Cardiac action potentials and pacemaker activity of sinoatrial node (DiFrancesco & Noble 1985)

 Download zip file   Auto-launch 
Help downloading and running models
Accession:144520
"Equations have been developed to describe cardiac action potentials and pacemaker activity. The model takes account of extensive developments in experimental work ..."
Reference:
1 . DiFrancesco D, Noble D (1985) A model of cardiac electrical activity incorporating ionic pumps and concentration changes. Philos Trans R Soc Lond B Biol Sci 307:353-98 [PubMed]
Citations  Citation Browser
Model Information (Click on a link to find other models with that property)
Model Type: Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Cell Type(s): Cardiac atrial cell; Cardiac ventricular cell;
Channel(s): I Na,t; I K; I h; I Calcium; I Potassium; Na/Ca exchanger; Na/K pump;
Gap Junctions:
Receptor(s):
Gene(s): HCN4;
Transmitter(s):
Simulation Environment: NEURON;
Model Concept(s): Action Potentials;
Implementer(s): Gannier, Francois [francois.gannier at univ-tours.fr];
Search NeuronDB for information about:  I Na,t; I K; I h; I Calcium; I Potassium; Na/Ca exchanger; Na/K pump;
UNITS {
	(mN) = (millinewton)
	(um) = (micron)
	(mV) = (millivolt)
	(L)  = (liter)
	(nL) = (nanoliter)
	(pL) = (picoliter)
	(nM) = (nano/liter)
	(mM) = (milli/liter)
	(uM) = (micro/liter)
	(mA) = (milliamp)
	(uA) = (microamp)
	(nA) = (nanoamp)
	(pA) = (picoamp)
	(S) = (siemens)
	(uS) = (microsiemens)
	(mS) = (millisiemens)
	(nS) = (nanosiemens)
	(pS) = (picosiemens)
	(uF) = (microfarad)
	(nF) = (nanofarad)
	(mF) = (millifarad)
	(pF) = (picofarad)
	(F) = (farad)
	F = (faraday) (coulombs)
	R = (k-mole)	(joule/degC)	
}