Models that contain the Implementer : Balbi, Pietro [piero.balbi at fsm.it]

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    Models   Description
1.  A single kinetic model for all human voltage-gated sodium channels (Balbi et al, 2017)
Code for simulating macroscopic currents of sodium channels (Nav1.1. to Nav1.9), by means of a single kinetic model. Intensity-voltage curves, normalized conductance-voltage relationship, steady-state availability and recovery from inactivation are simulated.
2.  Axon-somatic back-propagation in a detailed model of cat spinal motoneuron (Balbi et al, 2015)
Morphologically detailed conductance-based models of cat spinal alpha motoneurons have been developed, with the aim to reproduce and clarify some aspects of the electrophysiological behavior of the antidromic axon-somatic spike propagation. Fourteen 3D morphologically detailed somata and dendrites of cat spinal alpha motoneurons have been imported from an open-access web-based database of neuronal morphologies, NeuroMorpho.org, and instantiated in neurocomputational models.
3.  Recurrent discharge in a reduced model of cat spinal motoneuron (Balbi et al, 2013)
Following a distal stimulation of a motor fibre, only a fraction of spinal motoneurons are able to produce a re-excitation of the initial segment leading to an orthodromically conducted action potential, known as recurrent discharge. In order to show the reciprocal interplay of the axonal initial segment and the soma leading to recurrent discharge in detail, a reduced model of a cat spinal motoneuron was developed.

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