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Interneuron Specific 3 Interneuron Model (Guet-McCreight et al, 2016)
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Accession:
223031
In this paper we develop morphologically detailed multi-compartment models of Hippocampal CA1 interneuron specific 3 interneurons using cell current-clamp recordings and dendritic calcium imaging data. In doing so, we developed several variant models, as outlined in the associated README.html file.
Reference:
1 .
Guet-McCreight A, Camiré O, Topolnik L, Skinner FK (2016) Using a Semi-Automated Strategy to Develop Multi-Compartment Models That Predict Biophysical Properties of Interneuron-Specific 3 (IS3) Cells in Hippocampus.
eNeuro
[
PubMed
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Model Information
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Model Type:
Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Hippocampus;
Cell Type(s):
Channel(s):
I Na,t;
I Na,p;
I A;
Gap Junctions:
Receptor(s):
Gene(s):
Kv3.1 KCNC1;
Kv2.1 KCNB1;
Transmitter(s):
Simulation Environment:
NEURON;
Model Concept(s):
Action Potentials;
Active Dendrites;
Activity Patterns;
Depolarization block;
Detailed Neuronal Models;
Ion Channel Kinetics;
Implementer(s):
Guet-McCreight, Alexandre [alexandre.guet.mccreight at mail.utoronto.ca];
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for information about:
I Na,p
;
I Na,t
;
I A
;
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Guet-McCreightEtAl2016
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