Thalamic transformation of pallidal input (Hadipour-Niktarash 2006)

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Accession:111870
"In Parkinson’s disease, neurons of the internal segment of the globus pallidus (GPi) display the low-frequency tremor-related oscillations. These oscillatory activities are transmitted to the thalamic relay nuclei. Computer models of the interacting thalamocortical (TC) and thalamic reticular (RE) neurons were used to explore how the TC-RE network processes the low-frequency oscillations of the GPi neurons. ..."
Reference:
1 . Hadipour-Niktarash A (2006) A computational model of how an interaction between the thalamocortical and thalamic reticular neurons transforms the low-frequency oscillations of the globus pallidus. J Comput Neurosci 20:299-320 [PubMed]
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Model Information (Click on a link to find other models with that property)
Model Type: Realistic Network; Neuron or other electrically excitable cell;
Brain Region(s)/Organism: Thalamus;
Cell Type(s): Thalamus geniculate nucleus/lateral principal neuron; Thalamus reticular nucleus cell;
Channel(s): I Na,t; I T low threshold; I K; I h; I Potassium;
Gap Junctions:
Receptor(s): GabaA; GabaB; AMPA;
Gene(s):
Transmitter(s):
Simulation Environment: MATLAB;
Model Concept(s): Parkinson's;
Implementer(s): Hadipour-Niktarash, Arash [arash.hadipour at gmail.com];
Search NeuronDB for information about:  Thalamus geniculate nucleus/lateral principal neuron; Thalamus reticular nucleus cell; GabaA; GabaB; AMPA; I Na,t; I T low threshold; I K; I h; I Potassium;
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Hadipour-Niktarash2006
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