Human sleep/wake cycle (Rempe et al. 2010)

 Download zip file 
Help downloading and running models
Accession:147748
This model simulates sleep in the human brain and is consistent with both the flip/flop concept and the two-process model of sleep regulation. The model also gives a possible mechanism for the changes in sleep timing seen in narcolepsy.
Reference:
1 . Rempe MJ, Best J, Terman D (2010) A mathematical model of the sleep/wake cycle. J Math Biol 60:615-44 [PubMed]
Citations  Citation Browser
Model Information (Click on a link to find other models with that property)
Model Type: Realistic Network;
Brain Region(s)/Organism:
Cell Type(s):
Channel(s):
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s): Gaba;
Simulation Environment: XPPAUT;
Model Concept(s): Sleep;
Implementer(s): Rempe, Michael [mrempe at whitworth.edu];
Search NeuronDB for information about:  Gaba;
 
/
flipflop
readme.html
flipflop.ode
screenshot.png
                            
File not selected

<- Select file from this column.