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Library of biophysically detailed striatal projection neurons (Lindroos and Hellgren Kotaleski 2020)
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Model Information
Model File
Accession:
266775
Library of compartmentalized models used to investigate dendritic integration in striatal projection neurons under neuromodulation.
Reference:
1 .
Lindroos R, Hellgren Kotaleski J (2020) Predicting complex spikes in striatal projection neurons of the direct pathway following neuromodulation by acetylcholine and dopamine.
Eur J Neurosci
[
PubMed
]
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Model Information
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Model Type:
Neuron or other electrically excitable cell;
Synapse;
Brain Region(s)/Organism:
Striatum;
Hippocampus;
Basal ganglia;
Cell Type(s):
Neostriatum medium spiny direct pathway GABA cell;
Neostriatum medium spiny indirect pathway GABA cell;
Striatal projection neuron;
Channel(s):
I M;
I Potassium;
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Acetylcholine;
Dopamine;
Simulation Environment:
NEURON;
Python;
Model Concept(s):
Active Dendrites;
Detailed Neuronal Models;
Neuromodulation;
Synaptic Plasticity;
Activity Patterns;
Soma-dendrite cross-talk;
Implementer(s):
Lindroos, Robert [robert.lindroos at ki.se];
Filipovic, Marko;
Search NeuronDB
for information about:
Neostriatum medium spiny direct pathway GABA cell
;
Neostriatum medium spiny indirect pathway GABA cell
;
I M
;
I Potassium
;
Acetylcholine
;
Dopamine
;
Download the displayed file
/
lib
Libraries
D1_71bestFit_updRheob.pkl
D2_34bestFit_updRheob.pkl
dspn_ACh_factors_v2.json
dspn_DA_factors_v2.json
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