Calcium spikes in basal dendrites (Kampa and Stuart 2006)

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Accession:108458
This model was published in Kampa & Stuart (2006) J Neurosci 26(28):7424-32. The simulation creates two plots showing voltage and calcium changes in basal dendrites of layer 5 pyramidal neurons during action potential backpropagation. created by B. Kampa (2006)
Reference:
1 . Kampa BM, Stuart GJ (2006) Calcium spikes in basal dendrites of layer 5 pyramidal neurons during action potential bursts. J Neurosci 26:7424-32 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Neuron or other electrically excitable cell;
Brain Region(s)/Organism:
Cell Type(s): Neocortex U1 L5B pyramidal pyramidal tract GLU cell;
Channel(s): I L high threshold; I T low threshold; I A; I Sodium; I Potassium;
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment: NEURON;
Model Concept(s): Dendritic Action Potentials; Active Dendrites; Action Potentials; Synaptic Integration; Calcium dynamics;
Implementer(s): Kampa, Bjorn M [Bjoern.Kampa at anu.edu.au];
Search NeuronDB for information about:  Neocortex U1 L5B pyramidal pyramidal tract GLU cell; I L high threshold; I T low threshold; I A; I Sodium; I Potassium;
{load_file("nrngui.hoc")}
objectvar save_window_, rvp_
objectvar scene_vector_[4]
objectvar ocbox_, ocbox_list_, scene_, scene_list_
{ocbox_list_ = new List()  scene_list_ = new List()}
{pwman_place(0,0,0)}
{
xpanel("RunControl", 0)
v_init = -65
xvalue("Init","v_init", 1,"stdinit()", 1, 1 )
xbutton("Init & Run","run()")
xbutton("Stop","stoprun=1")
runStopAt = 5
xvalue("Continue til","runStopAt", 1,"{continuerun(runStopAt) stoprun=1}", 1, 1 )
runStopIn = 1
xvalue("Continue for","runStopIn", 1,"{continuerun(t + runStopIn) stoprun=1}", 1, 1 )
xbutton("Single Step","steprun()")
t = 1100
xvalue("t","t", 2 )
tstop = 1100
xvalue("Tstop","tstop", 1,"tstop_changed()", 0, 1 )
dt = 0.1
xvalue("dt","dt", 1,"setdt()", 0, 1 )
steps_per_ms = 10
xvalue("Points plotted/ms","steps_per_ms", 1,"setdt()", 0, 1 )
xcheckbox("Quiet",&stdrun_quiet,"")
realtime = 21
xvalue("Real Time","realtime", 0,"", 0, 1 )
xpanel(858,447)
}
{
save_window_ = new Graph(0)
save_window_.size(1000,1100,-80,50)
scene_vector_[2] = save_window_
{save_window_.view(1000, -80, 50, 130, 0, 277, 621, 396.1)}
graphList[0].append(save_window_)
save_window_.save_name("graphList[0].")
save_window_.addexpr("v(.5)", 1, 1, 0.8, 0.9, 2)
save_window_.addvar("dend1[1010].v(0.75)", 2, 1, 0.8, 0.9, 2)
save_window_.addvar("dend1[1016].v(1)", 3, 1, 0.8, 0.9, 2)
save_window_.addvar("dend1[1045].v(0.5)", 4, 1, 0.8, 0.9, 2)
}
{
save_window_ = new Graph(0)
save_window_.size(999,1100,0.02,0.46)
scene_vector_[3] = save_window_
{save_window_.view(999, 0.02, 101, 0.44, 769, 12, 300.6, 200.8)}
graphList[1].append(save_window_)
save_window_.save_name("graphList[1].")
save_window_.addexpr("dend1[1010].cai(0.5)", 2, 1, 0.662275, 0.980677, 2)
save_window_.addexpr("dend1[1016].cai(0.5)", 3, 1, 0.662275, 0.962749, 2)
save_window_.addexpr("dend1[1045].cai(0.5)", 4, 1, 0.656287, 0.940339, 2)
}
objectvar scene_vector_[1]
{doNotify()}

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