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CA3 pyramidal neuron (Safiulina et al. 2010)
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Accession:
126814
In this review some of the recent work carried out in our laboratory concerning the functional role of GABAergic signalling at immature mossy fibres (MF)-CA3 principal cell synapses has been highlighted. To compare the relative strength of CA3 pyramidal cell output in relation to their MF glutamatergic or GABAergic inputs in postnatal development, a realistic model was constructed taking into account the different biophysical properties of these synapses.
Reference:
1 .
Safiulina VF, Caiati MD, Sivakumaran S, Bisson G, Migliore M, Cherubini E (2010) Control of GABA Release at Mossy Fiber-CA3 Connections in the Developing Hippocampus.
Front Synaptic Neurosci
2
:1
[
PubMed
]
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Model Information
(Click on a link to find other models with that property)
Model Type:
Synapse;
Dendrite;
Brain Region(s)/Organism:
Hippocampus;
Cell Type(s):
Hippocampus CA3 pyramidal GLU cell;
Channel(s):
I Na,t;
I L high threshold;
I N;
I T low threshold;
I A;
I K;
I M;
I h;
I Calcium;
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Gaba;
Glutamate;
Simulation Environment:
NEURON;
Model Concept(s):
Action Potential Initiation;
Dendritic Action Potentials;
Bursting;
Temporal Pattern Generation;
Active Dendrites;
Detailed Neuronal Models;
Action Potentials;
Synaptic Integration;
Spike Frequency Adaptation;
Implementer(s):
Migliore, Michele [Michele.Migliore at Yale.edu];
Search NeuronDB
for information about:
Hippocampus CA3 pyramidal GLU cell
;
I Na,t
;
I L high threshold
;
I N
;
I T low threshold
;
I A
;
I K
;
I M
;
I h
;
I Calcium
;
Gaba
;
Glutamate
;
/
develop
readme.html
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Distinct current modules shape cellular dynamics in model neurons (Alturki et al 2016)
Distinct current modules shape cellular dynamics in model neurons (Alturki et al 2016)
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CA3 pyramidal neuron: firing properties (Hemond et al. 2008)
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Distinct current modules shape cellular dynamics in model neurons (Alturki et al 2016)
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gabaAt20.jpg
gabaAt40.jpg
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gluAt20.jpg
gluAt40.jpg
mosinit.hoc
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