Find models by
Find models for
Find models of
Impact of dendritic atrophy on intrinsic and synaptic excitability (Narayanan & Chattarji, 2010)
Download zip file
Help downloading and running models
These simulations examined the atrophy induced changes in electrophysiological properties of CA3 pyramidal neurons. We found these neurons change from bursting to regular spiking as atrophy increases. Region-specific atrophy induced region-specific increases in synaptic excitability in a passive dendritic tree. All dendritic compartments of an atrophied neuron had greater synaptic excitability and a larger voltage transfer to the soma than the control neuron.
Narayanan R, Chattarji S (2010) Computational analysis of the impact of chronic stress on intrinsic and synaptic excitability in the hippocampus.
(Click on a link to find other models with that property)
Neuron or other electrically excitable cell;
Hippocampus CA3 pyramidal GLU cell;
I L high threshold;
I T low threshold;
Influence of Dendritic Geometry;
Detailed Neuronal Models;
Narayanan, Rishikesh [rishi at iisc.ac.in];
for information about:
Hippocampus CA3 pyramidal GLU cell
I L high threshold
I T low threshold
File not selected
<- Select file from this column.
Load Model Views