This code implements a model for adult neurogenesis of granule cells in the olfactory system. The granule cells receive sensory input via the mitral cells and top-down input from a cortical area. That cortical area also receives olfactory input from the mitral cells as well as contextual input. This plasticity leads to a network structure consisting of bidirectional connections between bulbar and cortical odor representations. The top-down input enhances stimulus discrimination based on contextual input.
Adams W, Graham JN, Han X, Riecke H (2019) Top-down inputs drive neuronal network rewiring and context-enhanced sensory processing in olfaction. PLoS Comput Biol 15:e1006611 [PubMed]