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Lytton WW, Omurtag A (2007) Tonic-clonic transitions in computer simulation. J Clin Neurophysiol 24:175-81 [PubMed]

  • Tonic-clonic transitions in a seizure simulation (Lytton and Omurtag 2007)

References and models cited by this paper

References and models that cite this paper

Bush PC, Prince DA, Miller KD (1999) Increased pyramidal excitability and NMDA conductance can explain posttraumatic epileptogenesis without disinhibition: a model. J Neurophysiol 82:1748-58 [Journal] [PubMed]
  • Cortical network model of posttraumatic epileptogenesis (Bush et al 1999) [Model]
Dudek FE, Patrylo PR, Wuarin JP (1999) Mechanisms of neuronal synchronization during epileptiform activity. Adv Neurol 79:699-708 [PubMed]
Garcia Dominguez L, Wennberg RA, Gaetz W, Cheyne D, Snead OC, Perez Velazquez JL (2005) Enhanced synchrony in epileptiform activity? Local versus distant phase synchronization in generalized seizures. J Neurosci 25:8077-84 [Journal] [PubMed]
Hereld M, Stevens RL, Teller J, Drongelen W (2005) Large neural simulations on large parallel computers Int J Bioelectromagn 7:44-46
Lytton WW (2002) From Computer To Brain
Lytton WW (2006) Neural Query System: Data-mining from within the NEURON simulator. Neuroinformatics 4:163-76 [Journal] [PubMed]
  • Neural Query System NQS Data-Mining From Within the NEURON Simulator (Lytton 2006) [Model]
Lytton WW, Hellman KM, Sutula TP (1998) Computer models of hippocampal circuit changes of the kindling model of epilepsy. Artif Intell Med 13:81-97 [PubMed]
Lytton WW, Sejnowski TJ (1991) Simulations of cortical pyramidal neurons synchronized by inhibitory interneurons. J Neurophysiol 66:1059-79 [Journal] [PubMed]
Lytton WW, Stewart M (2005) A rule-based firing model for neural networks Int J Bioelectromagn 7:47-50
Lytton WW, Stewart M (2006) Rule-based firing for network simulations. Neurocomputing 69:1160-1164
Meeren HK, Pijn JP, Van Luijtelaar EL, Coenen AM, Lopes da Silva FH (2002) Cortical focus drives widespread corticothalamic networks during spontaneous absence seizures in rats. J Neurosci 22:1480-95 [PubMed]
Omurtag A, Knight BW, Sirovich L (2000) On the simulation of large populations of neurons. J Comput Neurosci 8:51-63 [PubMed]
Sirovich L, Omurtag A, Lubliner K (2006) Dynamics of neural populations: stability and synchrony. Network 17:3-29 [Journal] [PubMed]
Traub RD, Jefferys JG, Whittington MA (1994) Enhanced NMDA conductance can account for epileptiform activity induced by low Mg2+ in the rat hippocampal slice. J Physiol 478 Pt 3:379-93 [PubMed]
Van Drongelen W, Koch H, Marcuccilli C, Pena F, Ramirez JM (2003) Synchrony levels during evoked seizure-like bursts in mouse neocortical slices. J Neurophysiol 90:1571-80 [Journal] [PubMed]
van Drongelen W, Lee HC, Hereld M, Chen Z, Elsen FP, Stevens RL (2005) Emergent epileptiform activity in neural networks with weak excitatory synapses. IEEE Trans Neural Syst Rehabil Eng 13:236-41 [Journal] [PubMed]
Xie X, Lancaster B, Peakman T, Garthwaite J (1995) Interaction of the antiepileptic drug lamotrigine with recombinant rat brain type IIA Na+ channels and with native Na+ channels in rat hippocampal neurones. Pflugers Arch 430:437-46 [PubMed]
Chadderdon GL, Neymotin SA, Kerr CC, Lytton WW (2012) Reinforcement learning of targeted movement in a spiking neuronal model of motor cortex. PLoS One 7:e47251 [Journal] [PubMed]
  • Reinforcement learning of targeted movement (Chadderdon et al. 2012) [Model]
Kerr CC, Neymotin SA, Chadderdon GL, Fietkiewicz CT, Francis JT, Lytton WW (2012) Electrostimulation as a prosthesis for repair of information flow in a computer model of neocortex. IEEE Trans Neural Syst Rehabil Eng 20:153-60 [Journal] [PubMed]
  • Prosthetic electrostimulation for information flow repair in a neocortical simulation (Kerr 2012) [Model]
Kerr CC, Van Albada SJ, Neymotin SA, Chadderdon GL, Robinson PA, Lytton WW (2013) Cortical information flow in Parkinson's disease: a composite network/field model. Front Comput Neurosci 7:39 [Journal] [PubMed]
  • Composite spiking network/neural field model of Parkinsons (Kerr et al 2013) [Model]
Lytton WW, Neymotin SA, Wester JC, Contreras D (2011) Neocortical simulation for epilepsy surgery guidance: Localization and intervention Computational Surgery and Dual Training [Journal]
  • Computational Surgery (Lytton et al. 2011) [Model]
Neymotin S, Uhlrich DJ, Manning KA, Lytton WW (2008) Data mining of time-domain features from neural extracellular field data Applic. of Comput. Intel. in Bioinf. and Biomed.: Current Trends and Open Problems 151:119-140 [Journal]
  • NEURON interfaces to MySQL and the SPUD feature extraction algorithm (Neymotin et al. 2008) [Model]
Neymotin SA, Chadderdon GL, Kerr CC, Francis JT, Lytton WW (2013) Reinforcement learning of two-joint virtual arm reaching in a computer model of sensorimotor cortex. Neural Comput 25:3263-93 [Journal] [PubMed]
  • Sensorimotor cortex reinforcement learning of 2-joint virtual arm reaching (Neymotin et al. 2013) [Model]
Neymotin SA, Dura-Bernal S, Lakatos P, Sanger TD, Lytton WW (2016) Multitarget Multiscale Simulation for Pharmacological Treatment of Dystonia in Motor Cortex. Front Pharmacol 7:157 [Journal] [PubMed]
  • Multitarget pharmacology for Dystonia in M1 (Neymotin et al 2016) [Model]
Neymotin SA, Jacobs KM, Fenton AA, Lytton WW (2011) Synaptic information transfer in computer models of neocortical columns. J Comput Neurosci 30:69-84 [Journal] [PubMed]
  • Synaptic information transfer in computer models of neocortical columns (Neymotin et al. 2010) [Model]
Neymotin SA, Lee H, Park E, Fenton AA, Lytton WW (2011) Emergence of physiological oscillation frequencies in a computer model of neocortex. Front Comput Neurosci 5:19 [Journal] [PubMed]
  • Emergence of physiological oscillation frequencies in neocortex simulations (Neymotin et al. 2011) [Model]
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