MicrocircuitDB: Dentate Gyrus Feed-forward inhibition (Ferrante et al. 2009)

Dentate Gyrus Feed-forward inhibition (Ferrante et al. 2009)

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Accession:124291

In this paper, the model was used to show how that FFI can change a steeply sigmoidal input-output (I/O) curve into a double-sigmoid typical of buffer systems.
Reference:
1 . Ferrante M, Migliore M, Ascoli GA (2009) Feed-forward inhibition as a buffer of the neuronal input-output relation. Proc Natl Acad Sci U S A 106:18004-9 [PubMed]

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Model Information (Click on a link to find other models with that property)

Model Type:	Realistic Network; Neuron or other electrically excitable cell;
Brain Region(s)/Organism:	Dentate gyrus;
Cell Type(s):	Dentate gyrus granule GLU cell; Dentate gyrus MOPP cell;
Channel(s):	I Na,t; I A; I K;
Gap Junctions:
Receptor(s):	GabaA; AMPA; NMDA;
Gene(s):
Transmitter(s):	Gaba; Glutamate;
Simulation Environment:	NEURON;
Model Concept(s):	Action Potential Initiation; Activity Patterns; Ion Channel Kinetics; Synchronization; Spatio-temporal Activity Patterns; Action Potentials; Noise Sensitivity;
Implementer(s):	Migliore, Michele [Michele.Migliore at Yale.edu]; Ferrante, Michele [mferr133 at bu.edu]; Ascoli, Giorgio A [ascoli at gmu.edu];

Search NeuronDB for information about: Dentate gyrus granule GLU cell; GabaA; AMPA; NMDA; I Na,t; I A; I K; Gaba; Glutamate;

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