassium channel at 2.5 nm resolution. Structure 9:215-20 [PubMed]
Spires S, Begenisich T (1994) Modulation of potassium channel gating by external divalent cations. J Gen Physiol 104:675-92 [PubMed]
Sun Y, Olson R, Horning M, Armstrong N, Mayer M, Gouaux E (2002) Mechanism of glutamate receptor desensitization. Nature 417:245-53 [Journal] [PubMed]
Terlau H, Ludwig J, Steffan R, Pongs O, Stühmer W, Heinemann SH (1996) Extracellular Mg2+ regulates activation of rat eag potassium channel. Pflugers Arch 432:301-12 [PubMed]
Yellen G, Sodickson D, Chen TY, Jurman ME (1994) An engineered cysteine in the external mouth of a K+ channel allows inactivation to be modulated by metal binding. Biophys J 66:1068-75
Zagotta WN, Hoshi T, Aldrich RW (1994) Shaker potassium channel gating. III: Evaluation of kinetic models for activation. J Gen Physiol 103:321-62 [PubMed]
Zagotta WN, Hoshi T, Dittman J, Aldrich RW (1994) Shaker potassium channel gating. II: Transitions in the activation pathway. J Gen Physiol 103:279-319 [PubMed]
Zhang S, Kehl SJ, Fedida D (2001) Modulation of Kv1.5 potassium channel gating by extracellular zinc. Biophys J 81:125-36 [Journal] [PubMed]
(46 refs)