Citation Relationships

Legends: Link to a Model Reference cited by multiple papers

Somjen GG, Kager H, Wadman WJ (2008) Computer simulations of neuron-glia interactions mediated by ion flux. J Comput Neurosci 25:349-65 [PubMed]

   Computer simulations of neuron-glia interactions mediated by ion flux (Somjen et al. 2008)

References and models cited by this paper

References and models that cite this paper

Amzica F, Massimini M, Manfridi A (2002) Spatial buffering during slow and paroxysmal sleep oscillations in cortical networks of glial cells in vivo. J Neurosci 22:1042-53 [PubMed]
Anderson WW, Lewis DV, Swartzwelder HS, Wilson WA (1986) Magnesium-free medium activates seizure-like events in the rat hippocampal slice. Brain Res 398:215-9 [PubMed]
Ballanyi K, Grafe P, ten Bruggencate G (1987) Ion activities and potassium uptake mechanisms of glial cells in guinea-pig olfactory cortex slices. J Physiol 382:159-74 [PubMed]
Barres BA, Chun LL, Corey DP (1990) Ion channels in vertebrate glia. Annu Rev Neurosci 13:441-74 [Journal] [PubMed]
Binder DK, Steinhäuser C (2006) Functional changes in astroglial cells in epilepsy. Glia 54:358-68 [Journal] [PubMed]
Bordey A, Sontheimer H (1997) Postnatal development of ionic currents in rat hippocampal astrocytes in situ. J Neurophysiol 78:461-77 [Journal] [PubMed]
Boyle PJ, Conway EJ (1941) Potassium accumulation in muscle and associated changes. J Physiol 100:1-63 [PubMed]
Brockhaus J, Ballanyi K, Smith JC, Richter DW (1993) Microenvironment of respiratory neurons in the in vitro brainstem-spinal cord of neonatal rats. J Physiol 462:421-45 [PubMed]
Calvin WH, Sypert GW (1976) Fast and slow pyramidal tract neurons: an intracellular analysis of their contrasting repetitive firing properties in the cat. J Neurophysiol 39:420-34 [Journal] [PubMed]
Connors B, Dray A, Fox P, Hilmy M, Somjen G (1979) LSD's effect on neuron populations in visual cortex gauged by transient responses of extracellular potassium evoked by optical stimuli. Neurosci Lett 13:147-50 [PubMed]
Connors BW, Gutnick MJ (1990) Intrinsic firing patterns of diverse neocortical neurons. Trends Neurosci 13:99-104 [PubMed]
Cordingley GE, Somjen GG (1978) The clearing of excess potassium from extracellular space in spinal cord and cerebral cortex. Brain Res 151:291-306 [PubMed]
D'Ambrosio R, Wenzel J, Schwartzkroin PA, McKhann GM, Janigro D (1998) Functional specialization and topographic segregation of hippocampal astrocytes. J Neurosci 18:4425-38 [PubMed]
Dietzel I, Heinemann U (1986) Dynamic variations of the brain cell microenvironment in relation to neuronal hyperactivity. Ann N Y Acad Sci 481:72-86 [PubMed]
Dietzel I, Heinemann U, Hofmeier G, Lux HD (1980) Transient changes in the size of the extracellular space in the sensorimotor cortex of cats in relation to stimulus-induced changes in potassium concentration. Exp Brain Res 40:432-9 [PubMed]
Dietzel I, Heinemann U, Lux HD (1989) Relations between slow extracellular potential changes, glial potassium buffering, and electrolyte and cellular volume changes during neuronal hyperactivity in cat brain. Glia 2:25-44 [Journal] [PubMed]
Duffy S, Fraser DD, Macvicar BA (1995) Potassium channels Neuroglia, Kettenmann H:Ransom BR, ed. pp.185
Fernandez FR, Engbers JD, Turner RW (2007) Firing dynamics of cerebellar purkinje cells. J Neurophysiol 98:278-94 [Journal] [PubMed]
Fertziger AP, Ranck JB (1970) Potassium accumulation in interstitial space during epileptiform seizures. Exp Neurol 26:571-85 [PubMed]
FRANKENHAEUSER B, HODGKIN AL (1956) The after-effects of impulses in the giant nerve fibres of Loligo. J Physiol 131:341-76 [PubMed]
