Advanced search
User account
Login
Register
Find models by
Model name
First author
Each author
Find models for
Brain region
Concept
Find models of
Realistic Microcircuits
Connectionist Networks
CA1 pyramidal neurons: binding properties and the magical number 7 (Migliore et al. 2008)
Download zip file
Auto-launch
Help downloading and running models
Model Information
Model File
Model Views
Accession:
87535
NEURON files from the paper: Single neuron binding properties and the magical number 7, by M. Migliore, G. Novara, D. Tegolo, Hippocampus, in press (2008). In an extensive series of simulations with realistic morphologies and active properties, we demonstrate how n radial (oblique) dendrites of these neurons may be used to bind n inputs to generate an output signal. The results suggest a possible neural code as the most effective n-ple of dendrites that can be used for short-term memory recollection of persons, objects, or places. Our analysis predicts a straightforward physiological explanation for the observed puzzling limit of about 7 short-term memory items that can be stored by humans.
Reference:
1 .
Migliore M, Novara G, Tegolo D (2008) Single neuron binding properties and the magical number 7.
Hippocampus
18
:1122-30
[
PubMed
]
Citations
Citation Browser
Model Information
(Click on a link to find other models with that property)
Model Type:
Dendrite;
Brain Region(s)/Organism:
Cell Type(s):
Hippocampus CA1 pyramidal GLU cell;
Channel(s):
I A;
I K;
I h;
I Sodium;
Gap Junctions:
Receptor(s):
AMPA;
Gene(s):
Transmitter(s):
Simulation Environment:
NEURON;
Model Concept(s):
Pattern Recognition;
Activity Patterns;
Dendritic Action Potentials;
Coincidence Detection;
Spatio-temporal Activity Patterns;
Active Dendrites;
Detailed Neuronal Models;
Action Potentials;
Synaptic Integration;
Working memory;
Learning;
Action Selection/Decision Making;
Implementer(s):
Migliore, Michele [Michele.Migliore at Yale.edu];
Search NeuronDB
for information about:
Hippocampus CA1 pyramidal GLU cell
;
AMPA
;
I A
;
I K
;
I h
;
I Sodium
;
/
magical7
File not selected
<- Select file from this column.
Load Model View