Thalamic Reticular Network (Destexhe et al 1994)

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Accession:3670
Demo for simulating networks of thalamic reticular neurons (reproduces figures from Destexhe A et al 1994)
Reference:
1 . Destexhe A, Contreras D, Sejnowski TJ, Steriade M (1994) A model of spindle rhythmicity in the isolated thalamic reticular nucleus. J Neurophysiol 72:803-18 [PubMed]
Citations  Citation Browser
Model Information (Click on a link to find other models with that property)
Model Type: Realistic Network;
Brain Region(s)/Organism: Thalamus;
Cell Type(s): Thalamus reticular nucleus GABA cell;
Channel(s): I T low threshold; I K,Ca; I CAN;
Gap Junctions:
Receptor(s): GabaA; GabaB;
Gene(s):
Transmitter(s):
Simulation Environment: NEURON;
Model Concept(s): Activity Patterns; Temporal Pattern Generation; Oscillations; Tutorial/Teaching; Sleep; Calcium dynamics; Spindles;
Implementer(s): Destexhe, Alain [Destexhe at iaf.cnrs-gif.fr];
Search NeuronDB for information about:  Thalamus reticular nucleus GABA cell; GabaA; GabaB; I T low threshold; I K,Ca; I CAN;
//----------------------------------------------------------------------------
//  define a panel to run the different demos
//----------------------------------------------------------------------------

proc make_demopanel() {
	xpanel("Simulations of thalamic reticular network")
	xlabel("Simulations of thalamic reticular network")
	xbutton("Fig. 5a","restart(\"Fig5A\")")
	xbutton("Fig. 5b","restart(\"Fig5B\")")
        xbutton("Fig. 6a","restart(\"Fig6A\")")
        xbutton("Fig. 6b","restart(\"Fig6B\")")
	xbutton("Fig. 6c","restart(\"Fig6C\")")
	xbutton("Fig. 6d","restart(\"Fig6D\")")
        xbutton("Fig. 13a","restart(\"Fig13A\")")
	xbutton("Fig. 13b","restart(\"Fig13B\")")
	xpanel(5,100)
}


load_file("nrngui.hoc")

objref pwman
pwman = new PWManager()

proc rm_panel() {
	pwman.hide(1)
}

make_demopanel()

ismenu=0

//----------------------------------------------------------------------------
//  define a panel to run the different demos
//----------------------------------------------------------------------------

load_file("nrngui.hoc")

strdef tstr

objref El

electrodes_present=0	// after electrodes are created they must be
			// destroyed if simulation restarted

proc destroy_elec() {
	execute("objref stim, vc",El)
}

pwmcnt = PWManager[0].count  // the initial GUIs should not be dismissed
ismenu=0		// determines if electrode is defined


proc restart() { local i
	if (electrodes_present) {
		destroy_elec()
	}

	forall delete_section()

	for i=0, n_graph_lists-1 {
		graphList[i].remove_all()
	}
	flush_list.remove_all()
	fast_flush_list.remove_all()
	doNotify()
	for (i= PWManager[0].count-1; i >= pwmcnt; i -= 1) {
		PWManager[0].close(i)
		doNotify()
	}
	stoprun = 0
	cvode_active(0)
	
	sprint(tstr, "%s.hoc", $s1)
	load_file(1, tstr)
	ismenu=0	// used to reopen run control window
}