Self-organized olfactory pattern recognition (Kaplan & Lansner 2014)


Help downloading and running models
Accession:155157
" ... We present a large-scale network model with single and multi-compartmental Hodgkin–Huxley type model neurons representing olfactory receptor neurons (ORNs) in the epithelium, periglomerular cells, mitral/tufted cells and granule cells in the olfactory bulb (OB), and three types of cortical cells in the piriform cortex (PC). Odor patterns are calculated based on affinities between ORNs and odor stimuli derived from physico-chemical descriptors of behaviorally relevant real-world odorants. ... The PC was implemented as a modular attractor network with a recurrent connectivity that was likewise organized through Hebbian–Bayesian learning. We demonstrate the functionality of the model in a one-sniff-learning and recognition task on a set of 50 odorants. Furthermore, we study its robustness against noise on the receptor level and its ability to perform concentration invariant odor recognition. Moreover, we investigate the pattern completion capabilities of the system and rivalry dynamics for odor mixtures."
Reference:
1 . Kaplan BA, Lansner A (2014) A spiking neural network model of self-organized pattern recognition in the early mammalian olfactory system. Front Neural Circuits 8:5 [PubMed]
Citations  Citation Browser
Model Information (Click on a link to find other models with that property)
Model Type: Realistic Network;
Brain Region(s)/Organism: Olfactory cortex; Olfactory bulb;
Cell Type(s): Olfactory bulb main mitral cell; Olfactory receptor neuron; Olfactory cortex anterior pyramidal neuron; Olfactory bulb main interneuron periglomerular cell; Olfactory bulb main interneuron granule MC cell; Olfactory bulb main interneuron granule TC cell;
Channel(s): I Na,t; I L high threshold; I T low threshold; I A; I K; I M; I K,Ca; I Calcium;
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment: NEURON (web link to model);
Model Concept(s): Pattern Recognition; Activity Patterns; Attractor Neural Network;
Implementer(s):
Search NeuronDB for information about:  Olfactory bulb main mitral cell; Olfactory receptor neuron; Olfactory cortex anterior pyramidal neuron; Olfactory bulb main interneuron periglomerular cell; Olfactory bulb main interneuron granule MC cell; Olfactory bulb main interneuron granule TC cell; I Na,t; I L high threshold; I T low threshold; I A; I K; I M; I K,Ca; I Calcium;
(located via links below)