A model of the femur-tibia control system in stick insects (Stein et al. 2008)

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Accession:118092
We studied the femur-tibia joint control system of the insect leg, and its switch between resistance reflex in posture control and "active reaction" in walking. The "active reaction" is basically a reversal of the resistance reflex. Both responses are elicited by the same sensory input and the same neuronal network (the femur-tibia network). The femur-tibia network was modeled by fitting the responses of model neurons to those obtained in animals. Each implemented neuron has a physiological counterpart. The strengths of 16 interneuronal pathways that integrate sensory input were then assigned three different values and varied independently, generating a database of more than 43 million network variants. The uploaded version contains the model that best represented the resistance reflex. Please see the README for more help. We demonstrate that the combinatorial code of interneuronal pathways determines motor output. A switch between different behaviors such as standing to walking can thus be achieved by altering the strengths of selected sensory integration pathways.
Reference:
1 . Stein W, Straub O, Ausborn J, Mader W, Wolf H (2008) Motor pattern selection by combinatorial code of interneuronal pathways. J Comput Neurosci 25:543-61 [PubMed]
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Model Information (Click on a link to find other models with that property)
Model Type: Realistic Network; Neuron or other electrically excitable cell; Synapse;
Brain Region(s)/Organism:
Cell Type(s): Stick insect nonspiking interneuron;
Channel(s):
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment: MadSim;
Model Concept(s): Detailed Neuronal Models; Invertebrate; Synaptic Integration;
Implementer(s): Mader, Wolfgang [wolfgang.mader at uni-ulm.de];
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madSim4.5
parameter
Rueckkopplungs-Objekte-Dateien
! bloss oinr.knl *
1 kanal.knl *
akt+inakt.knl
dialog texte de.txt
dialog texte en.txt
dialog texte en_alt.txt
Diffgleichungen_in_madSim.pdf
GB.channel *
GB.channel.description *
GB.channel.description.doc *
gb-parameter.txt *
gb-parameter.xls *
HH.channel *
HH.channel.description *
HH.channel.description.doc *
ioTabelle langsam.txt *
ioTabelle normal.txt *
ioTabelle test.txt
ioTabelle.txt *
izhikevich-typen.txt *
izhikevich-typen.txt.orig *
meldung texte de.txt
meldung texte en.txt
neuronParameter.xls
ONOFF.channel *
ONOFF.channel.description *
ONOFF.channel.description.doc *
ONOFF.NEU *
reizFuerServerBetrieb kurz.txt *
reizFuerServerBetrieb original.txt *
reizFuerServerBetrieb.txt *
Rueckkopplungs-Objekte.htm
STANDARD.CA *
STANDARD.GEN *
STANDARD.K *
STANDARD.NA *
STANDARD.NEU *
STANDARD.ON *
standardap 2000ms.TXT *
standardap 200ms.txt *
standardap original.TXT *
standardap.txt *
swim example.txt *
SWIM.channel *
SWIM.channel.description *
SWIM.channel.description.doc *
tooltip texte de.txt
tooltip texte en.txt
userDef SWIM kanal original.txt *
userDef SWIM kanal.knl
                            
[izhikevich standardtypen] ***********************
izhikevich typ 0 a=0.01
izhikevich typ 0 b=0.1
izhikevich typ 0 c=-65
izhikevich typ 0 d=8
izhikevich typ 0 tau=0.2
izhikevich typ 0 V=-70
izhikevich typ 0 U=-22
izhikevich typ 0 naE=40
izhikevich typ 0 bezeichnung=standard
izhikevich typ 1 a=0.02
izhikevich typ 1 b=0.2
izhikevich typ 1 c=-65
izhikevich typ 1 d=6
izhikevich typ 1 tau=0.2
izhikevich typ 1 V=-70
izhikevich typ 1 U=-20
izhikevich typ 1 naE=30
izhikevich typ 1 bezeichnung=tonic spiking
izhikevich typ 2 a=0.02
izhikevich typ 2 b=0.25
izhikevich typ 2 c=-65
izhikevich typ 2 d=6
izhikevich typ 2 tau=0.2
izhikevich typ 2 V=-70
izhikevich typ 2 U=-12
izhikevich typ 2 naE=30
izhikevich typ 2 bezeichnung=phasic spiking
izhikevich typ 3 a=0.02
izhikevich typ 3 b=0.2
izhikevich typ 3 c=-50
izhikevich typ 3 d=2
izhikevich typ 3 tau=0.2
izhikevich typ 3 V=-70
izhikevich typ 3 U=-20
izhikevich typ 3 naE=30
izhikevich typ 3 bezeichnung=tonic bursting