Gardner-Medwin AR (1983) Analysis of potassium dynamics in mammalian brain tissue. J Physiol 335:393-426 [PubMed]
Gnatenco C, Han J, Snyder AK, Kim D (2002) Functional expression of TREK-2 K+ channel in cultured rat brain astrocytes. Brain Res 931:56-67 [PubMed]
GREEN JD (1964) THE HIPPOCAMPUS. Physiol Rev 44:561-608 [Journal] [PubMed]
Green JD, Petsche H (1961) Hippocampal electrical activity IV Abnormal electrical activity Electroenceph Clin Neurophysiol 13:868-879
Hansen AJ, Olsen CE (1980) Brain extracellular space during spreading depression and ischemia. Acta Physiol Scand 108:355-65 [Journal] [PubMed]
Heinemann U, Lux HD (1975) Undershoots following stimulus-induced rises of extracellular potassium concentration in cerebral cortex of cat. Brain Res 93:63-76 [PubMed]
Heinemann U, Lux HD (1977) Ceiling of stimulus induced rises in extracellular potassium concentration in the cerebral cortex of cat. Brain Res 120:231-49 [PubMed]
Henn FA, Haljamäe H, Hamberger A (1972) Glial cell function: active control of extracellular K + concentration. Brain Res 43:437-43 [PubMed]
Herreras O, Somjen GG (1993) Effects of prolonged elevation of potassium on hippocampus of anesthetized rats. Brain Res 617:194-204 [PubMed]
Hertz L (1973) Ion Effects on Metabolism in the Adult Mammalian Brain in vitro. Evidence of a Potassium-induced Stimulation of Active Uptake of KCl into Neuroglial Cells dissertation
Hertz L (1978) An intense potassium uptake into astrocytes, its further enhancement by high concentrations of potassium, and its possible involvement in potassium homeostasis at the cellular level. Brain Res 145:202-8 [PubMed]
Izhikevich EM (2007) Dynamical Systems in Neuroscience: The Geometry of Excitability and Bursting [Journal]
   Artificial neuron model (Izhikevich 2003, 2004, 2007) [Model]
Jefferys JG, Haas HL (1982) Synchronized bursting of CA1 hippocampal pyramidal cells in the absence of synaptic transmission. Nature 300:448-50 [PubMed]
Jensen MS, Azouz R, Yaari Y (1994) Variant firing patterns in rat hippocampal pyramidal cells modulated by extracellular potassium. J Neurophysiol 71:831-9 [Journal] [PubMed]
Jing J, Aitken PG, Somjen GG (1991) Lasting neuron depression induced by high potassium and its prevention by low calcium and NMDA receptor blockade. Brain Res 557:177-83 [PubMed]
Jing J, Aitken PG, Somjen GG (1994) Interstitial volume changes during spreading depression (SD) and SD-like hypoxic depolarization in hippocampal tissue slices. J Neurophysiol 71:2548-51 [Journal] [PubMed]
Kager H, Wadman WJ, Somjen GG (2000) Simulated seizures and spreading depression in a neuron model incorporating interstitial space and ion concentrations. J Neurophysiol 84:495-512 [Journal] [PubMed]
Kager H, Wadman WJ, Somjen GG (2002) Conditions for the triggering of spreading depression studied with computer simulations. J Neurophysiol 88:2700-12 [Journal] [PubMed]
Kager H, Wadman WJ, Somjen GG (2007) Seizure-like afterdischarges simulated in a model neuron. J Comput Neurosci 22:105-28 [Journal] [PubMed]
KANDEL ER, SPENCER WA (1961) Electrophysiological properties of an archicortical neuron. Ann N Y Acad Sci 94:570-603 [PubMed]
Kawasaki K, Czéh G, Somjen GG (1988) Prolonged exposure to high potassium concentration results in irreversible loss of synaptic transmission in hippocampal tissue slices. Brain Res 457:322-9 [PubMed]
Kimelberg HK (2004) The problem of astrocyte identity. Neurochem Int 45:191-202 [Journal] [PubMed]
Kivi A, Lehmann TN, Kovács R, Eilers A, Jauch R, Meencke HJ, von Deimling A, Heinemann U, Gabriel S (2000) Effects of barium on stimulus-induced rises of [K+]o in human epileptic non-sclerotic and sclerotic hippocampal area CA1. Eur J Neurosci 12:2039-48 [PubMed]
