ModelDB: Cerebellar Golgi cell (Solinas et al. 2007a, 2007b)

Cerebellar Golgi cell (Solinas et al. 2007a, 2007b)

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Accession:112685

"... Our results suggest that a complex complement of ionic mechanisms is needed to fine-tune separate aspects of the neuronal response dynamics. Simulations also suggest that the Golgi cell may exploit these mechanisms to obtain a fine regulation of timing of incoming mossy fiber responses and granular layer circuit oscillation and bursting."
References:
1 . Solinas S, Forti L, Cesana E, Mapelli J, De Schutter E, D'Angelo E (2007) Computational reconstruction of pacemaking and intrinsic electroresponsiveness in cerebellar Golgi cells. Front Cell Neurosci 1:2 [PubMed]
2 . Solinas S, Forti L, Cesana E, Mapelli J, De Schutter E, D'Angelo E (2007) Fast-reset of pacemaking and theta-frequency resonance patterns in cerebellar golgi cells: simulations of their impact in vivo. Front Cell Neurosci 1:4 [PubMed]

Model Information (Click on a link to find other models with that property)

Model Type:	Neuron or other electrically excitable cell;
Brain Region(s)/Organism:	Cerebellum;
Cell Type(s):	Cerebellum golgi cell;
Channel(s):	I Na,p; I Na,t; I T low threshold; I A; I K; I M; I K,Ca; I Sodium; I Calcium; I Potassium; I h;
Gap Junctions:
Receptor(s):
Gene(s):	HCN1;
Transmitter(s):
Simulation Environment:	NEURON; neuroConstruct (web link to model);
Model Concept(s):	Activity Patterns; Oscillations;
Implementer(s):	D'Angelo, Egidio [dangelo at unipv.it]; De Schutter, Erik [erik at oist.jp];