| || Models ||Description|
Cancelling redundant input in ELL pyramidal cells (Bol et al. 2011)
||The paper investigates the property of the electrosensory lateral line lobe (ELL) of the brain of weakly electric fish to cancel predictable stimuli. Electroreceptors on the skin encode all signals in their firing activity, but superficial pyramidal (SP) cells in the ELL that receive this feedforward input do not respond to constant sinusoidal signals. This cancellation putatively occurs using a network of feedback delay lines and burst-induced synaptic plasticity between the delay lines and the SP cell that learns to cancel the redundant input. Biologically, the delay lines are parallel fibres from cerebellar-like granule cells in the eminentia granularis posterior.
A model of this network (e.g. electroreceptors, SP cells, delay lines and burst-induced plasticity) was constructed to test whether the current knowledge of how the network operates is sufficient to cancel redundant stimuli.
Reward modulated STDP (Legenstein et al. 2008)
This article provides tools for an analytic treatment of reward-modulated
STDP, which allows us to predict under which conditions reward-modulated STDP will achieve a desired learning
These analytical results imply that neurons can learn through reward-modulated STDP to classify not only spatial but
also temporal firing patterns of presynaptic neurons.
They also can learn to respond to specific presynaptic firing patterns
with particular spike patterns.
Finally, the resulting learning theory predicts that even difficult credit-assignment problems,
where it is very hard to tell which synaptic weights should be modified in order to increase the global reward for the system,
can be solved in a self-organizing manner through reward-modulated STDP.
This yields an explanation for a fundamental
experimental result on biofeedback in monkeys by Fetz and Baker.
In this experiment monkeys were rewarded for
increasing the firing rate of a particular neuron in the cortex and were able to solve this extremely difficult credit assignment
In addition our model
demonstrates that reward-modulated STDP can be applied to all synapses in a large recurrent neural network without
endangering the stability of the network dynamics."