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Parallel odor processing by mitral and middle tufted cells in the OB (Cavarretta et al 2016, 2018)
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Accession:
240116
"[...] experimental findings suggest that MC and mTC may encode parallel and complementary odor representations. We have analyzed the functional roles of these pathways by using a morphologically and physiologically realistic three-dimensional model to explore the MC and mTC microcircuits in the glomerular layer and deeper plexiform layers. [...]"
Reference:
1 .
Cavarretta F, Burton SD, Igarashi KM, Shepherd GM, Hines ML, Migliore M (2018) Parallel odor processing by mitral and middle tufted cells in the olfactory bulb.
Sci Rep
8
:7625
[
PubMed
]
2 .
Cavarretta F, Marasco A, Hines ML, Shepherd GM, Migliore M (2016) Glomerular and Mitral-Granule Cell Microcircuits Coordinate Temporal and Spatial Information Processing in the Olfactory Bulb.
Front Comput Neurosci
10
:67
[
PubMed
]
Citations
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Model Information
(Click on a link to find other models with that property)
Model Type:
Realistic Network;
Brain Region(s)/Organism:
Olfactory bulb;
Cell Type(s):
Olfactory bulb main tufted middle GLU cell;
Olfactory bulb main interneuron granule MC GABA cell;
Olfactory bulb main interneuron granule TC GABA cell;
Olfactory bulb (accessory) mitral cell;
Olfactory bulb main tufted cell external;
Olfactory bulb short axon cell;
Channel(s):
I A;
I Na,t;
I_Ks;
I K;
Gap Junctions:
Gap junctions;
Receptor(s):
AMPA;
GabaA;
NMDA;
Gene(s):
Transmitter(s):
Glutamate;
Gaba;
Simulation Environment:
NEURON;
Model Concept(s):
Action Potentials;
Action Potential Initiation;
Active Dendrites;
Long-term Synaptic Plasticity;
Synaptic Integration;
Synchronization;
Pattern Recognition;
Spatio-temporal Activity Patterns;
Temporal Pattern Generation;
Sensory coding;
Sensory processing;
Olfaction;
Implementer(s):
Cavarretta, Francesco [francescocavarretta at hotmail.it];
Hines, Michael [Michael.Hines at Yale.edu];
Search NeuronDB
for information about:
Olfactory bulb main interneuron granule MC GABA cell
;
Olfactory bulb main tufted middle GLU cell
;
Olfactory bulb main interneuron granule TC GABA cell
;
GabaA
;
AMPA
;
NMDA
;
I Na,t
;
I A
;
I K
;
I_Ks
;
Gaba
;
Glutamate
;
Download the displayed file
/
modeldb-bulb3d
sim
ampanmda.mod
distrt.mod
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