Find models by
Find models for
Find models of
Electrical synapses (gap junctions)
SenseLab mailing list
ModelDB related resources
Computational neuroscience ecosystem
Models in a git repository
Tonic-clonic transitions in a seizure simulation (Lytton and Omurtag 2007)
Download zip file
Help downloading and running models
Versions on GitHub
"... The authors have ... computationally manageable networks of moderate size consisting of 1,000 to 3,000 neurons with multiple intrinsic and synaptic properties. Experiments on these simulations demonstrated the presence of epileptiform behavior in the form of repetitive high-intensity population events (clonic behavior) or latch-up with near maximal activity (tonic behavior). ... Several simulations revealed the importance of random coincident inputs to shift a network from a low-activation to a high-activation epileptiform state. Finally, a simulated anticonvulsant acting on excitability tended to preferentially decrease tonic activity."
Lytton WW, Omurtag A (2007) Tonic-clonic transitions in computer simulation.
J Clin Neurophysiol
(Click on a link to find other models with that property)
Lytton, William [billl at neurosim.downstate.edu];
Download the displayed file
Other models using nstim.mod:
Computational Surgery (Lytton et al. 2011)
Cortical model with reinforcement learning drives realistic virtual arm (Dura-Bernal et al 2015)
Electrostimulation to reduce synaptic scaling driven progression of Alzheimers (Rowan et al. 2014)
Emergence of physiological oscillation frequencies in neocortex simulations (Neymotin et al. 2011)
JitCon: Just in time connectivity for large spiking networks (Lytton et al. 2008)
Motor cortex microcircuit simulation based on brain activity mapping (Chadderdon et al. 2014)
Prosthetic electrostimulation for information flow repair in a neocortical simulation (Kerr 2012)
Reinforcement learning of targeted movement (Chadderdon et al. 2012)
Sensorimotor cortex reinforcement learning of 2-joint virtual arm reaching (Neymotin et al. 2013)
Synaptic scaling balances learning in a spiking model of neocortex (Rowan & Neymotin 2013)
The virtual slice setup (Lytton et al. 2008)
ModelDB scripts have detected that binary file '/b07dec17/CONNTABLES02.cpnqs' is not displayable. You may download the file to examine if desired.
<- Select file from this column.
Loading data, please wait...
Questions, comments, problems? Email the
How to cite ModelDB
© This site is Copyright 2018 Shepherd Lab, Yale University