Find models by
Find models for
Find models of
Balance of excitation and inhibition (Carvalho and Buonomano 2009)
Download zip file
Help downloading and running models
" ... Here, theoretical analyses reveal that excitatory synaptic strength controls the threshold of the neuronal input-output function, while inhibitory plasticity alters the threshold and gain. Experimentally, changes in the balance of excitation and inhibition in CA1 pyramidal neurons also altered their input-output function as predicted by the model. These results support the existence of two functional modes of plasticity that can be used to optimize information processing: threshold and gain plasticity."
Carvalho TP, Buonomano DV (2009) Differential effects of excitatory and inhibitory plasticity on synaptically driven neuronal input-output functions.
(Click on a link to find other models with that property)
Neuron or other electrically excitable cell;
Download the displayed file
ModelDB scripts have detected that binary file '/CarvalhoBuonomano/Neuron2009/X_SynSpace.lnk' is not displayable. You may download the file to examine if desired.
<- Select file from this column.
Load Model View