Factors contribution to GDP-induced [Cl-]i transients (Lombardi et al 2019)

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Accession:253369
This models are used to evaluate which factors influence the GDP (giant depolarizing potential) induced [Cl-]I transients based on a initial model of P. Jedlicka
Reference:
1 . Lombardi A, Jedlicka P, Luhmann HJ, Kilb W (2019) Interactions Between Membrane Resistance, GABA-A Receptor Properties, Bicarbonate Dynamics and Cl-Transport Shape Activity-Dependent Changes of Intracellular Cl- Concentration Int J of Mol Sci [PubMed]
Citations  Citation Browser
Model Information (Click on a link to find other models with that property)
Model Type: Neuron or other electrically excitable cell; Dendrite; Synapse;
Brain Region(s)/Organism: Mouse; Hippocampus;
Cell Type(s): Hippocampus CA3 pyramidal GLU cell;
Channel(s):
Gap Junctions:
Receptor(s): GabaA;
Gene(s):
Transmitter(s): Gaba;
Simulation Environment: NEURON;
Model Concept(s): Synaptic Plasticity;
Implementer(s):
Search NeuronDB for information about:  Hippocampus CA3 pyramidal GLU cell; GabaA; Gaba;
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LombardiEtAl2019
Isolated_Dendrite_tauNKCC1__Fig9
cldif_CA3_NKCC1_HCO3.mod *
gabaA_Cl_HCO3.mod *
VDpas.mod *
vecevent.mod *
cell_isolated_dendrite.hoc *
cell_soma_dendrite.hoc *
cell_soma_dendrite_1000um.hoc
cell_soma_dendrite_fine.hoc
Freq_PSC.ses
gabaA_Cl_HCO3.o
GABA-Stim_1xPSC_isolated_dendrite_GUI.hoc
GABA-Stim_2xPSC_Spatial_Sum_isolated_dendrite.hoc
GABA-Stim_2xPSC_Spatial_Sum_isolated_dendrite_enlarged_tauNKCC1.hoc
GABA-Stim_3xPSC_isolated_dendrite_GUI.hoc
GABA-Stim_5xPSC_Freq_isolated_dendrite.hoc
GABA-Stim_5xPSC_Freq_isolated_dendrite_back.hoc
GABA-Stim_5xPSC_Freq_isolated_dendrite_enlarged_tauNKCC1.hoc
GABA-Stim_5xPSC_Spatial_isolated_dendrite-Draft.hoc
init_Cldif_isolated_dendrite.hoc
Isolated_Dendrite.ses *
Isolated_Dendrite_Diff_Flux_1xGABA.ses
Isolated_Dendrite_Diff_Flux_3xGABA.ses
Isolated_Dendrite_Diff_Flux_Laptop.ses
start_GABA-Stim_2xPSC_Spatial_Sum_isolated_dendrite.hoc
start_GABA-Stim_2xPSC_Spatial_Sum_isolated_dendrite_enlarged_tauNKCC1.hoc
start_GABA-Stim_5xPSC_Freq_isolated_dendrite.hoc
start_GABA-Stim_5xPSC_Freq_isolated_dendrite_enlarged_tauNKCC1.hoc
start_procedure.hoc
                            
// Start

load_file("nrngui.hoc")
load_file("cell_soma_dendrite_1000um.hoc")
load_file("init_Cldif_isolated_dendrite.hoc")
load_file("Freq_PSC.ses")
load_file("GABA-Stim_2xPSC_Spatial_Sum_isolated_dendrite.hoc")