MicrocircuitDB: CA1 pyramidal neuron: calculation of MRI signals (Cassara et al. 2008)

CA1 pyramidal neuron: calculation of MRI signals (Cassara et al. 2008)

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Accession:106551

NEURON mod files from the paper: Cassarà AM, Hagberg GE, Bianciardi M, Migliore M, Maraviglia B. Realistic simulations of neuronal activity: A contribution to the debate on direct detection of neuronal currents by MRI. Neuroimage. 39:87-106 (2008). In this paper, we use a detailed calculation of the magnetic field produced by the neuronal currents propagating over a hippocampal CA1 pyramidal neuron placed inside a cubic MR voxel of length 1.2 mm to estimate the Magnetic Resonance signal.
Reference:
1 . Cassarà AM, Hagberg GE, Bianciardi M, Migliore M, Maraviglia B (2008) Realistic simulations of neuronal activity: a contribution to the debate on direct detection of neuronal currents by MRI. Neuroimage 39:87-106 [PubMed]
2 . Cassarà AM, Maraviglia B (2008) Microscopic investigation of the resonant mechanism for the implementation of nc-MRI at ultra-low field MRI. Neuroimage 41:1228-41 [PubMed]

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Model Type:	Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Cell Type(s):	Hippocampus CA1 pyramidal GLU cell;
Channel(s):	I Na,t; I A; I K; I h;
Gap Junctions:
Receptor(s):	AMPA;
Gene(s):
Transmitter(s):	Glutamate;
Simulation Environment:	NEURON;
Model Concept(s):	Active Dendrites; Detailed Neuronal Models; Extracellular Fields;
Implementer(s):