Cerebellar Golgi cell (Solinas et al. 2007a, 2007b)

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Accession:112685
"... Our results suggest that a complex complement of ionic mechanisms is needed to fine-tune separate aspects of the neuronal response dynamics. Simulations also suggest that the Golgi cell may exploit these mechanisms to obtain a fine regulation of timing of incoming mossy fiber responses and granular layer circuit oscillation and bursting."
Reference:
1 . Solinas S, Forti L, Cesana E, Mapelli J, De Schutter E, D`Angelo E (2007) Computational reconstruction of pacemaking and intrinsic electroresponsiveness in cerebellar golgi cells. Front. Cell. Neurosci. 1:2:1-12 [PubMed]
2 . Solinas S, Forti L, Cesana E, Mapelli J, De Schutter E, D`Angelo E (2007) Fast-reset of pacemaking and theta-frequency resonance patterns in cerebellar golgi cells: Simulations of their impact in vivo. Front. Cell. Neurosci. 1:4:1-9 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Neuron or other electrically excitable cell;
Brain Region(s)/Organism: Cerebellum;
Cell Type(s): Cerebellum golgi cell;
Channel(s): I Na,p; I Na,t; I T low threshold; I A; I K; I M; I K,Ca; I Sodium; I Calcium; I Potassium;
Gap Junctions:
Receptor(s):
Gene(s):
Transmitter(s):
Simulation Environment: NEURON; neuroConstruct (web link to model);
Model Concept(s): Activity Patterns; Oscillations;
Implementer(s): D'Angelo, Egidio [dangelo at unipv.it]; De Schutter, Erik [erik at oist.jp];
Search NeuronDB for information about:  I Na,p; I Na,t; I T low threshold; I A; I K; I M; I K,Ca; I Sodium; I Calcium; I Potassium;

Solinas S, Forti L, Cesana E, Mapelli J, De Schutter E, D`Angelo E (2007) Computational reconstruction of pacemaking and intrinsic electroresponsiveness in cerebellar golgi cells. Front. Cell. Neurosci. 1:2:1-12[PubMed]

References and models cited by this paper

References and models that cite this paper

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   Cerebellar purkinje cell (De Schutter and Bower 1994) [Model]

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   Network model of the granular layer of the cerebellar cortex (Maex, De Schutter 1998) [Model]

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Solinas S, Forti L, Cesana E, Mapelli J, De Schutter E, D`Angelo E (2007) Fast-reset of pacemaking and theta-frequency resonance patterns in cerebellar golgi cells: Simulations of their impact in vivo. Front. Cell. Neurosci. 1:4:1-9 [Journal] [PubMed]

   Cerebellar Golgi cell (Solinas et al. 2007a, 2007b) [Model]

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   Controlling KCa channels with different Ca2+ buffering models in Purkinje cell (Anwar et al. 2012) [Model]

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   [1 reconstructed morphology on NeuroMorpho.Org]
   Calcium dynamics depend on dendritic diameters (Anwar et al. 2014) [Model]

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   Reconstructing cerebellar granule layer evoked LFP using convolution (ReConv) (Diwakar et al. 2011) [Model]

Diwakar S, Magistretti J, Goldfarb M, Naldi G, D`Angelo E (2009) Axonal Na+ channels ensure fast spike activation and back-propagation in cerebellar granule cells J Neurophysiol 101(2):519-32 [Journal] [PubMed]

   Multicompartmental cerebellar granule cell model (Diwakar et al. 2009) [Model]

Garrido JA, Ros E, D`Angelo E (2013) Spike timing regulation on the millisecond scale by distributed synaptic plasticity at the cerebellum input stage: a simulation study Front. Comput. Neurosci. 7:64 [Journal] [PubMed]

   Distributed synaptic plasticity and spike timing (Garrido et al. 2013) [Model]

Gleeson P, Crook S, Cannon RC, Hines ML, Billings GO, Farinella M, Morse TM, Davison AP, Ray (2010) NeuroML: a language for describing data driven models of neurons and networks with a high degree of biological detail. PLoS Comput Biol 6:e1000815 [Journal] [PubMed]

Parasuram H, Nair B, D`Angelo E, Hines M, Naldi G, Diwakar S Computational modeling of single neuron extracellular electric potentials and network Local Field Potentials using LFPsim Front. Comput. Neurosci. 10:65 [Journal]

