Signal integration in a CA1 pyramidal cell (Graham 2001)

 Download zip file   Auto-launch 
Help downloading and running models
Accession:19746
This model investigates signal integration in the dendritic tree of a hippocampal CA1 pyramidal cell when different combinations of active channels are present in the tree (Graham, 2001)
Reference:
1 . Graham BP (2001) Pattern recognition in a compartmental model of a CA1 pyramidal neuron. Network 12:473-92 [PubMed]
Citations  Citation Browser
Model Information (Click on a link to find other models with that property)
Model Type: Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Cell Type(s): Hippocampus CA1 pyramidal GLU cell;
Channel(s): I Potassium;
Gap Junctions:
Receptor(s): AMPA;
Gene(s):
Transmitter(s):
Simulation Environment: NEURON;
Model Concept(s): Active Dendrites;
Implementer(s): Graham, Bruce [B.Graham at cs.stir.ac.uk];
Search NeuronDB for information about:  Hippocampus CA1 pyramidal GLU cell; AMPA; I Potassium;
/* xmenusyn.hoc
   X menu for adding and deleting synapses to dendrites.
   BPG 9-1-01; modified 5-4-05
*/

/* Create menu panel */
proc xmenusyn() {
    xpanel("Excitatory Synapses")
    xvalue("Number of synapses","nsyn",1)
    xvalue("Synaptic conductance (nS)","DE_gmax",1)
    xvalue("NMDA fraction","NMDA_frac",1)
    xvalue("Temporal jitter (msec)","jitter_time",1)
    xvalue("Quantal variance (CV)", "quantal_cv",1)
    xvalue("Conductance scaling", "gsc_flag",1)
    xvalue("Random seed", "my_seed",1)
    xbutton("Update synapses","creatensynDE(layer_SR, nsyn, my_seed)")
    xpanel()
}