Compartmental model of a mitral cell (Popovic et al. 2005)

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Accession:53435
Usage of a morphologically realistic compartmental model of a mitral cell and data obtained from whole-cell patch-clamp and voltage-imaging experiments in order to explore passive parameter space in which reported low EPSP attenuation is observed.
Reference:
1 . Popovic M, Djurisic M, Zecevic D (2005) Determinants of low EPSP attenuation in primary dendrites of mitral cells: modeling study. Ann N Y Acad Sci 1048:344-8 [PubMed]
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Model Information (Click on a link to find other models with that property)
Model Type: Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Cell Type(s): Olfactory bulb main mitral GLU cell;
Channel(s): I K,leak;
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment: NEURON;
Model Concept(s): Action Potential Initiation; Olfaction;
Implementer(s): Popovic, Marko [tica at ibiss.bg.ac.yu];
Search NeuronDB for information about:  Olfactory bulb main mitral GLU cell; I K,leak;
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anyas2005
model_bf_real_EPSP
EPSPClamp.mod *
avgdiams1.txt *
avgdiams2.txt *
avgdiams3.txt *
avgdiams4.txt *
avgdiams5.txt *
basediams1.txt *
basediams2.txt *
basediams3.txt *
basediams4.txt *
basediams5.txt *
enddiams1.txt *
enddiams2.txt *
enddiams3.txt *
enddiams4.txt *
enddiams5.txt *
epsp.txt *
epsp_soma.txt *
lengths1.txt *
lengths2.txt *
lengths3.txt *
lengths4.txt *
lengths5.txt *
membrane.hoc
morphology.hoc
mosinit.hoc
nltemplate.hoc *
order1.txt *
order2.txt *
order3.txt *
order4.txt *
order5.txt *
parameters.hoc *
xyangles1.txt *
xyangles2.txt *
xyangles3.txt *
xyangles4.txt *
xyangles5.txt *
xyz1.txt *
xyz2.txt *
xyz3.txt *
xyz4.txt *
xyz5.txt *
zangles1.txt *
zangles2.txt *
zangles3.txt *
zangles4.txt *
zangles5.txt *
                            
proc set_membrane() { local Rms
  Cms = $1
  Rms = $2
  Raxial = $3
  forall {
      insert pas
      e_pas = Erest
      g_pas = 1/(Rms)
      Ra = Raxial
      cm = Cms
  }
}
set_membrane(1.18,9600,54)

objref epsp1
tuft_nl.sect[0] epsp1 = new EPSPClamp(0)
epsp1.delay = 36
epsp1.rs=0.1

//objref hpp_stim
//tuft_nl.sect[0] hpp_stim = new IClamp(0)
//hpp_stim.del=100
//hpp_stim.dur=800
//hpp_stim.amp=-0.4