Dentate gyrus granule cell: subthreshold signal processing (Schmidt-Hieber et al. 2007)

 Download zip file   Auto-launch 
Help downloading and running models
Accession:95960
Detailed compartmental cable models of 8 hippocampal granule cells of adult mice were obtained from dual patch-clamp whole-cell recordings and subsequent 3D reconstructions. This code allows to reproduce figures 6-8 from the paper.
Reference:
1 . Schmidt-Hieber C, Jonas P, Bischofberger J (2007) Subthreshold dendritic signal processing and coincidence detection in dentate gyrus granule cells. J Neurosci 27:8430-41 [PubMed]
Citations  Citation Browser
Model Information (Click on a link to find other models with that property)
Model Type: Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Cell Type(s): Dentate gyrus granule GLU cell;
Channel(s):
Gap Junctions:
Receptor(s): AMPA; Glutamate;
Gene(s):
Transmitter(s): Glutamate;
Simulation Environment: NEURON;
Model Concept(s): Parameter Fitting; Influence of Dendritic Geometry; Synaptic Integration;
Implementer(s): Schmidt-Hieber, Christoph [c.schmidt-hieber at ucl.ac.uk];
Search NeuronDB for information about:  Dentate gyrus granule GLU cell; AMPA; Glutamate; Glutamate;
COMMENT
	Introduces a spine area scale factor as a range variable.
	This doesn't do magic: it will NOT automatically correct
	for spines. You will still have to multiply surface-dependent
	variables (capacitance, conductances) with scale_spines.
	Copied from 
	http://www.northwestern.edu/neurobiology/faculty/spruston/sk_models/JP_2005/Attenuation.zip
	last retrieved 02-2007
	Golding NL, Mickus TJ, Katz Y, Kath WL, Spruston N (2005)
	Factors mediating powerful voltage attenuation along CA1 
	pyramidal neuron dendrites. J Physiol (Lond) 568:69-82.

	2007-05-15, CSH, University of Freiburg 
ENDCOMMENT

NEURON {
	SUFFIX spines
	RANGE scale, count
}

PARAMETER {
	scale = 1
	count = 0
}