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CA1 network model for place cell dynamics (Turi et al 2019)
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Model Information
Model File
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Accession:
246546
Biophysical model of CA1 hippocampal region. The model simulates place cells/fields and explores the place cell dynamics as function of VIP+ interneurons.
Reference:
1 .
Turi GF, Li W, Chavlis S, Pandi I, O’Hare J, Priestley JB, Grosmark AD, Liao Z, Ladow M, Zhang JF, Zemelman BV, Poirazi P, Losonczy A (2019) Vasoactive Intestinal Polypeptide-Expressing Interneurons in the Hippocampus Support Goal-Oriented Spatial Learning
Neuron
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Model Information
(Click on a link to find other models with that property)
Model Type:
Realistic Network;
Brain Region(s)/Organism:
Hippocampus;
Mouse;
Cell Type(s):
Hippocampus CA1 pyramidal GLU cell;
Hippocampus CA1 basket cell;
Hippocampus CA1 basket cell - CCK/VIP;
Hippocampus CA1 bistratified cell;
Hippocampus CA1 axo-axonic cell;
Hippocampus CA1 stratum oriens lacunosum-moleculare interneuron ;
Hippocampal CA1 CR/VIP cell;
Channel(s):
I A;
I h;
I K,Ca;
I Calcium;
I Na, leak;
I K,leak;
I M;
Gap Junctions:
Receptor(s):
GabaA;
GabaB;
NMDA;
AMPA;
Gene(s):
Transmitter(s):
Simulation Environment:
NEURON;
Brian;
Model Concept(s):
Place cell/field;
Implementer(s):
Chavlis, Spyridon [schavlis at imbb.forth.gr];
Pandi, Ioanna ;
Search NeuronDB
for information about:
Hippocampus CA1 pyramidal GLU cell
;
GabaA
;
GabaB
;
AMPA
;
NMDA
;
I A
;
I K,leak
;
I M
;
I h
;
I K,Ca
;
I Calcium
;
I Na, leak
;
/
Turi_et_al_2019
AnalysisRawData
background_noise
cells
make_inputs_linear_track
mechanisms
Simulation_Results
ValidationTests
README.txt
Network_locomotion.hoc
Network_prelearning.hoc
Network_reward.hoc
ranstream.hoc
*
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Long time windows from theta modulated inhib. in entorhinal–hippo. loop (Cutsuridis & Poirazi 2015)
Spine head calcium in a CA1 pyramidal cell model (Graham et al. 2014)
The APP in C-terminal domain alters CA1 neuron firing (Pousinha et al 2019)
Translating network models to parallel hardware in NEURON (Hines and Carnevale 2008)
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