MEG of Somatosensory Neocortex (Jones et al. 2007)

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Accession:113732
"... To make a direct and principled connection between the SI (somatosensory primary neocortex magnetoencephalography) waveform and underlying neural dynamics, we developed a biophysically realistic computational SI model that contained excitatory and inhibitory neurons in supragranular and infragranular layers. ... our model provides a biophysically realistic solution to the MEG signal and can predict the electrophysiological correlates of human perception."
Reference:
1 . Jones SR, Pritchett DL, Stufflebeam SM, Hämäläinen M, Moore CI (2007) Neural correlates of tactile detection: a combined magnetoencephalography and biophysically based computational modeling study. J Neurosci 27:10751-64 [PubMed]
Model Information (Click on a link to find other models with that property)
Model Type: Realistic Network;
Brain Region(s)/Organism:
Cell Type(s): Neocortex L5/6 pyramidal GLU cell; Neocortex U1 L2/6 pyramidal intratelencephalic GLU cell;
Channel(s): I T low threshold; I K; I M; I K,Ca; I Sodium; I Calcium; I R;
Gap Junctions:
Receptor(s): GabaA; GabaB; AMPA; NMDA;
Gene(s):
Transmitter(s): Gaba; Glutamate;
Simulation Environment: NEURON;
Model Concept(s): Magnetoencephalography; Touch;
Implementer(s): Sikora, Michael [Sikora at umn.edu];
Search NeuronDB for information about:  Neocortex L5/6 pyramidal GLU cell; Neocortex U1 L2/6 pyramidal intratelencephalic GLU cell; GabaA; GabaB; AMPA; NMDA; I T low threshold; I K; I M; I K,Ca; I Sodium; I Calcium; I R; Gaba; Glutamate;
// Intitialization file for somatosensory cortex simulation

/*
These cells are defined above in sj-cortex.hoc:

PL5[10]   10 Layer V Pyramidal Cells
Apical compartments 0-4
Basal               5-7
Soma                 8
IPL5[3]   3 Layer V inhibitory
PL2[10]   10 Layer II/III  Pyramidal Cells
Apical compartments 0-3
Basal               4-6
Soma                 7
IPL2[3]   3 Layer II/III inhibitory
FF        Feed-forward
FB        Feed-back
FF2       Feed-forward
*/

load_file("nrngui.hoc")
load_file("sj3-cortex.hoc")
load_file("wiring_proc.hoc")
load_file("noise.hoc")
//
UnoiseV(-0.3,0.3)
UnoiseII(-0.3,0.3)
UnoiseIPL5(-0.3,0.3)
UnoiseIPL2(-0.3,0.3)
/*
xpanel("disconnect")
xbutton("disconnect all","unconnect()")
xpanel()
*/

print "Load wiring configuration file. Eg. wiring-config_suprathreshold.hoc "

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