Multisensory integration in the superior colliculus: a neural network model (Ursino et al. 2009)

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Accession:118261
" ... The model includes three distinct neural areas: two unimodal areas (auditory and visual) are devoted to a topological representation of external stimuli, and communicate via synaptic connections with a third downstream area (in the SC) responsible for multisensory integration. The present simulations show that the model, with a single set of parameters, can mimic various responses to different combinations of external stimuli including the inverse effectiveness, both in terms of multisensory enhancement and contrast, the existence of within- and cross-modality suppression between spatially disparate stimuli, a reduction of network settling time in response to cross-modal stimuli compared with individual stimuli. ..."
Reference:
1 . Ursino M, Cuppini C, Magosso E, Serino A, di Pellegrino G (2009) Multisensory integration in the superior colliculus: a neural network model. J Comput Neurosci 26:55-73 [PubMed]
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Model Information (Click on a link to find other models with that property)
Model Type: Realistic Network;
Brain Region(s)/Organism: Superior colliculus;
Cell Type(s):
Channel(s):
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment: MATLAB;
Model Concept(s): Activity Patterns; Vision; Audition;
Implementer(s):
%% CONTRAST
% Analysis of the multisensory contrast, defined as the difference
% between the activity of a SC neuron stimulated by two cross-modal stimuli
% coming from the same location in space and the sum of the two
% unisensory responses.

clear
% a constant visual input (Iv=12) paired with an acoustic stimulus 
% of different levels of intensity

load RANGE_DIN_kv7ka6_Ivisivo_12_LuDeboli_LmForti
load RANGE_DIN_Ivisivo_LuDeboli_LmForti
load RANGE_DIN_Iacustico_LuDeboli_LmForti

somma_Iv12Ia_LuDeboli_LmForti=xm_a_regime+xm_v_regime(13);
contrast_Iv12_LuDeboli_LmForti=xm_v12_regime-somma_Iv12Ia_LuDeboli_LmForti;

figure
plot(stimoli(13:length(stimoli)),contrast_Iv12_LuDeboli_LmForti(13:length(stimoli)),'b')
title('contrast - Visual Input fixed Iv=12')
xlabel('Acoustic input')
ylabel('CONTRAST')


clear
% a constant visual input (Iv=30) paired with an acoustic stimulus 
% of different levels of intensity

load RANGE_DIN_kv7ka6_Ivisivo_30_LuDeboli_LmForti
load RANGE_DIN_Ivisivo_LuDeboli_LmForti
load RANGE_DIN_Iacustico_LuDeboli_LmForti

somma_Iv30Ia_LuDeboli_LmForti=xm_a_regime+xm_v_regime(31);
contrast_Iv30_LuDeboli_LmForti=xm_v30_regime-somma_Iv30Ia_LuDeboli_LmForti;

figure
plot(stimoli(13:length(stimoli)),contrast_Iv30_LuDeboli_LmForti(13:length(stimoli)),'b')
title('contrast - Visual Input fixed Iv=30')
xlabel('Acoustic input')
ylabel('CONTRAST')