MicrocircuitDB: VTA neurons: Morphofunctional alterations in acute opiates withdrawal (Enrico et al. 2016)

VTA neurons: Morphofunctional alterations in acute opiates withdrawal (Enrico et al. 2016)

Download zip file Auto-launch
Help downloading and running models

Model Information
Model File

Accession:185330

" ... Here we present a biophysical model of a DA VTA neuron based on 3D morphological reconstruction and electrophysiological data, showing how opiates withdrawal-driven morphological and electrophysiological changes could affect the firing rate and discharge pattern...."
Reference:
1 . Enrico P, Migliore M, Spiga S, Mulas G, Caboni F, Diana M (2016) Morphofunctional alterations in ventral tegmental area dopamine neurons in acute and prolonged opiates withdrawal. A computational perspective. Neuroscience 322:195-207 [PubMed]

Citations Citation Browser

Model Information (Click on a link to find other models with that property)

Model Type:	Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Cell Type(s):	Ventral tegmental area dopamine neuron;
Channel(s):
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment:	NEURON;
Model Concept(s):	Activity Patterns; Addiction;
Implementer(s):	Enrico, Paolo [enrico at uniss.it];