MicrocircuitDB: Distance-dependent inhibition in the hippocampus (Strüber et al. 2017)

Distance-dependent inhibition in the hippocampus (Strüber et al. 2017)

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Model File

Accession:229750

Network model of a hippocampal circuit including interneurons and principal cells. Amplitude and decay time course of inhibitory synapses can be systematically changed for different distances between connected cells. Various forms of excitatory drives can be administered to the network including spatially structured input.
Reference:
1 . Strüber M, Sauer JF, Jonas P, Bartos M (2017) Distance-dependent inhibition facilitates focality of gamma oscillations in the dentate gyrus. Nat Commun 8:758 [PubMed]

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Model Information (Click on a link to find other models with that property)

Model Type:	Realistic Network;
Brain Region(s)/Organism:	Dentate gyrus;
Cell Type(s):	Dentate gyrus granule GLU cell; Dentate gyrus basket cell;
Channel(s):
Gap Junctions:	Gap junctions;
Receptor(s):	GabaA; Glutamate;
Gene(s):
Transmitter(s):	Gaba; Glutamate;
Simulation Environment:	NEURON;
Model Concept(s):	Gamma oscillations; Spatio-temporal Activity Patterns;
Implementer(s):	Strüber, Michael [michael_strueber at hotmail.com];

Search NeuronDB for information about: Dentate gyrus granule GLU cell; GabaA; Glutamate; Gaba; Glutamate;

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net_hh_wbsh.mod

net_dd_emodel.hoc

net_dd_imodel.hoc

net_dd_params.hoc

net_dd_procs.hoc

net_dd_vectors.hoc

NEURON {
	POINT_PROCESS gap
	NONSPECIFIC_CURRENT i
	RANGE r, i
	POINTER vgap
}

PARAMETER {
	v (millivolt)
	vgap (millivolt)
	r = 1e10 (megohm)
}

ASSIGNED {
	i (nanoamp)
}

BREAKPOINT {
	i = (v - vgap)/r
}