CA1 pyramidal cells, basket cells, ripples (Malerba et al 2016)

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Accession:188977
Model of CA1 pyramidal layer Ripple activity, triggered when receiving current input (to represent CA3 sharp-waves). Cells are Adaptive-Exponential Integrate and Fire neurons, receiving independent OU noise.
Reference:
1 . Malerba P, Krishnan GP, Fellous JM, Bazhenov M (2016) Hippocampal CA1 Ripples as Inhibitory Transients. PLoS Comput Biol 12:e1004880 [PubMed]
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Model Information (Click on a link to find other models with that property)
Model Type: Realistic Network;
Brain Region(s)/Organism:
Cell Type(s): Hippocampus CA1 pyramidal GLU cell; Hippocampus CA1 PV+ fast-firing interneuron;
Channel(s):
Gap Junctions:
Receptor(s): GabaA; AMPA;
Gene(s):
Transmitter(s):
Simulation Environment: MATLAB;
Model Concept(s): Oscillations; Sleep; Brain Rhythms;
Implementer(s):
Search NeuronDB for information about:  Hippocampus CA1 pyramidal GLU cell; GabaA; AMPA;
function [p] = defaultparamsCA1()

%params
p.CE = 200;
p.glE = 10;
p.ElE = -58;
p.aE = 2;
p.bE = 100;
p.slpE = 2;
p.twE = 120;
p.VtE = -50;
p.VrE = -46;

p.CI = 200;
p.glI = 10;
p.ElI = -70;
p.aI = 2;
p.bI = 10;
p.slpI = 2;
p.twI = 30;
p.VtI = -50;
p.VrI = -58;


p.gnoiseE = 80;
p.gnoiseI = 90;

% EtoE 
p.tauEr = 0.5;
p.tauEd = 3.5; 
% EtoB
p.tauEIr = 0.9;
p.tauEId = 3; %EPSP on inrn faster than on principal cells
% BtoB 
p.tauIr = 0.3;
p.tauId = 2;  % Bartos et al 2002
% BtoP is slower than BtoB
p.tauIEr = 0.3;
p.tauIEd = 3.5;

p.gmaxII = 3/(80/100);
p.gmaxEI = 2/(30/100);
p.gmaxIE = 5/(60/100);
p.gmaxEE = p.gmaxEI/10;%1on1 syn strength /percent synch efficacy

p.VrevE = 0; % mV reversal of excitatory syn
p.VrevI = -80;% mV rev of inhibitory syn

p.gvarEE = 0.01;
p.gvarII = 0.01;

p.gvarEI = 0.01;
p.gvarIE = 0.01;

p.DCstdI = 0.1;
p.DCstdE = 0.1;

p.Edc = 40;
p.jmpE = 210;
p.Idc = 180;
p.jmpI = 700;

p.seqsize = 10;
p.dcbias = 2;
return