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Realistic Microcircuits
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Pyramidal neuron, fast, regular, and irregular spiking interneurons (Konstantoudaki et al 2014)
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Accession:
168310
This is a model network of prefrontal cortical microcircuit based primarily on rodent data. It includes 16 pyramidal model neurons, 2 fast spiking interneuron models, 1 regular spiking interneuron model and 1 irregular spiking interneuron model. The goal of the paper was to use this model network to determine the role of specific interneuron subtypes in persistent activity
Reference:
1 .
Konstantoudaki X, Papoutsi A, Chalkiadaki K, Poirazi P, Sidiropoulou K (2014) Modulatory effects of inhibition on persistent activity in a cortical microcircuit model.
Front Neural Circuits
8
:7
[
PubMed
]
Citations
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Model Information
(Click on a link to find other models with that property)
Model Type:
Realistic Network;
Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Cell Type(s):
Neocortex fast spiking (FS) interneuron;
Neocortex spiking regular (RS) neuron;
Neocortex spiking low threshold (LTS) neuron;
Neocortex spiking irregular interneuron;
Channel(s):
I Na,p;
I Na,t;
I L high threshold;
I T low threshold;
I A;
I K;
I h;
I_Ks;
I_KD;
Gap Junctions:
Receptor(s):
GabaA;
GabaB;
AMPA;
NMDA;
Gene(s):
Transmitter(s):
Gaba;
Glutamate;
Simulation Environment:
NEURON;
Model Concept(s):
Activity Patterns;
Synchronization;
Active Dendrites;
Implementer(s):
Sidiropoulou, Kyriaki [sidirop at imbb.forth.gr];
Konstantoudaki, Xanthippi [xeniakons at gmail.com];
Search NeuronDB
for information about:
GabaA
;
GabaB
;
AMPA
;
NMDA
;
I Na,p
;
I Na,t
;
I L high threshold
;
I T low threshold
;
I A
;
I K
;
I h
;
I_Ks
;
I_KD
;
Gaba
;
Glutamate
;
Download the displayed file
/
KonstantoudakiEtAl2014
experiment
data
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run
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../i686/special final.hoc -
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