Kofuji P, Newman EA (2004) Potassium buffering in the central nervous system. Neuroscience 129:1045-56 [Journal] [PubMed]
Konnerth A, Heinemann U, Yaari Y (1986) Nonsynaptic epileptogenesis in the mammalian hippocampus in vitro. I. Development of seizurelike activity in low extracellular calcium. J Neurophysiol 56:409-23 [Journal] [PubMed]
Krnjevic K, Morris ME, Reiffenstein RJ (1982) Stimulation-evoked changes in extracellular K+ and Ca2+ in pyramidal layers of the rat's hippocampus. Can J Physiol Pharmacol 60:1643-57 [PubMed]
Krnjevic K, Schwartz S (1967) Some properties of unresponsive cells in the cerebral cortex. Exp Brain Res 3:306-19 [PubMed]
Kuffler SW, Nicholls JG (1966) The physiology of neuroglial cells. Ergeb Physiol 57:1-90 [PubMed]
Lothman E, Lamanna J, Cordingley G, Rosenthal M, Somjen G (1975) Responses of electrical potential, potassium levels, and oxidative metabolic activity of the cerebral neocortex of cats. Brain Res 88:15-36 [PubMed]
Lux HD (1973) Kaliumaktivitt im Hirngewebe. Untersuchungen zum Krampfproblem Mitteilungen Max Planck Gesellsch 1:34-52
Matthias K, Kirchhoff F, Seifert G, Hüttmann K, Matyash M, Kettenmann H, Steinhäuser C (2003) Segregated expression of AMPA-type glutamate receptors and glutamate transporters defines distinct astrocyte populations in the mouse hippocampus. J Neurosci 23:1750-8 [PubMed]
Moody WJ, Futamachi KJ, Prince DA (1974) Extracellular potassium activity during epileptogenesis. Exp Neurol 42:248-63 [PubMed]
Neusch C, Papadopoulos N, Müller M, Maletzki I, Winter SM, Hirrlinger J, Handschuh M, Bähr M, Richter DW, Kirchhoff F, Hülsmann S (2006) Lack of the Kir4.1 channel subunit abolishes K+ buffering properties of astrocytes in the ventral respiratory group: impact on extracellular K+ regulation. J Neurophysiol 95:1843-52 [Journal] [PubMed]
Newman EA (1984) Regional specialization of retinal glial cell membrane. Nature 309:155-7 [PubMed]
Newman EA (1995) Glial cell regulation of extracellular potassium Neuroglia, Kettenman H:Ransom BR, ed. pp.717
Nicholson C, Rice ME (1988) Use of ion selective microelectrodes and voltametric microsensors to study brain cell microenvironment Neuromethods, Boulton AA:Baker GB:Walz W, ed. pp.247
Orkand RK, Nicholls JG, Kuffler SW (1966) Effect of nerve impulses on the membrane potential of glial cells in the central nervous system of amphibia. J Neurophysiol 29:788-806 [Journal] [PubMed]
Paulson OB, Newman EA (1987) Does the release of potassium from astrocyte endfeet regulate cerebral blood flow? Science 237:896-8 [PubMed]
Picker S, Pieper CF, Goldring S (1981) Glial membrane potentials and their relationship to [K+]o in man and guinea pig. A comparative study of intracellularly marked normal, reactive, and neoplastic glia. J Neurosurg 55:347-63 [Journal] [PubMed]
Rutecki PA, Lebeda FJ, Johnston D (1985) Epileptiform activity induced by changes in extracellular potassium in hippocampus. J Neurophysiol 54:1363-74 [Journal] [PubMed]
Rybak IA, Shevtsova NA, St-John WM, Paton JF, Pierrefiche O (2003) Endogenous rhythm generation in the pre-Bötzinger complex and ionic currents: modelling and in vitro studies. Eur J Neurosci 18:239-57 [PubMed]
Siegenbeek van heukelom J (1994) The role of the potassium inward rectifier in defining cell membrane potentials in low potassium media, analyzed by computer simulation. Biophysical Chemistry 50:345-360
Sík A, Smith RL, Freund TF (2000) Distribution of chloride channel-2-immunoreactive neuronal and astrocytic processes in the hippocampus. Neuroscience 101:51-65 [PubMed]
Singer W, Lux HD (1975) Extracellular potassium gradients and visual receptive fields in the cat striate cortex. Brain Res 96:378-83 [PubMed]
