MicrocircuitDB: A multi-compartment model for interneurons in the dLGN (Halnes et al. 2011)

A multi-compartment model for interneurons in the dLGN (Halnes et al. 2011)

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Accession:140249

This model for dLGN interneurons is presented in two parameterizations (P1 & P2), which were fitted to current-clamp data from two different interneurons (IN1 & IN2). The model qualitatively reproduces the responses in IN1 & IN2 under 8 different experimental condition, and quantitatively reproduces the I/O-relations (#spikes elicited as a function of injected current).
Reference:
1 . Halnes G, Augustinaite S, Heggelund P, Einevoll GT, Migliore M (2011) A multi-compartment model for interneurons in the dorsal lateral geniculate nucleus. PLoS Comput Biol 7:e1002160 [PubMed]

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Model Information (Click on a link to find other models with that property)

Model Type:	Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Cell Type(s):	Thalamus lateral geniculate nucleus interneuron;
Channel(s):	I L high threshold; I T low threshold; I CAN; I Sodium; I Mixed; I Potassium; I_AHP;
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment:	NEURON;
Model Concept(s):	Activity Patterns; Active Dendrites; Detailed Neuronal Models; Rebound firing;
Implementer(s):	Halnes, Geir [geir.halnes at nmbu.no];