" ... the main rhythms displayed by the hippocampus, the gamma (30–90 Hz) and theta (4–12 Hz) rhythms. We concentrate on modeling
in vitro experiments, but with an eye toward possible in vivo implications. ...
We use simpler biophysical models; all cells have a single compartment only, and the
interneurons are restricted to two types: fast-spiking (FS) basket cells and oriens
lacunosum-moleculare (O-LM) cells.
... , we aim not so much at reproducing dynamics in great detail, but at clarifying the essential mechanisms underlying the production of the rhythms and their interactions (Kopell, 2005). ..."
Reference:
1 .
Tort AB, Rotstein HG, Dugladze T, Gloveli T, Kopell NJ (2007) On the formation of gamma-coherent cell assemblies by oriens lacunosum-moleculare interneurons in the hippocampus. Proc Natl Acad Sci U S A 104:13490-5 [PubMed]
2 .
Gloveli T, Dugladze T, Rotstein HG, Traub RD, Monyer H, Heinemann U, Whittington MA, Kopell NJ (2005) Orthogonal arrangement of rhythm-generating microcircuits in the hippocampus. Proc Natl Acad Sci U S A 102:13295-300 [PubMed]
3 .
Kopell N, Borgers C, Pervouchine D, Malerba P, Tort ABL (2010) Gamma and theta rhythms in biophysical models of hippocampal circuits Hippocampal Microcircuits: A Computational Modeller`s Resource Book. Ch. 15., Cutsuridis V, Graham BF, Cobb S, Vida I, ed.
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