   Modeling single neuron LFPs and extracellular potentials with LFPsim (Parasuram et al. 2016) [Model]

Simões de Souza F, De Schutter E (2011) Robustness effect of gap junctions between Golgi cells on cerebellar cortex oscillations Neural Systems & Circuits 1:7:1-19 [Journal]

   Cerebellar cortex oscil. robustness from Golgi cell gap jncs (Simoes de Souza and De Schutter 2011) [Model]

Solinas S, Forti L, Cesana E, Mapelli J, De Schutter E, D`Angelo E (2007) Fast-reset of pacemaking and theta-frequency resonance patterns in cerebellar golgi cells: Simulations of their impact in vivo. Front. Cell. Neurosci. 1:4:1-9 [Journal] [PubMed]

   Cerebellar Golgi cell (Solinas et al. 2007a, 2007b) [Model]

Torben-Nielsen B, Segev I, Yarom Y (2012) The generation of phase differences and frequency changes in a network model of inferior olive subthreshold oscillations. PLoS Comput Biol 8:e1002580 [Journal] [PubMed]

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Vervaeke K, Lorincz A, Gleeson P, Farinella M, Nusser Z, Silver RA (2010) Rapid Desynchronization of an Electrically Coupled Interneuron Network with Sparse Excitatory Synaptic Input. Neuron 67:435-451 [Journal] [PubMed]

   [2 reconstructed morphologies on NeuroMorpho.Org]
   Rapid desynchronization of an electrically coupled Golgi cell network (Vervaeke et al. 2010) [Model]

(73 refs)

Solinas S, Forti L, Cesana E, Mapelli J, De Schutter E, D`Angelo E (2007) Fast-reset of pacemaking and theta-frequency resonance patterns in cerebellar golgi cells: Simulations of their impact in vivo. Front. Cell. Neurosci. 1:4:1-9[PubMed]

References and models cited by this paper

References and models that cite this paper

Buzsaki G (2006) Rhythms of the Brain

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   Cerebellar Golgi cell (Solinas et al. 2007a, 2007b) [Model]

Stocker M (2004) Ca(2+)-activated K+ channels: molecular determinants and function of the SK family. Nat Rev Neurosci 5:758-70 [PubMed]

Tahon K, Volny-Luraghi A, De Schutter E (2005) Temporal characteristics of tactile stimuli influence the response profile of cerebellar Golgi cells. Neurosci Lett 390:156-61 [PubMed]

Volny-Luraghi A, Maex R, Vosdagger B, De Schutter E (2002) Peripheral stimuli excite coronal beams of Golgi cells in rat cerebellar cortex. Neuroscience 113:363-73 [PubMed]

Vos BP, Maex R, Volny-Luraghi A, De Schutter E (1999) Parallel fibers synchronize spontaneous activity in cerebellar Golgi cells. J Neurosci 19:RC6 [PubMed]

Vos BP, Volny-Luraghi A, De Schutter E (1999) Cerebellar Golgi cells in the rat: receptive fields and timing of responses to facial stimulation. Eur J Neurosci 11:2621-34 [PubMed]

Vos BP, Volny-Luraghi A, Maex R, De Schutter E (2000) Precise spike timing of tactile-evoked cerebellar Golgi cell responses: a reflection of combined mossy fiber and parallel fiber activation? Prog Brain Res 124:95-106 [PubMed]

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Yamada WM, Koch C, Adams PR (1998) Multiple channels and calcium dynamics. Methods In Neuronal Modeling: From Synapses To Networks, Koch C:Segev I, ed. pp.137

Diwakar S, Magistretti J, Goldfarb M, Naldi G, D`Angelo E (2009) Axonal Na+ channels ensure fast spike activation and back-propagation in cerebellar granule cells J Neurophysiol 101(2):519-32 [Journal] [PubMed]

   Multicompartmental cerebellar granule cell model (Diwakar et al. 2009) [Model]

Solinas S, Forti L, Cesana E, Mapelli J, De Schutter E, D`Angelo E (2007) Computational reconstruction of pacemaking and intrinsic electroresponsiveness in cerebellar golgi cells. Front. Cell. Neurosci. 1:2:1-12 [Journal] [PubMed]

   Cerebellar Golgi cell (Solinas et al. 2007a, 2007b) [Model]

(49 refs)