izhikevich typ 4 a=0.02
izhikevich typ 4 b=0.25
izhikevich typ 4 c=-55
izhikevich typ 4 d=0.05
izhikevich typ 4 tau=0.2
izhikevich typ 4 V=-70
izhikevich typ 4 U=-20
izhikevich typ 4 naE=30
izhikevich typ 4 bezeichnung=phasic bursting
izhikevich typ 5 a=0.02
izhikevich typ 5 b=0.2
izhikevich typ 5 c=-55
izhikevich typ 5 d=4
izhikevich typ 5 tau=0.2
izhikevich typ 5 V=-70
izhikevich typ 5 U=-20
izhikevich typ 5 naE=30
izhikevich typ 5 bezeichnung=mixed mode xxx
izhikevich typ 6 a=0.01
izhikevich typ 6 b=0.2
izhikevich typ 6 c=-65
izhikevich typ 6 d=8
izhikevich typ 6 tau=0.2
izhikevich typ 6 V=-70
izhikevich typ 6 U=-20
izhikevich typ 6 naE=30
izhikevich typ 6 bezeichnung=spike frequency adaptation
izhikevich typ 7 a=0.02
izhikevich typ 7 b=-0.1
izhikevich typ 7 c=-55
izhikevich typ 7 d=6
izhikevich typ 7 tau=0.2
izhikevich typ 7 V=-70
izhikevich typ 7 U=-20
izhikevich typ 7 naE=30
izhikevich typ 7 bezeichnung=Class 1
izhikevich typ 8 a=0.2
izhikevich typ 8 b=0.26
izhikevich typ 8 c=-65
izhikevich typ 8 d=0
izhikevich typ 8 tau=0.2
izhikevich typ 8 V=-70
izhikevich typ 8 U=-20
izhikevich typ 8 naE=30
izhikevich typ 8 bezeichnung=Class 2
izhikevich typ 9 a=0.02
izhikevich typ 9 b=0.2
izhikevich typ 9 c=-65
izhikevich typ 9 d=6
izhikevich typ 9 tau=0.2
izhikevich typ 9 V=-70
izhikevich typ 9 U=-20
izhikevich typ 9 naE=30
izhikevich typ 9 bezeichnung=spike latency
izhikevich typ 10 a=0.05
izhikevich typ 10 b=0.26
izhikevich typ 10 c=-60
izhikevich typ 10 d=0
izhikevich typ 10 tau=0.2
izhikevich typ 10 V=-70
izhikevich typ 10 U=-20
izhikevich typ 10 naE=30
izhikevich typ 10 bezeichnung=subthreshold oscillations
izhikevich typ 11 a=0.1
izhikevich typ 11 b=0.26
izhikevich typ 11 c=-60
izhikevich typ 11 d=-1
izhikevich typ 11 tau=0.2
izhikevich typ 11 V=-70
izhikevich typ 11 U=-20
izhikevich typ 11 naE=30
izhikevich typ 11 bezeichnung=resonator
izhikevich typ 12 a=0.02
izhikevich typ 12 b=-0.1
izhikevich typ 12 c=-55
izhikevich typ 12 d=6
izhikevich typ 12 tau=0.2
izhikevich typ 12 V=-70
izhikevich typ 12 U=-20
izhikevich typ 12 naE=30
izhikevich typ 12 bezeichnung=integrator
izhikevich typ 13 a=0.03
izhikevich typ 13 b=0.25
izhikevich typ 13 c=-60
izhikevich typ 13 d=4
izhikevich typ 13 tau=0.2
izhikevich typ 13 V=-70
izhikevich typ 13 U=-20
izhikevich typ 13 naE=30
izhikevich typ 13 bezeichnung=rebound spike
izhikevich typ 14 a=0.03
izhikevich typ 14 b=0.25
izhikevich typ 14 c=-52
izhikevich typ 14 d=0
izhikevich typ 14 tau=0.2
izhikevich typ 14 V=-70
izhikevich typ 14 U=-20
izhikevich typ 14 naE=30
izhikevich typ 14 bezeichnung=rebound burst
izhikevich typ 15 a=0.03
izhikevich typ 15 b=0.25
izhikevich typ 15 c=-60
izhikevich typ 15 d=4
izhikevich typ 15 tau=0.2
izhikevich typ 15 V=-70
izhikevich typ 15 U=-20
izhikevich typ 15 naE=30
izhikevich typ 15 bezeichnung=threshold variability
izhikevich typ 16 a=1
izhikevich typ 16 b=1.5
izhikevich typ 16 c=-60
izhikevich typ 16 d=0
izhikevich typ 16 tau=0.2
izhikevich typ 16 V=-70
izhikevich typ 16 U=-20
izhikevich typ 16 naE=30
izhikevich typ 16 bezeichnung=bistability
izhikevich typ 17 a=1
izhikevich typ 17 b=0.2
izhikevich typ 17 c=-60
izhikevich typ 17 d=-21
izhikevich typ 17 tau=0.2
izhikevich typ 17 V=-70
izhikevich typ 17 U=-20
izhikevich typ 17 naE=30
izhikevich typ 17 bezeichnung=DAP
izhikevich typ 18 a=0.02
izhikevich typ 18 b=1
izhikevich typ 18 c=-55
izhikevich typ 18 d=4
izhikevich typ 18 tau=0.2
izhikevich typ 18 V=-70
izhikevich typ 18 U=-20
izhikevich typ 18 naE=30
izhikevich typ 18 bezeichnung=accomodation
izhikevich typ 19 a=-0.02
izhikevich typ 19 b=-1
izhikevich typ 19 c=-60
izhikevich typ 19 d=8
izhikevich typ 19 tau=0.2
izhikevich typ 19 V=-70
izhikevich typ 19 U=-20
izhikevich typ 19 naE=30
izhikevich typ 19 bezeichnung=inhibition-induced spiking
izhikevich typ 20 a=-0.026
izhikevich typ 20 b=-1
izhikevich typ 20 c=-45
izhikevich typ 20 d=0
izhikevich typ 20 tau=0.2
izhikevich typ 20 V=-70
izhikevich typ 20 U=-20
izhikevich typ 20 naE=30
izhikevich typ 20 bezeichnung=inhibition-induced bursting
[ende izhikevich standardtypen] ***********************