Cardiac action potentials and pacemaker activity of sinoatrial node (DiFrancesco & Noble 1985)

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"Equations have been developed to describe cardiac action potentials and pacemaker activity. The model takes account of extensive developments in experimental work ..."
1 . DiFrancesco D, Noble D (1985) A model of cardiac electrical activity incorporating ionic pumps and concentration changes. Philos Trans R Soc Lond B Biol Sci 307:353-98 [PubMed]
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Model Information (Click on a link to find other models with that property)
Model Type: Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Cell Type(s): Cardiac atrial cell; Cardiac ventricular cell;
Channel(s): I Na,t; I K; I h; I Calcium; I Potassium; Na/Ca exchanger; Na/K pump;
Gap Junctions:
Gene(s): HCN4;
Simulation Environment: NEURON;
Model Concept(s): Action Potentials;
Implementer(s): Gannier, Francois [francois.gannier at];
Search NeuronDB for information about:  I Na,t; I K; I h; I Calcium; I Potassium; Na/Ca exchanger; Na/K pump;
	celsius = 37
	diam=0.05  L=2 nseg = 1
	insert capacitance { cm = 1.2}   // 0.0756µF
	v_init = -87
	RPot = v_init

proc concentration_init() {
	cao0_ca_ion = 1.8
	cai0_ca_ion = 5e-5

	cri0_cr_ion = 1
	cui0_cu_ion = 2

	ki0_k_ion = 140
	ko0_k_ion = 4

	nai0_na_ion = 8
	nao0_na_ion = 140