Somjen GG (1975) Electrophysiology of neuroglia. Annu Rev Physiol 37:163-90 [Journal] [PubMed]
Somjen GG (2004) Ions in the brain: Normal function, seizures and stroke
Somjen GG, Kager H, Wadman WJ (2004) Potassium regulation and simulated seizures in a neuron-glia model Society of Neuroscience Abstracts 228.11
Somjen GG, Kager H, Wadman WJ (In press) Simulated seizures and spreading depression 2nd Meet Fed Eur Neurosci Soc
Sypert GW, Ward AA (1974) Changes in extracellular potassium activity during neocortical propagated seizures. Exp Neurol 45:19-41 [PubMed]
Trachtenberg MC, Pollen DA (1970) Neuroglia: biophysical properties and physiologic function. Science 167:1248-52 [PubMed]
Traynelis SF, Dingledine R (1988) Potassium-induced spontaneous electrographic seizures in the rat hippocampal slice. J Neurophysiol 59:259-76 [Journal] [PubMed]
Walz W (2000) Role of astrocytes in the clearance of excess extracellular potassium. Neurochem Int 36:291-300 [PubMed]
Walz W (2002) Chloride/anion channels in glial cell membranes. Glia 40:1-10 [Journal] [PubMed]
Walz W, Juurlink BHJ (2002) Homeostatic properties of astrocytes The Neuronal Environment. Brain Homeostasis in Health and Disease, Walz W, ed. pp.159
Xiong ZQ, Stringer JL (2000) Sodium pump activity, not glial spatial buffering, clears potassium after epileptiform activity induced in the dentate gyrus. J Neurophysiol 83:1443-51 [Journal] [PubMed]
Yan Y, Dempsey RJ, Sun D (2001) Expression of Na(+)-K(+)-Cl(-) cotransporter in rat brain during development and its localization in mature astrocytes. Brain Res 911:43-55 [PubMed]
Zhou M, Kimelberg HK (2000) Freshly isolated astrocytes from rat hippocampus show two distinct current patterns and different [K(+)](o) uptake capabilities. J Neurophysiol 84:2746-57 [Journal] [PubMed]
Zuckermann EC, Glaser GH (1970) Activation of experimental epileptogenic foci. Action of increased K+ in extracellular spaces of the brain. Arch Neurol 23:358-64 [PubMed]
Barreto E, Cressman JR (2011) Ion concentration dynamics as a mechanism for neuronal bursting. J Biol Phys 37:361-73 [Journal] [PubMed]
   Ion concentration dynamics as a mechanism for neuronal bursting (Barreto & Cressman 2011) [Model]
Conte C, Lee R, Sarkar M, Terman D (2018) A mathematical model of recurrent spreading depolarizations. J Comput Neurosci 44:203-217 [Journal] [PubMed]
   A model for recurrent spreading depolarizations (Conte et al. 2017) [Model]
Gentiletti D, Suffczynski P, Gnatkovsky V, de Curtis M (2017) Changes of Ionic Concentrations During Seizure Transitions - A Modeling Study. Int J Neural Syst 27:1750004 [Journal] [PubMed]
   Changes of ionic concentrations during seizure transitions (Gentiletti et al. 2016) [Model]
Hübel N, Dahlem MA (2014) Dynamics from seconds to hours in Hodgkin-Huxley model with time-dependent ion concentrations and buffer reservoirs. PLoS Comput Biol 10:e1003941 [Journal] [PubMed]
   Hodgkin-Huxley with dynamic ion concentrations (Hubel and Dahlem, 2014) [Model]
Kager H, Wadman WJ, Somjen GG (2007) Seizure-like afterdischarges simulated in a model neuron. J Comput Neurosci 22:105-28 [Journal] [PubMed]
Øyehaug L, Østby I, Lloyd CM, Omholt SW, Einevoll GT (2012) Dependence of spontaneous neuronal firing and depolarisation block on astroglial membrane transport mechanisms. J Comput Neurosci 32:147-65 [Journal] [PubMed]
   Dependence of neuronal firing on astroglial membrane transport mechanisms (Oyehaug et al 2012) [Model]
Somjen GG, Kager H, Wadman WJ (2009) Calcium sensitive non-selective cation current promotes seizure-like discharges and spreading depression in a model neuron. J Comput Neurosci 26:139-47 [Journal] [PubMed]
(87 refs)