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STDP depends on dendritic synapse location (Letzkus et al. 2006)
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Accession:
108459
This model was published in Letzkus, Kampa & Stuart (2006) J Neurosci 26(41):10420-9. The simulation creates several plots showing voltage and NMDA current and conductance changes at different apical dendritic locations in layer 5 pyramidal neurons during STDP induction protocols. Created by B. Kampa (2006).
Reference:
1 .
Letzkus JJ, Kampa BM, Stuart GJ (2006) Learning rules for spike timing-dependent plasticity depend on dendritic synapse location.
J Neurosci
26
:10420-9
[
PubMed
]
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Model Information
(Click on a link to find other models with that property)
Model Type:
Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Cell Type(s):
Neocortex L5/6 pyramidal GLU cell;
Channel(s):
I L high threshold;
I T low threshold;
I A;
I M;
I K,Ca;
I Sodium;
I Calcium;
I Potassium;
Gap Junctions:
Receptor(s):
NMDA;
Gene(s):
Transmitter(s):
Glutamate;
Simulation Environment:
NEURON;
Model Concept(s):
Dendritic Action Potentials;
Bursting;
Active Dendrites;
Synaptic Plasticity;
Long-term Synaptic Plasticity;
Action Potentials;
STDP;
Calcium dynamics;
Implementer(s):
Kampa, Bjorn M [Bjoern.Kampa at anu.edu.au];
Search NeuronDB
for information about:
Neocortex L5/6 pyramidal GLU cell
;
NMDA
;
I L high threshold
;
I T low threshold
;
I A
;
I M
;
I K,Ca
;
I Sodium
;
I Calcium
;
I Potassium
;
Glutamate
;
/
LetzkusEtAl2006
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