| Models | Description |
1. |
Allen Institute: Ntsr1-Cre VISp layer 4 472430904
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This is an Allen Cell Types Database model of a Ntsr1-Cre neuron from layer 6a of the mouse primary visual cortex. The model was based on a traced morphology after filling the cell with biocytin and optimized using experimental electrophysiology data recorded from the same cell. The electrophysiology data was collected in a highly standardized way to facilitate comparison across all cells in the database. The model was optimized by a genetic algorithm that adjusted the densities of conductances placed at the soma to match experimentally-measured features of action potential firing. Data and models from the Allen Cell Types Database are made available to the community under the Allen Institute's Terms of Use and Citation Policy. |
2. |
Systematic integration of data into multi-scale models of mouse primary V1 (Billeh et al 2020)
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"Highlights
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Two network models of the mouse primary visual cortex are developed and released
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One uses compartmental-neuron models and the other point-neuron models
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The models recapitulate observations from in vivo experimental data
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Simulations identify experimentally testable predictions about cortex circuitry" |