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Adler EM, Yaari Y, David G, Selzer ME (1986) Frequency-dependent action of phenytoin on lamprey spinal axons. Brain Res 362:271-80 [PubMed] Ayala GF, Lin S, Johnston D (1977) The mechanism of action of diphenylhydantoin or invertebrate neurons. I. Effects on basic membrane properties. Brain Res 121:245-58 [PubMed] Carnevale NT, Hines ML (2006) The NEURON Book [Journal] Destexhe A, Rudolph M, Fellous JM, Sejnowski TJ (2001) Fluctuating synaptic conductances recreate in vivo-like activity in neocortical neurons. Neuroscience 107:13-24 [PubMed] Destexhe A, Rudolph M, Paré D (2003) The high-conductance state of neocortical neurons in vivo. Nat Rev Neurosci 4:739-51 [Journal] [PubMed] Dudek FE, Sutula TP (2007) Epileptogenesis in the dentate gyrus: a critical perspective. Prog Brain Res 163:755-73 [Journal] [PubMed] Dyhrfjeld-Johnsen J, Santhakumar V, Morgan RJ, Huerta R, Tsimring L, Soltesz I (2007) Topological determinants of epileptogenesis in large-scale structural and functional models of the dentate gyrus derived from experimental data. J Neurophysiol 97:1566-87 [Journal] [PubMed]
Escayg A, Goldin AL (2010) Sodium channel SCN1A and epilepsy: mutations and mechanisms. Epilepsia 51:1650-8 [Journal] [PubMed] Fellous JM, Rudolph M, Destexhe A, Sejnowski TJ (2003) Synaptic background noise controls the input/output characteristics of single cells in an in vitro model of in vivo activity. Neuroscience 122:811-29 [PubMed] Heinemann U, Beck H, Dreier JP, Ficker E, Stabel J, Zhang CL (1992) The dentate gyrus as a regulated gate for the propagation of epileptiform activity. Epilepsy Res Suppl 7:273-80 [PubMed] Hille B (2001) Ionic Channels of Excitable Membranes HODGKIN AL, HUXLEY AF (1952) A quantitative description of membrane current and its application to conduction and excitation in nerve. J Physiol 117:500-44 [Journal] [PubMed] Howard AL, Neu A, Morgan RJ, Echegoyen JC, Soltesz I (2007) Opposing modifications in intrinsic currents and synaptic inputs in post-traumatic mossy cells: evidence for single-cell homeostasis in a hyperexcitable network. J Neurophysiol 97:2394-409 [Journal] [PubMed] Johnston D, Sms WU (1994) Foundations of cellular neurophysiology Kuo CC, Bean BP (1994) Slow binding of phenytoin to inactivated sodium channels in rat hippocampal neurons. Mol Pharmacol 46:716-25 [PubMed] Kuo CC, Chen RS, Lu L, Chen RC (1997) Carbamazepine inhibition of neuronal Na+ currents: quantitative distinction from phenytoin and possible therapeutic implications. Mol Pharmacol 51:1077-83 [PubMed] Lerman P (1986) Seizures induced or aggravated by anticonvulsants. Epilepsia 27:706-10 [PubMed] Liu L, Zheng T, Morris MJ, Wallengren C, Clarke AL, Reid CA, Petrou S, O'Brien TJ (2006) The mechanism of carbamazepine aggravation of absence seizures. J Pharmacol Exp Ther 319:790-8 [Journal] [PubMed] Lothman EW, Stringer JL, Bertram EH (1992) The dentate gyrus as a control point for seizures in the hippocampus and beyond. Epilepsy Res Suppl 7:301-13 [PubMed] McLean MJ, Macdonald RL (1983) Multiple actions of phenytoin on mouse spinal cord neurons in cell culture. J Pharmacol Exp Ther 227:779-89 [PubMed] Meisler MH, Kearney JA (2005) Sodium channel mutations in epilepsy and other neurological disorders. J Clin Invest 115:2010-7 [Journal] [PubMed] Morgan RJ, Soltesz I (2008) Nonrandom connectivity of the epileptic dentate gyrus predicts a major role for neuronal hubs in seizures. Proc Natl Acad Sci U S A 105:6179-84 [Journal] [PubMed]
Nardi A, Damann N, Hertrampf T, Kless A (2012) Advances in targeting voltage-gated sodium channels with small molecules. ChemMedChem 7:1712-40 [Journal] [PubMed] Patlak J (1991) Molecular kinetics of voltage-dependent Na+ channels. Physiol Rev 71:1047-80 [Journal] [PubMed] Perucca E, Gram L, Avanzini G, Dulac O (1998) Antiepileptic drugs as a cause of worsening seizures. Epilepsia 39:5-17 [PubMed] Quilichini PP, Diabira D, Chiron C, Milh M, Ben-Ari Y, Gozlan H (2003) Effects of antiepileptic drugs on refractory seizures in the intact immature corticohippocampal formation in vitro. Epilepsia 44:1365-74 [PubMed] Santhakumar V, Aradi I, Soltesz I (2005) Role of mossy fiber sprouting and mossy cell loss in hyperexcitability: a network model of the dentate gyrus incorporating cell types and axonal topography. J Neurophysiol 93:437-53 [Journal] [PubMed]
Sherwin AL, Wisen AA, Sokolowski CD (1973) Anticonvulsant drugs in human epileptogenic brain. Correlation of phenobarbital and diphenylhydantoin levels with plasma. Arch Neurol 29:73-7 [PubMed] Staley KJ, Otis TS, Mody I (1992) Membrane properties of dentate gyrus granule cells: comparison of sharp microelectrode and whole-cell recordings. J Neurophysiol 67:1346-58 [Journal] [PubMed] Strandjord RE, Johannessen SI (1980) Single-drug therapy with carbamazepine in patients with epilepsy: serum levels and clinical effect. Epilepsia 21:655-52 [PubMed] Stringer JL, Lothman EW (1992) Bilateral maximal dentate activation is critical for the appearance of an afterdischarge in the dentate gyrus. Neuroscience 46:309-14 [PubMed] Thomas EA, Petrou S (2008) Case for realistic modeling in understanding seizures. Expert Rev Neurother 8:1771-3 [Journal] [PubMed] Thomas EA, Reid CA, Berkovic SF, Petrou S (2009) Prediction by modeling that epilepsy may be caused by very small functional changes in ion channels. Arch Neurol 66:1225-32 [Journal] [PubMed]
Thomas EA, Reid CA, Petrou S (2010) Mossy fiber sprouting interacts with sodium channel mutations to increase dentate gyrus excitability. Epilepsia 51:136-45 [Journal] [PubMed]
Thomas EA, Xu R, Petrou S (2007) Computational analysis of the R85C and R85H epilepsy mutations in Na+ channel beta1 subunits. Neuroscience 147:1034-46 [Journal] [PubMed] | Morris G, Leite M, Kullmann DM, Pavlov I, Schorge S, Lignani G (2017) Activity Clamp Provides Insights into Paradoxical Effects of the Anti-Seizure Drug Carbamazepine. J Neurosci 37:5484-5495 [Journal] [PubMed] |